Open Access. Powered by Scholars. Published by Universities.®

Psychology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 31 - 60 of 100

Full-Text Articles in Psychology

Humor Improves Women’S But Impairs Men’S Iowa Gambling Task Performance, Jorge Flores‑Torres, Lydia Gómez‑Pérez, Kateri Mcrae, Vladimir López, Ivan Rubio, Eugenio Rodriguez Nov 2019

Humor Improves Women’S But Impairs Men’S Iowa Gambling Task Performance, Jorge Flores‑Torres, Lydia Gómez‑Pérez, Kateri Mcrae, Vladimir López, Ivan Rubio, Eugenio Rodriguez

Psychology: Faculty Scholarship

The Iowa Gambling Task (IGT) is a popular method for examining real-life decision-making. Research has shown gender related differences in performance, in that men consistently outperform women. It has been suggested that these performance differences are related to decreased emotional control in women compared to men. Given the likely role of emotion in these gender differences, in the present study, we examine the effect of a humor induction on IGT performance and whether the effect of humor is moderated by gender. IGT performance and parameters from the Expectancy Valence Model (EVM) were measured in 68 university students (34 men; mean …


Neural Processing Of Infant And Adult Face Emotion And Maternal Exposure To Childhood Maltreatment, Aviva K. Olsavsky, Joel Stoddard, Andrew Erhart, Rebekah C. Tribble, Pilyoung Kim Sep 2019

Neural Processing Of Infant And Adult Face Emotion And Maternal Exposure To Childhood Maltreatment, Aviva K. Olsavsky, Joel Stoddard, Andrew Erhart, Rebekah C. Tribble, Pilyoung Kim

Psychology: Faculty Scholarship

Face processing in mothers is linked to mother–infant social communication, which is critical for parenting and in turn for child development. Neuroimaging studies of child maltreatment-exposed (CME) mothers are sparse compared to studies of mothers with postpartum depression, which have suggested blunted amygdala reactivity to infant stimuli. We expected to see a similar pattern in CME mothers. Based on broader studies in trauma-exposed populations, we anticipated increased amygdala reactivity to negative adult face stimuli in a comparison task in CME mothers given heightened evaluation of potential threat. We examined Neuroimaging studies of mothers with childhood maltreatment exposure (CME) (18–37 years …


Across Continents And Demographics, Unpredictable Maternal Signals Are Associated With Children's Cognitive Function, Elysia Poggi Davis, Riikka Korja, Linnea Karlsson, Laura M. Glynn, Curt A. Sandman, Brian Vegetabile, Eeva-Leena Kataja, Saara Nolvi, Eija Sinervä, Juho Pelto, Hasse Karlsson, Hal S. Stern, Tallie Z. Baram Aug 2019

Across Continents And Demographics, Unpredictable Maternal Signals Are Associated With Children's Cognitive Function, Elysia Poggi Davis, Riikka Korja, Linnea Karlsson, Laura M. Glynn, Curt A. Sandman, Brian Vegetabile, Eeva-Leena Kataja, Saara Nolvi, Eija Sinervä, Juho Pelto, Hasse Karlsson, Hal S. Stern, Tallie Z. Baram

Psychology: Faculty Scholarship

Background

Early life experiences have persisting influence on brain function throughout life. Maternal signals constitute a primary source of early life experiences, and their quantity and quality during sensitive developmental periods exert enduring effects on cognitive function and emotional and social behaviors. Here we examined if, in addition to established qualitative dimensions of maternal behavior during her interactions with her infant and child, patterns of maternal signals may contribute to the maturation of children's executive functions. We focused primarily on effortful control, a potent predictor of mental health outcomes later in life.

