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Clinical Psychology

PTSD

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Articles 121 - 147 of 147

Full-Text Articles in Psychology

Personality Heterogeneity In Ptsd: Distinct Temperamental And Interpersonal Typologies, Katherine M. Thomas, Christopher J. Hopwood, M. Brent Donnellan, Aidan G. C. Wright, Charles A. Sanislow, Meghan E. Mcdevitt-Murphy, Emily B. Ansell, Carlos M. Grilo, Thomas H. Mcglashan, M. Tracie Shea, John C. Markowitz, Andrew E. Skodol, Mary C. Zanarini, Leslie C. Morey Jan 2014

Personality Heterogeneity In Ptsd: Distinct Temperamental And Interpersonal Typologies, Katherine M. Thomas, Christopher J. Hopwood, M. Brent Donnellan, Aidan G. C. Wright, Charles A. Sanislow, Meghan E. Mcdevitt-Murphy, Emily B. Ansell, Carlos M. Grilo, Thomas H. Mcglashan, M. Tracie Shea, John C. Markowitz, Andrew E. Skodol, Mary C. Zanarini, Leslie C. Morey

Charles A. Sanislow, Ph.D.

Researchers examining personality typologies of posttraumatic stress disorder (PTSD) have consistently identified 3 groups: low pathology, internalizing, and externalizing. These groups have been found to predict functional severity and psychiatric comorbidity. In this study, we employed Latent Profile Analysis to compare this previously established typology, grounded in temperament traits (negative emotionality; positive emotionality; constraint), to a novel typology rooted in interpersonal traits (dominance; warmth) in a sample of individuals with PTSD (n = 155). Using Schedule for Nonadaptive and Adaptive Personality (SNAP) traits to create latent profiles, the 3-group temperament model was replicated. Using Interpersonal Circumplex (IPC) traits to create …


A Latent Profile Analysis Of Posttraumatic Stress And Depressive Symptoms In Adolescents, Shawn A. Wilson Jan 2014

A Latent Profile Analysis Of Posttraumatic Stress And Depressive Symptoms In Adolescents, Shawn A. Wilson

Legacy Theses & Dissertations (2009 - 2024)

This study examines how posttraumatic stress (PTS) and depressive symptoms co-occur during early adolescence. Data for participants in the present study were drawn from the National Survey of Child and Adolescent Well-Being. A latent profile analysis (LPA) was conducted on the data from 818 adolescents aged 11 to 14 who self-identified as Black, Latino, or White. A three-class solution was selected as an optimal fit for the data based on fit indices and ease of interpretation. The LPA indicated that PTS and depressive symptoms tended to co-occur in a dimensional manner, with the classes differing only in terms of the …


Examining The Role Of Unit Cohesion As A Moderator Of The Relationship Between Warfare Exposure And Ptsd, Shaina Gulin Jan 2014

Examining The Role Of Unit Cohesion As A Moderator Of The Relationship Between Warfare Exposure And Ptsd, Shaina Gulin

Theses and Dissertations

The purpose of the current study was to examine the effects of warfare exposure and unit cohesion on posttraumatic stress disorder (PTSD) symptomatology among male and female National Guard and Reserve service members deployed to Iraq or Afghanistan. National Guard and Reserve soldiers and female service members have been shown to be at greatest risk of psychological distress, and thus identification of resiliency factors among this population is worthy of further study. An emerging body of research has identified unit cohesion as a potentially modifiable protective factor against the deleterious effects of warfare exposure; however, such research is in its …


The Dimensions Of Hardiness And Resiliency For Combat Ptsd, Warren Joseph Avery Jan 2014

The Dimensions Of Hardiness And Resiliency For Combat Ptsd, Warren Joseph Avery

Antioch University Full-Text Dissertations & Theses

Research suggests that the personality factor hardiness may aid in resilience to combat PTSD. The need to understand resiliency factors like hardiness becomes more urgent as the depth of the epidemic of combat PTSD among veterans becomes more evident. Hardiness consists of three dimensions: (a) commitment, (b) control, and (c) challenge. This study was designed to explore the relationship between the dimensions of hardiness and combat PTSD in Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) veterans. Participants were contacted through college veterans offices across the nation, and measures were anonymously completed online. Veterans who participated in the study …


