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The Effects Of Social And Nonsocial Contextual Stimuli On The Renewal Of Cocaine Seeking, Bree Humburg
The Effects Of Social And Nonsocial Contextual Stimuli On The Renewal Of Cocaine Seeking, Bree Humburg
Theses and Dissertations--Psychology
Those with substance use disorders can undergo craving and relapse when re-exposed to a drug-associated context. This study determined if renewal of cocaine seeking is differentially controlled by contexts consisting of social and/or nonsocial stimuli. Experiment 1, rats self-administered cocaine in Context A which included a social peer and house light illumination. Following self-administration, rats were randomly assigned to an AAA or ABA group for extinction and renewal. For the AAA rats, context was similar to self-administration; for ABA rats, the drug-associated stimuli (peer and house light) were removed (Context B). Following extinction, renewal of cocaine seeking was examined by …