Methods

In two independent prospective cohorts in Turku, …


Multivariate Genome-Wide Association Study Of Rapid Automatised Naming And Rapid Alternating Stimulus In Hispanic American And African–American Youth, Dongnhu Thuy Truong, Andrew Kenneth Adams, Steven Paniagua, Jan C. Frijters, Richard Boada, Dina E. Hill, Maureen W. Lovett, E Mark Mahone, Erik G. Willcutt, Maryanne Wolf, John C. Defries, Alessandro Gialluisi, Clyde Francks, Simon E. Fisher, Richard K. Olson, Bruce F. Pennington, Shelley D. Smith, Joan Bosson-Heenan, Jeffrey R. Gruen Aug 2019

Multivariate Genome-Wide Association Study Of Rapid Automatised Naming And Rapid Alternating Stimulus In Hispanic American And African–American Youth, Dongnhu Thuy Truong, Andrew Kenneth Adams, Steven Paniagua, Jan C. Frijters, Richard Boada, Dina E. Hill, Maureen W. Lovett, E Mark Mahone, Erik G. Willcutt, Maryanne Wolf, John C. Defries, Alessandro Gialluisi, Clyde Francks, Simon E. Fisher, Richard K. Olson, Bruce F. Pennington, Shelley D. Smith, Joan Bosson-Heenan, Jeffrey R. Gruen

Psychology: Faculty Scholarship

Background: Rapid automatised naming (RAN) and rapid alternating stimulus (RAS) are reliable predictors of reading disability. The underlying biology of reading disability is poorly understood. However, the high correlation among RAN, RAS and reading could be attributable to shared genetic factors that contribute to common biological mechanisms.

Objective: To identify shared genetic factors that contribute to RAN and RAS performance using a multivariate approach.

Methods: We conducted a multivariate genome-wide association analysis of RAN Objects, RAN Letters and RAS Letters/Numbers in a sample of 1331 Hispanic American and African-American youth. Follow-up neuroimaging genetic analysis of cortical regions associated with reading …


“A” For Effort: Rewarding Effortful Retrieval Attempts Improves Learning From General Knowledge Errors In Women, Damon Abraham, Kateri Mcrae, Jennifer A. Mangels Jun 2019

“A” For Effort: Rewarding Effortful Retrieval Attempts Improves Learning From General Knowledge Errors In Women, Damon Abraham, Kateri Mcrae, Jennifer A. Mangels

Psychology: Faculty Scholarship

Previous research has shown that the prospect of attaining a reward can promote task-engagement, up-regulate attention toward reward-relevant information, and facilitate enhanced encoding of new information into declarative memory. However, past research on reward-based enhancement of declarative memory has focused primarily on paradigms in which rewards are contingent upon accurate responses. Yet, findings from test-enhanced learning show that making errors can also be useful for learning if those errors represent effortful retrieval attempts and are followed by corrective feedback. Here, we used a challenging general knowledge task to examine the effects of explicitly rewarding retrieval effort, defined as a semantically …


Genome-Wide Association Scan Identifies New Variants Associated With A Cognitive Predictor Of Dyslexia, Alessandro Gialluisi, Till F. M. Andlauer, Nazanin Mirza-Schreiber, Kristina Moll, Jessica Becker, Per Hoffmann, Kerstin U. Ludwig, Darina Czamara, Beate St Pourcain, William Brandler, Ferenc Honbolygó, Dénes Tóth, Valéria Csépe, Guillaume Huguet, Andrew P. Morris, Jacqueline Hulslander, Erik G. Willcutt, John C. Defries, Richard K. Olson, Shelley D. Smith, Bruce F. Pennington, Anniek Vaessen, Urs Maurer, Heikki Lyytinen, Myriam Peyrard-Janvid, Paavo H. T. Leppänen, Daniel Brandeis, Milene Bonte, John F. Stein, Joel B. Talcott, Fabien Fauchereau, Arndt Wilcke, Clyde Francks, Thomas Bourgeron, Anthony P. Monaco, Franck Ramus, Karin Landerl, Juha Kere, Thomas S. Scerri, Silvia Paracchini, Simon E. Fisher, Johannes Schumacher, Markus M. Nöthen, Bertram Müller-Myhsok, Gerd Schulte-Körne Feb 2019