Understanding Peritraumatic Dissociation: Evolution-Prepared Dissociation, Tonic Immobility, And Clinical Dissociation, Laura A. Halvorsen Jan 2014

Understanding Peritraumatic Dissociation: Evolution-Prepared Dissociation, Tonic Immobility, And Clinical Dissociation, Laura A. Halvorsen

Antioch University Full-Text Dissertations & Theses

Current literature on the relationship between posttraumatic symptoms and dissociation that occurs during the time of a trauma, or peritraumatic dissociation, appears to be contradictory and inconclusive. Conflicting findings in the empirical literature that disagree on the nature of this association (whether peritraumatic dissociation is a risk factor for PTSD or a neutral or even protective evolutionarily-derived phenomenon) may originate from the lack of conceptual clarity regarding the construct of dissociation, and lack of differentiation between peritraumatic dissociation and dissociation that persists after a traumatic event. This dissertation details a theory for differentiating clusters of peritraumatic dissociation based on distinct …


Ways Of Being In Trauma-Based Society: Discovering The Politics And Moral Culture Of The Trauma Industry Through Hermeneutic Interpretation Of Evidence-Supported Ptsd Treatment Manuals, Sarah Peregrine Lord Jan 2014

Ways Of Being In Trauma-Based Society: Discovering The Politics And Moral Culture Of The Trauma Industry Through Hermeneutic Interpretation Of Evidence-Supported Ptsd Treatment Manuals, Sarah Peregrine Lord

Antioch University Full-Text Dissertations & Theses

One hundred percent of evidence-supported psychotherapy treatments for trauma related disorders involve the therapist learning from and retaining fidelity to a treatment manual. Through a hermeneutic qualitative textual interpretation of three widely utilized evidence-supported trauma treatment manuals, I identified themes that suggested a particular constitution of the contemporary way of being—a traumatized self—and how this traumatized self comes to light through psychotherapeutic practice as described by the manuals. The manuals included: 1) a trauma focused cognitive-behavioral therapy for children; 2) an eye-movement desensitization and reprocessing therapy for adults; and, 3) an early intervention and debriefing therapy series for post-traumatic stress …


The Sexual Assault Severity Scale: A Comprehensive Measure Of Assault Severity, Karyn Crystal Swinson Aug 2013

The Sexual Assault Severity Scale: A Comprehensive Measure Of Assault Severity, Karyn Crystal Swinson

Dissertations

Many studies in the sexual assault literature have found a significant relationship between sexual assault severity and psychological distress, specifically PTSD and suicidality. However, in the current literature, there is an inconsistent and incomplete definition of the construct of assault severity. The present study aims to create a comprehensive self-report questionnaire, called the Sexual Assault Severity Scale (SASS) that includes assault characteristics, such as victim-offender relationship, substance use, and peritraumatic responses, and cognitive variables, such as posttraumatic schema disruptions and coping self-efficacy in the conceptualization of assault severity. Two models evaluating the relationship between assault severity and post assault distress …


Trauma And Post-Traumatic Stress Disorder In Therapeutic Day School Students: Prevalence In This Population And Effective Treatment Programs, Monica Roberts Apr 2013

Trauma And Post-Traumatic Stress Disorder In Therapeutic Day School Students: Prevalence In This Population And Effective Treatment Programs, Monica Roberts

Dissertations

This survey-based, comparative study investigated the percentage of students at a suburban Chicago therapeutic day school who meet criteria for clinically significant levels of PTSD as compared to students in a general education setting. The directional hypothesis was that students placed at therapeutic day schools have a higher prevalence of PTSD than a general population of students. The method used was a survey assessment called the Child PTSD Symptom Scale (CPSS) given to 16 students at a suburban Chicago therapeutic day school. These CPSS scores were analyzed and statistically compared to CPSS scores of an already published study with students …