Genome-Wide Association Scan Identifies New Variants Associated With A Cognitive Predictor Of Dyslexia, Alessandro Gialluisi, Till F. M. Andlauer, Nazanin Mirza-Schreiber, Kristina Moll, Jessica Becker, Per Hoffmann, Kerstin U. Ludwig, Darina Czamara, Beate St Pourcain, William Brandler, Ferenc Honbolygó, Dénes Tóth, Valéria Csépe, Guillaume Huguet, Andrew P. Morris, Jacqueline Hulslander, Erik G. Willcutt, John C. Defries, Richard K. Olson, Shelley D. Smith, Bruce F. Pennington, Anniek Vaessen, Urs Maurer, Heikki Lyytinen, Myriam Peyrard-Janvid, Paavo H. T. Leppänen, Daniel Brandeis, Milene Bonte, John F. Stein, Joel B. Talcott, Fabien Fauchereau, Arndt Wilcke, Clyde Francks, Thomas Bourgeron, Anthony P. Monaco, Franck Ramus, Karin Landerl, Juha Kere, Thomas S. Scerri, Silvia Paracchini, Simon E. Fisher, Johannes Schumacher, Markus M. Nöthen, Bertram Müller-Myhsok, Gerd Schulte-Körne

Psychology: Faculty Scholarship

Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on school and psychosocial development and high comorbidity with conditions like attention-deficit hyperactivity disorder (ADHD), depression, and anxiety. DD is characterized by deficits in different cognitive skills, including word reading, spelling, rapid naming, and phonology. To investigate the genetic basis of DD, we conducted a genome-wide association study (GWAS) of these skills within one of the largest studies available, including nine cohorts of reading-impaired and typically developing children of European ancestry (N = 2562–3468). We observed a genome-wide significant effect (p < 1 × 10−8) on rapid automatized naming of letters (RANlet) for variants on 18q12.2, within MIR924HG (micro-RNA …


B.F. Skinner's Theory Of Performance Excellence: A Radical Behavioral Perspective, Thomas Fritze Jan 2019

B.F. Skinner's Theory Of Performance Excellence: A Radical Behavioral Perspective, Thomas Fritze

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Burrhus Frederic (B.F.) Skinner was a revolutionary in the field of psychology, particularly noted for his development of a philosophy of science and an approach to psychological study labeled radical behaviorism (Rachlin, 1995). To Skinner, psychology was synonymous with an organism's interactions between its environment and its own behavior - and behavior was defined accordingly. This way of studying psychology differed greatly from preceding behavioral iterations in psychology and kept up with advances in ·established fields of science. Due to the deficiencies of the behavioral tradition coming before Skinner, misunderstandings by many psychologists and scientists of the Skinnerian approach were …


Integration And Segmentation Conflict During Ensemble Coding Of Aspect Ratio, Elric Matthew Elias Jan 2019

Integration And Segmentation Conflict During Ensemble Coding Of Aspect Ratio, Elric Matthew Elias

Electronic Theses and Dissertations

The visual system often integrates information that "goes together". Once information has been integrated, summary information (e.g., average emotion or average size) can be extracted; this occurs during ensemble coding. Integration thus allows for fast and efficient generalizations about sets to be made. In contrast, the visual system sometimes segments input that does not go together. For example, the perception of objects can be exaggerated away from natural category boundaries (e.g., a perfect circle is a category boundary; it is neither "flat" nor "tall"). Segmentation allows the visual system to make quick categorical distinctions. Much of the time, integration …


Defining The Relationship: Intentional Decision-Making And Sexual Risk In Adolescent And Young Adult Romantic Relationships, Kayla Knopp Jan 2019

Defining The Relationship: Intentional Decision-Making And Sexual Risk In Adolescent And Young Adult Romantic Relationships, Kayla Knopp

Electronic Theses and Dissertations

This dissertation presents three manuscripts addressing different sets of findings related to the "defining the relationship" (DTR) talk in adolescents' and young adults' romantic relationships. Paper 1 describes descriptive results from two studies, one utilizing a college undergraduate young adult sample (N = 341) and the other using a nationwide online sample of 15 to 17-year-old adolescents (N = 248). Key findings from Paper 1 indicate that DTR talks were used frequently in the relationships of young people, and were associated with relationship commitment and sexual behaviors. Paper 2 describes more in-depth analyses testing associations between having a …