Neuropsychological, Psychological, And Injury Variables Associated With Post-Traumatic Stress Disorder In Individuals Who Suffered An Electrical Injury, Jana Wingo Jan 2013

Neuropsychological, Psychological, And Injury Variables Associated With Post-Traumatic Stress Disorder In Individuals Who Suffered An Electrical Injury, Jana Wingo

Dissertations

Electrical injury (EI) represents a major form of trauma that can greatly impact the individual cognitively, physically, and emotionally. EI can lead to a variety of cognitive impairments affecting attention, processing speed, motor skills, and memory. Furthermore, EI can lead to a variety of physical impairments from burns to cardiac injury. In addition to other psychiatric disorders, individuals who suffer an EI can eventually develop Post-Traumatic Stress Disorder (PTSD).

This study examined a clinical sample of 143 individuals (86.0% male, 85.3% Caucasian, 44.1% diagnosed with PTSD) who have experienced an EI to determine the factors associated with the development of …


Effects Of Partner Attachment Quality On Ptsd Severity With Combat-Exposed Veterans, Robert Desmond Shura Jan 2013

Effects Of Partner Attachment Quality On Ptsd Severity With Combat-Exposed Veterans, Robert Desmond Shura

Theses, Dissertations and Capstones

Posttraumatic stress disorder (PTSD) as a response to a traumatic stressor encompasses re-experiencing, avoidance, and hyperarousal. Although many individuals will experience a traumatic stressor in the course of a lifetime, only a fraction fully develop PTSD. The purpose of this dissertation was to inform the question as to why some develop PTSD as a response to combat exposure and others do not. This study used the PTSD Checklist – Military Version (PCL-M), Trauma Symptom Inventory - 2 (TSI-2) and the Attachment and Clinical Issues Questionnaire (ACIQ) to test if secure partner attachments predict PTSD severity, anger, and somatization. These models …


The Post-Combat Couple Adjustment Questionnaire: A Preliminary Validation, Valerie Maine Jan 2013

The Post-Combat Couple Adjustment Questionnaire: A Preliminary Validation, Valerie Maine

Antioch University Full-Text Dissertations & Theses

This dissertation presents the results of a psychometric study regarding the preliminary validation of The Post-Combat Couple Adjustment Questionnaire (PCCAQ). This measure was designed to assess post-combat and post-deployment adjustment for male veterans and their female partners. The measure was created using existing literature on veterans, posttraumatic stress disorder (PTSD), and couples. The PCCAQ consists of four domains of couple functioning, including: (a) redefining roles, expectations, and division of household responsibilities; (b) managing strong emotions; (c) abandoning emotional constriction and creating intimacy in relationships; and (d) creating a sense of shared meaning surrounding the deployment experience. The PCCAQ was compared …


Prospective Investigation Of A Ptsd Personality Typology Among Individuals With Personality Disorders, Meghan E. Mcdevitt-Murphy, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, John C. Markowitz, Andrew E. Skodol Jun 2012

Prospective Investigation Of A Ptsd Personality Typology Among Individuals With Personality Disorders, Meghan E. Mcdevitt-Murphy, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, John C. Markowitz, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

This study investigated the replicability of a previously proposed personality typology of posttraumatic stress disorder (PTSD, and explored stability of cluster membership over a 6-month period. Participants with current PTSD (n = 156) were drawn from the Collaborative Longitudinal Personality Disorders Study (CLPS). The CLPS project tracked a large sample of individuals who met criteria for 1 of 4 target diagnoses (borderline, schizotypal, avoidant, and obsessive-compulsive) and a contrast group of individuals who met criteria for depression but no personality disorder. A cluster analysis using scales from the Schedule of Nonadaptive and Adaptive Personality yielded 3 clusters: “internalizing,” “externalizing,” and …


The Impact Of Ptsd On Veterans’ Family Relationships: Mechanisms Of Distress And Available Treatments, Adam D. Lamotte Jan 2012