A Dyadic Perspective On Young Adult Dating Aggression, Ann Lantagne Jan 2019

A Dyadic Perspective On Young Adult Dating Aggression, Ann Lantagne

Electronic Theses and Dissertations

Guided by the dynamic developmental systems theory (Capaldi, Knoble, Shortt, & Kim, 2012), the present studies examined individual and relationship level risk factors for dating aggression. A series of Actor Partner Interdependence Models (APIM; Kenny, 1996; Kenny & Cook, 1999) were used to assess associations between males' and females' risk factors and dating aggression within 137 young adult couples. Findings indicated that both partners' reports of a number of relationship characteristics were associated with aggression, including negative interactions, satisfaction, jealousy, and anxious and avoidant relational styles. Moreover, there were actor partner interactions between male and female jealousy, anxious styles, and …


Beyond School Engagement: School Adaptation And Its Role In Bolstering Resilience Among Youth Who Have Been Involved With Child Welfare Services, Skyler S. Leonard Jan 2019

Beyond School Engagement: School Adaptation And Its Role In Bolstering Resilience Among Youth Who Have Been Involved With Child Welfare Services, Skyler S. Leonard

Electronic Theses and Dissertations

Objective: Youth involved with the child welfare system are at significant risk of poor school functioning and mental health. Little research has explored how the connection to school impacts known relationships between adversity and youth outcomes. The following project sought to shed light on the role of schools in conferring risk or resilience for youth in contact with the child welfare system, with regard to their mental health. The overall aims of this project were to (1) improve our conceptualization of school adaptation, with particular attention to individual variation along multiple dimensions of school adaptation, (2) examine the relationship of …


Anti-Fat Bias And Attentional Capture, Larissa Catherine Miller Jan 2019

Anti-Fat Bias And Attentional Capture, Larissa Catherine Miller

Electronic Theses and Dissertations

Explicitly-rated anti-fat attitudes are correlated with weight-based discrimination, which is rampant in society today as many countries grapple with soaring rates of obesity. Early perceptual processes, such as conscious awareness and visual attention, may be biased based on the weight of the perceived or the perceiver, or any number of individual perceiver characteristics regarding weight-biased attitudes and experiences. The three experiments presented used continuous-flash suppression (CFS) to mask body stimuli, thereby hoping to gain insight into attentional capture of unseen images and its relation to anti-fat attitudes. The pattern of findings in the three experiments presented suggest that what makes …


Commitment And Romantic Alternative Monitoring, Lane Laurel Ritchie Jan 2019

Commitment And Romantic Alternative Monitoring, Lane Laurel Ritchie

Electronic Theses and Dissertations

This dissertation examines cognitive and behavioral factors involved in the management of potential alternative partners. Two studies are described here, each in a separate paper. The first study investigates perceptions of potential alternative partners as presented in an experimental paradigm (Study 1) and the second study examines links between alternative monitoring and relationship outcomes, measured longitudinally in survey research (Study 2). In the first study, Perceptual Downgrading and Relationship Commitment, I use a well-established paradigm to test a novel series of questions: Do individuals in committed relationships perceive attractive others as less attractive than single people do? This phenomenon …


Individual Adjustment As A Predictor Of Improvements In Romantic Relationship Quality From Adolescence To Adulthood, Jamie Novak Shoop Jan 2019

Individual Adjustment As A Predictor Of Improvements In Romantic Relationship Quality From Adolescence To Adulthood, Jamie Novak Shoop

Electronic Theses and Dissertations

Previous work suggests that individuals who experience a poor quality romantic relationship during adolescence are at heightened risk of experiencing poor quality romantic relationships in adulthood. However, this literature has not yet identified factors that may predict which individuals will go on to experience improved romantic relationship quality in adulthood, despite having experienced a poor quality romantic relationship during adolescence. The goal of the current study was to examine whether adolescents' psychosocial adjustment (internalizing and externalizing symptoms, substance use, and self-esteem) predicted improvements in the quality of their subsequent romantic relationships. Data were drawn from a community sample of 200 …