The Impact Of Ptsd On Veterans’ Family Relationships: Mechanisms Of Distress And Available Treatments, Adam D. Lamotte

Senior Projects Spring 2012

When veterans return home from war with PTSD, the disorder can have detrimental effects on their close family relationships. Researchers have proposed different mechanisms underlying the distress experienced by partners and children of veterans with PTSD in the hopes that these mechanisms can be targeted in treatment. The purpose of this project is to review and synthesize the current literature on these mechanisms of distress, as well as the treatments that have been designed to address them. This review examines several key factors that account for veterans’ relationship distress, including the important factors of intimacy and aggression. Due to the …


Interpersonal Pathoplasticity In The Course Of Major Depression, Nicole M. Cain, Emily B. Ansell, Aidan G. C. Wright, Christopher J. Hopwood, Katherine M. Thomas, Anthony Pinto, John C. Markowitz, Charles A. Sanislow, Mary C. Zanarini, M. Tracie Shea, Leslie C. Morey, Thomas H. Mcglashan, Andrew E. Skodol, Carlos M. Grilo Dec 2011

Interpersonal Pathoplasticity In The Course Of Major Depression, Nicole M. Cain, Emily B. Ansell, Aidan G. C. Wright, Christopher J. Hopwood, Katherine M. Thomas, Anthony Pinto, John C. Markowitz, Charles A. Sanislow, Mary C. Zanarini, M. Tracie Shea, Leslie C. Morey, Thomas H. Mcglashan, Andrew E. Skodol, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

Objective: The identification of reliable predictors of course in major depressive disorder (MDD) has been difficult. Evidence suggests that the co-occurrence of personality pathology is associated with longer time to MDD remission. Interpersonal pathoplasticity, the mutually influencing nonetiological relationship between psychopathology and interpersonal traits, offers an avenue for examining specific personality vulnerabilities that may be associated with depressive course. Method: This study examined 312 participants with and without a cooccurring personality disorder diagnosis who met criteria for a current MDD episode at baseline and who were followed for 10 years in the Collaborative Longitudinal Personality Disorders Study. Results: Latent profile …


Efficacy Of A Cognitive-Behavioral Treatment For Insomnia Among Afghanistan And Iraq (Oef/Oif) Veterans With Ptsd, Margolies Skye Ochsner Nov 2011

Efficacy Of A Cognitive-Behavioral Treatment For Insomnia Among Afghanistan And Iraq (Oef/Oif) Veterans With Ptsd, Margolies Skye Ochsner

Theses and Dissertations

Sleep disturbances are a core and salient feature of PTSD and can maintain or exacerbate associated symptoms. Recent research demonstrates that cognitive-behavioral sleep-focused interventions improve sleep disturbances as well as PTSD symptoms. The present study is a randomized controlled trial comparing Cognitive Behavioral Therapy for Insomnia (CBT-I) to a waitlist control group. Conducted at a Veterans Affairs Medical Center, the study: 1) compared subjective outcome measures of sleep amongst veterans assigned to either a treatment group (CBT-I) or a waitlist control group; (2) examined the influence of the intervention on measures of PTSD, general mood and daytime functioning, comparing veterans …


Long Term Effects Of Chronic Variable Stress Administered During Different Developmental Stages In Mice, Henry Boeh Oct 2011

Long Term Effects Of Chronic Variable Stress Administered During Different Developmental Stages In Mice, Henry Boeh

Dissertations (1934 -)

A number of studies have suggested that the occurrence of past trauma can increase an individual's chance of developing PTSD from a new traumatic experience later in life. Trauma that occurs during childhood appears to have a particularly strong effect on this risk increase. Furthermore, conditioned fear responses have been shown to incubate over extended periods of time in animal models. To further investigate the role these phenomena play in the development of PTSD, this study exposed juvenile and adult mice to 7 days of chronic variable stress (CVS). One month later, a Pavlovian delay fear conditioning procedure was used …