The Cultural Transmission Of Gender Roles In Childhood, Sarah Ariel Lamer Jan 2019

The Cultural Transmission Of Gender Roles In Childhood, Sarah Ariel Lamer

Electronic Theses and Dissertations

In the present work, I summarize extant theories and evidence on how children learn about gender roles and test an ecological framework for gender-role learning (i.e., the Gendered Ecology Model). Existing theory has demonstrated that children begin to form symbolic representations of gender as young as 9 months and acquire basic gender stereotypes about behaviors and activities considered appropriate for each gender by 3 years. Theories have proposed several potential sources and moderators of how children learn about the roles that women and men generally hold. However, no theories have examined these sources from an ecological approach, leaving open the …


Social Support Satisfaction As A Protective Factor For Postpartum Maternal Distress, Amy-Lynn Elisabeth Anderson Jan 2019

Social Support Satisfaction As A Protective Factor For Postpartum Maternal Distress, Amy-Lynn Elisabeth Anderson

Electronic Theses and Dissertations

Social support has been identified as a protective factor for postpartum maternal distress, a prevalent women's health issue, and most research focuses on the amount of support women receive. However, research in this area has failed to explore whether increasing satisfaction with social support may be a worthwhile approach to alleviating postpartum maternal distress, beyond increasing amounts. There is also little known regarding specific aspects of support, like satisfaction with emotional and instrumental support, that might lead to differences in postpartum distress outcomes. In this prospective, longitudinal study, we hypothesized that greater social support satisfaction will be associated with less …


Brief Report: Attentional Cueing To Images Of Social Interactions Is Automatic For Neurotypical Individuals But Not Those With Asc, Marcus Neil Morrisey, Catherine L. Reed, Daniel N. Mcintosh, M. D. Rutherford Sep 2018

Brief Report: Attentional Cueing To Images Of Social Interactions Is Automatic For Neurotypical Individuals But Not Those With Asc, Marcus Neil Morrisey, Catherine L. Reed, Daniel N. Mcintosh, M. D. Rutherford

Psychology: Faculty Scholarship

Human actions induce attentional orienting toward the target of the action. We examined the influence of action cueing in social (man throwing toward a human) and non-social (man throwing toward a tree) contexts in observers with and without autism spectrum condition (ASC). Results suggested that a social interaction enhanced the cueing effect for neurotypical participants. Participants with ASC did not benefit from non-predictive cues and were slower in social contexts, although they benefitted from reliably predictive cues. Social orienting appears to be automatic in the context of an implied social interaction for neurotypical observers, but not those with ASC. Neurotypical …


Role Of Executive Function And Alcohol-Sex Schema In The Relationship Between Alcohol Use And Sexual Assault, Michelle Seulki Lee Aug 2018

Role Of Executive Function And Alcohol-Sex Schema In The Relationship Between Alcohol Use And Sexual Assault, Michelle Seulki Lee

Electronic Theses and Dissertations

Heavy alcohol use and sexual assault are significant problems among women attending college. The current study examined the relationship between sexual assault and alcohol use across a four-month period and the role of executive function (EF) and alcohol-sex schema in this relationship. Participants were 176 women undergraduate students with a mean age of 19.50 years (SD = 1.30), with 85 participating in a second survey four months later. Participants completed self-report questionnaires regarding alcohol use and sexual assault, a battery of EF tasks, and a lexical decision task assessing alcohol-sex schema. Sexual assault significantly predicted alcohol use four months …


Predicting And Shifting Attitudes Toward Immigrants And Immigration: Testing A Model And Communication Strategy, Tejaswinhi Srinivas Aug 2018

Predicting And Shifting Attitudes Toward Immigrants And Immigration: Testing A Model And Communication Strategy, Tejaswinhi Srinivas

Electronic Theses and Dissertations

Research in intergroup relations has found evidence for economic and moral explanations for negative attitudes toward immigrants and immigration (NATII), and has evaluated various communication strategies for shifting these attitudes. However, no research to date has provided a cultural explanation for NATII, or tested and compared the impact of communication strategies for reducing NATII, in the American context. This study extended prior research in three ways. First, we tested a model that linked various psychosocial factors together (i.e., right-wing authoritarianism, intergroup contact, cultural essentialism, and symbolic threat) to provide a cultural explanation for NATII. Second, we tested the effect of …


Sexual Assault And Health: Understanding The Interplay Of Trauma-Related Appraisals And Physical Health Outcomes, Kerry Lyn Gagnon Aug 2018

Sexual Assault And Health: Understanding The Interplay Of Trauma-Related Appraisals And Physical Health Outcomes, Kerry Lyn Gagnon

Electronic Theses and Dissertations

Women who have been sexually assaulted are at risk for negative mental and physical health outcomes; however, limited research has tested how psychological responses to sexual assault may influence physical health. The present study tested a longitudinal model examining the association between posttrauma appraisals and physical health problems. Drawn from a larger study, the sample included 156 ethnically diverse women who had been sexually assaulted within the last year. The study used cross-lagged panel models to test for reciprocal relationships between posttrauma appraisals and physical health problems over time. A secondary aim of the study was to test whether other …


Motivational Valence Alters Memory Formation Without Altering Exploration Of A Real-Life Spatial Environment, Kimberly S. Chiew, Jordan Hashemi, Lee K. Gans, Laura Lerebours, Nathaniel J. Clement, Mai-Anh T. Vu, Guillermo Sapiro, Nicole E. Heller, R. Alison Adcock Mar 2018

Motivational Valence Alters Memory Formation Without Altering Exploration Of A Real-Life Spatial Environment, Kimberly S. Chiew, Jordan Hashemi, Lee K. Gans, Laura Lerebours, Nathaniel J. Clement, Mai-Anh T. Vu, Guillermo Sapiro, Nicole E. Heller, R. Alison Adcock

Psychology: Faculty Scholarship

Volitional exploration and learning are key to adaptive behavior, yet their characterization remains a complex problem for cognitive science. Exploration has been posited as a mechanism by which motivation promotes memory, but this relationship is not well-understood, in part because novel stimuli that motivate exploration also reliably elicit changes in neuromodulatory brain systems that directly alter memory formation, via effects on neural plasticity. To deconfound interrelationships between motivation, exploration, and memory formation we manipulated motivational state prior to entering a spatial context, measured exploratory responses to the context and novel stimuli within it, and then examined motivation and exploration as …


Vmpfc Activation During A Stressor Predicts Positive Emotions During Stress Recovery, Xi Yang, Katelyn M. Garcia, Youngkyoo Jung, Christopher T. Whitlow, Kateri Mcrae, Christian E. Waugh Mar 2018

Vmpfc Activation During A Stressor Predicts Positive Emotions During Stress Recovery, Xi Yang, Katelyn M. Garcia, Youngkyoo Jung, Christopher T. Whitlow, Kateri Mcrae, Christian E. Waugh

Psychology: Faculty Scholarship

Despite accruing evidence showing that positive emotions facilitate stress recovery, the neural basis for this effect remains unclear. To identify the underlying mechanism, we compared stress recovery for people reflecting on a stressor while in a positive emotional context with that for people in a neutral context. While blood–oxygen-level dependent data were being collected, participants (N = 43) performed a stressful anagram task, which was followed by a recovery period during which they reflected on the stressor while watching a positive or neutral video. Participants also reported positive and negative emotions throughout the task as well as retrospective thoughts …


Recent Advances In The Understanding Of Relationship Communication During Military Deployment, Steven L. Sayers, Galena K. Rhoades Feb 2018

Recent Advances In The Understanding Of Relationship Communication During Military Deployment, Steven L. Sayers, Galena K. Rhoades

Psychology: Faculty Scholarship

In recent decades, there has been a dramatic increase in the ability of service members and their intimate partners to communicate while the service member is deployed to a combat zone. Communication among partners is a crucial aspect of intimate relationships that has been demonstrated to be highly associated with couples’ satisfaction. In addition, it is often cited by unhappy partners as a primary relationship problem. This special section of the Journal of Family Psychology presents five articles investigating deployment communication among service members and their intimate partners. The studies address the content and goals of deployment communication, the relations …