The Association Of Personality Disorders With The Prospective 7-Year Course Of Anxiety Disorders, Emily B. Ansell, Anthony Pinto, Maria O. Edelen, John C. Markowitz, Charles A. Sanislow, Shirley Yen, Mary C. Zanarini, Andrew E. Skodol, M. Tracie Shea, Leslie C. Morey, John G. Gunderson, Thomas H. Mcglashan, Carlos M. Grilo Apr 2011

The Association Of Personality Disorders With The Prospective 7-Year Course Of Anxiety Disorders, Emily B. Ansell, Anthony Pinto, Maria O. Edelen, John C. Markowitz, Charles A. Sanislow, Shirley Yen, Mary C. Zanarini, Andrew E. Skodol, M. Tracie Shea, Leslie C. Morey, John G. Gunderson, Thomas H. Mcglashan, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

Background. This study prospectively examined the natural clinical course of six anxiety disorders over 7 years of follow-up in individuals with personality disorders (PDs) and/or major depressive disorder. Rates of remission, relapse, new episode onset and chronicity of anxiety disorders were examined for specific associations with PDs.

Method. Participants were 499 patients with anxiety disorders in the Collaborative Longitudinal Personality Disorders Study, who were assessed with structured interviews for psychiatric disorders at yearly intervals throughout 7 years of follow-up. These data were used to determine probabilities of changes in disorder status for social phobia (SP), generalized anxiety disorder (GAD), obsessive-compulsive …


The Impact Of Prior Sexual Victimization And Victim Identification On Threat Recognition In A College Sample, Katherine Porter Jun 2010

The Impact Of Prior Sexual Victimization And Victim Identification On Threat Recognition In A College Sample, Katherine Porter

Master's Theses and Doctoral Dissertations

Previous research on sexual assault has demonstrated a pattern of revictimization, in which victims of childhood sexual assault are at an increased risk for adult sexual assault (e.g., Tjaden & Thoennes, 2000). Previous findings indicate that participants with a history of sexual assault take longer to identify and respond to risks (Marx et al., 2001; Soler-Baillo et al., 2005; Wilson et al., 1999), are less likely to respond in assertive ways (VanZile-Tamsen et al., 2005), and are more likely to indicate that they would be compliant in risky sexual situations (Naugle, 1999).

The present study attempted to replicate and expand …


Trajectories Of Ptsd And Substance Use Disorders In A Longitudinal Study Of Personality Disorders, Meghan E. Mcdevitt-Murphy, Gilbert R. Parra, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, Thomas H. Mcglashan, John G. Gunderson, Andrew E. Skodol, John C. Markowitz Nov 2009

Trajectories Of Ptsd And Substance Use Disorders In A Longitudinal Study Of Personality Disorders, Meghan E. Mcdevitt-Murphy, Gilbert R. Parra, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, Thomas H. Mcglashan, John G. Gunderson, Andrew E. Skodol, John C. Markowitz

Charles A. Sanislow, Ph.D.

This study investigated the co-occurrence of posttraumatic stress disorder (PTSD) and substance use disorders (SUDs) in a sample (N 668) recruited for personality disorders and followed longitudinally as part of the Collaborative Longitudinal Personality Disorders Study. The study both examined rates of co-occurring disorders at baseline and temporal relationships between PTSD and substance use disorders over 4 years. Subjects with a lifetime history of PTSD at baseline had significantly higher rates of SUDs (both alcohol and drug) than subjects without PTSD. Latent class growth analysis, a relatively novel approach used to analyze trajectories and identify homogeneous subgroups of participant on …


Attachment: The Antidote To Trauma, Joshua Straub Sep 2009

Attachment: The Antidote To Trauma, Joshua Straub

Faculty Publications and Presentations

Trauma and loss in life are inevitable. And all too often the traumatic experience itself can be enough to paralyze the mental, emotional, and spiritual state of any given person. Unable to interpret the traumatic experience, many instead are left defined by it. Helping clients discern the objective experience and their subjective reactions to it will help free them from the emotions and beliefs that subsequently control their lives. Based on the most relevant attachment theory research and clinical techniques, this workshop teaches the attentional strategies necessary to helping clients overcome trauma.