Binocular Rivalry Of Emotional Expressions, Daniel Stephen Lumian Jan 2018

Binocular Rivalry Of Emotional Expressions, Daniel Stephen Lumian

Electronic Theses and Dissertations

A central debate in defining emotional space is whether emotions are organized categorically (e.g., fear, happy, disgust) or continuously (i.e., along the independent dimensions of valence and arousal). Emotional facial expressions are one tool often leveraged in trying to define emotional space. Faces are rich sources of social and emotional information. Faces, like emotions, can be organized in either categorical (e.g., happy, sad) or continuous (e.g., open-closed) ways. Therefore, understanding the relatedness of emotional facial expressions to each other may shed light on the underlying structure of emotions. Binocular rivalry (BR) is a tool which can be leveraged to measure …


Validation Of Minimally-Invasive Sample Collection Methods For Measurement Of Telomere Length, Stephanie A. Stout, Jue Lin, Natalie Hernandez, Elysia Poggi Davis, Elizabeth Blackburn, Judith E. Carroll, Laura M. Glynn Dec 2017

Validation Of Minimally-Invasive Sample Collection Methods For Measurement Of Telomere Length, Stephanie A. Stout, Jue Lin, Natalie Hernandez, Elysia Poggi Davis, Elizabeth Blackburn, Judith E. Carroll, Laura M. Glynn

Psychology: Faculty Scholarship

Objective: The discovery of telomere length (TL) as a biomarker of cellular aging and correlate of age-related disease has generated a new field of research in the biology of healthy aging. Although the most common method of sample collection for TL is venous blood draw, less-invasive DNA collection methods are becoming more widely used. However, how TL relates across tissues derived from these sample collection methods is poorly understood. The current study is the first to characterize the associations in TL across three sample collection methods: venous whole blood, finger prick dried blood spot and saliva.

Methods: TL …


How Socioeconomic Disadvantages Get Under The Skin And Into The Brain To Influence Health Development Across The Lifespan, Pilyoung Kim, Gary W. Evans, Edith Chen, Gregory Miller, Teresa Seeman Nov 2017

How Socioeconomic Disadvantages Get Under The Skin And Into The Brain To Influence Health Development Across The Lifespan, Pilyoung Kim, Gary W. Evans, Edith Chen, Gregory Miller, Teresa Seeman

Psychology: Faculty Scholarship

Socioeconomic disadvantage (SED) has adverse impacts on physical (Adler and Rehkopf 2008; Blair and Raver 2012; Braverman and Egerter 2008; Cohen et al. 2010; Poulton et al. 2002) and psychological (Adler and Rehkopf 2008; Bradley and Corwyn 2002; Grant et al. 2003) health development. SED is similar to low socioeconomic status (SES) which is based on occupation, income, and education or a composite of more than one of these indicators (McLoyd 1998). However, we conceptualize SED more broadly than socioeconomic status to also include subjective perception of social position and contextual indicators of disadvantage, such as neighborhood deprivation. One of …


Family Income, Cumulative Risk Exposure, And White Matter Structure In Middle Childhood, Alexander J. Dufford, Pilyoung Kim Nov 2017

Family Income, Cumulative Risk Exposure, And White Matter Structure In Middle Childhood, Alexander J. Dufford, Pilyoung Kim

Psychology: Faculty Scholarship

Family income is associated with gray matter morphometry in children, but little is known about the relationship between family income and white matter structure. In this paper, using Tract-Based Spatial Statistics, a whole brain, voxel-wise approach, we examined the relationship between family income (assessed by income-to-needs ratio) and white matter organization in middle childhood (N = 27, M = 8.66 years). Results from a non-parametric, voxel-wise, multiple regression (threshold-free cluster enhancement, p < 0.05 FWE corrected) indicated that lower family income was associated with lower white matter organization [assessed by fractional anisotropy (FA)] for several clusters in white matter tracts involved in cognitive and emotional functions including fronto-limbic circuitry (uncinate fasciculus and cingulum bundle), association fibers (inferior longitudinal fasciculus, superior longitudinal fasciculus), and corticospinal tracts. Further, we examined the possibility that cumulative risk (CR) exposure might function as one of the potential pathways by which family income influences neural outcomes. Using multiple regressions, we found lower FA in portions of these tracts, including those found in the left cingulum bundle and left superior longitudinal fasciculus, was significantly related to greater exposure to CR (β = -0.47, p < 0.05 and β = -0.45, p < 0.05).


Enrichment Of Putatively Damaging Rare Variants In The Dyx2 Locus And The Reading-Related Genes Ccdc136 And Flnc, Andrew K. Adams, Shelley D. Smith, Dongnhu T. Truong, Erik G. Willcutt, Richard K. Olson, John C. Defries, Bruce F. Pennington, Jeffrey R. Gruen Nov 2017

Enrichment Of Putatively Damaging Rare Variants In The Dyx2 Locus And The Reading-Related Genes Ccdc136 And Flnc, Andrew K. Adams, Shelley D. Smith, Dongnhu T. Truong, Erik G. Willcutt, Richard K. Olson, John C. Defries, Bruce F. Pennington, Jeffrey R. Gruen

Psychology: Faculty Scholarship

Eleven loci with prior evidence for association with reading and language phenotypes were sequenced in 96 unrelated subjects with significant impairment in reading performance drawn from the Colorado Learning Disability Research Center collection. Out of 148 total individual missense variants identified, the chromosome 7 genes CCDC136 and FLNC contained 19. In addition, a region corresponding to the well-known DYX2 locus for RD contained 74 missense variants. Both allele sets were filtered for a minor allele frequency ≤0.01 and high Polyphen-2 scores. To determine if observations of these alleles are occurring more frequently in our cases than expected by chance in …


General And Emotion-Specific Alterations To Cognitive Control In Women With A History Of Childhood Abuse, Kristen L. Mackiewicz Seghete, Roselinde H. Kaiser, Anne P. Deprince, Marie T. Banich Aug 2017

General And Emotion-Specific Alterations To Cognitive Control In Women With A History Of Childhood Abuse, Kristen L. Mackiewicz Seghete, Roselinde H. Kaiser, Anne P. Deprince, Marie T. Banich

Psychology: Faculty Scholarship

Background

Although limited, the literature suggests alterations in activation of cognitive control regions in adults and adolescents with a history of childhood abuse. The current study examined whether such alterations are increased in the face of emotionally-distracting as compared to emotionally neutral information, and whether such alterations occur in brain regions that exert cognitive control in a more top-down sustained manner or a more bottom-up transient manner.

Methods

Participants were young adult women (ages 23–30): one group with a history of childhood physical or sexual abuse (N = 15) and one with no trauma exposure (N = 17), as assessed …


Abnormal Dendritic Maturation Of Developing Cortical Neurons Exposed To Corticotropin Releasing Hormone (Crh): Insights Into Effects Of Prenatal Adversity?, Megan M. Curran, Curt A. Sandman, Elysia Poggi Davis, Laura M. Glynn, Tallie Z. Baram Jun 2017

Abnormal Dendritic Maturation Of Developing Cortical Neurons Exposed To Corticotropin Releasing Hormone (Crh): Insights Into Effects Of Prenatal Adversity?, Megan M. Curran, Curt A. Sandman, Elysia Poggi Davis, Laura M. Glynn, Tallie Z. Baram

Psychology: Faculty Scholarship

Corticotropin releasing hormone (CRH) produced by the hypothalamus initiates the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body’s stress response. CRH levels typically are undetectable in human plasma, but during pregnancy the primate placenta synthesizes and releases large amounts of CRH into both maternal and fetal circulations. Notably, placental CRH synthesis increases in response to maternal stress signals. There is evidence that human fetal exposure to high concentrations of placental CRH is associated with behavioral consequences during infancy and into childhood, however the direct effects on of the peptide on the human brain are unknown. In this study, we used a …