Prospective Effects Of Sexual Victimization On Ptsd And Problem Drinking, Cynthia J. Najdowski, Sarah E. Ullman Jan 2009

Prospective Effects Of Sexual Victimization On Ptsd And Problem Drinking, Cynthia J. Najdowski, Sarah E. Ullman

Psychology Faculty Scholarship

Posttraumatic stress disorder (PTSD) and problem drinking are common and often co-occurring sequelae experienced by women survivors of adult sexual assault, yet it remains unclear whether survivors drink to cope with PTSD symptoms or whether PTSD symptoms are exacerbated by drinking. Thus, we used a cross-lagged panel design with a large (N = 555), ethnically diverse sample of women assault survivors to determine whether PTSD prospectively led to problem drinking or vice versa. We also examined whether cumulative sexual victimization experiences related to greater PTSD and problem drinking. Structural equation modeling revealed that child sexual abuse was associated with …


The Effect Of Writing As Exposure Therapy On Ptsd Symptoms, Daniel Scott Debrule Aug 2008

The Effect Of Writing As Exposure Therapy On Ptsd Symptoms, Daniel Scott Debrule

Dissertations

The majority of empirically supported treatments for Posttraumatic Stress Disorder involve some form of exposure, which desensitizes an individual to traumarelated information. Theoretical work has suggested that the mechanism of exposure may explain the tendency for writing to lessen symptoms, and empirical evidence of writing and PTSD symptoms suggests that modifying the writing paradigm may result in better symptom relief. The present investigation aimed to compare the efficacy of an exposurebased writing intervention to the standard writing paradigm. A total of 68 undergraduates that were screened for PTSD symptoms were randomly assigned to write about their most severe trauma for …


Ptsd Symptoms And Self-Rated Recovery Among Adult Sexual Assault Survivors: The Effects Of Traumatic Life Events And Psychosocial Variables, Cynthia J. Najdowski, Sarah E. Ullman Jun 2008

Ptsd Symptoms And Self-Rated Recovery Among Adult Sexual Assault Survivors: The Effects Of Traumatic Life Events And Psychosocial Variables, Cynthia J. Najdowski, Sarah E. Ullman

Psychology Faculty Scholarship

Prior research has demonstrated that self-blame is predictive of more PTSD symptoms and poorer recovery (Frazier, 2003; Koss, Figueredo, & Prince, 2002), and perceived control over recovery is associated with less distress (Frazier, 2003) in adult sexual assault (ASA) survivors. A structural equation model was tested to examine the role of traumatic events, self-blame, perceived control over recovery, and coping strategies on PTSD symptoms and self-rated recovery in women ASA survivors. Adaptive coping partially mediated the effects of other traumas, self-blame, and perceived control over recovery on PTSD symptoms, and showed a small positive association with increased PTSD symptoms. As …


Psychophysiological Reactivity To Traumatic And Abandonment Scripts In Borderline Personality And Posttraumatic Stress Disorders: A Preliminary Report, Christian G. Schmahl, Bernet M. Elzinga, Ulrich W. Ebner, Timothy Simms, Charles A. Sanislow, Eric Vermetten, Thomas H. Mcglashan, J. Douglas Bremner Mar 2004

Psychophysiological Reactivity To Traumatic And Abandonment Scripts In Borderline Personality And Posttraumatic Stress Disorders: A Preliminary Report, Christian G. Schmahl, Bernet M. Elzinga, Ulrich W. Ebner, Timothy Simms, Charles A. Sanislow, Eric Vermetten, Thomas H. Mcglashan, J. Douglas Bremner

Charles A. Sanislow, Ph.D.

Borderline personality disorder (BPD) is a highly prevalent and disabling condition linked to early stressors including traumatic abuse and abandonment. While much work has addressed traumatic events in childhood, little is known about the biological sequelae of BPD including how this disorder may be differentiated from other stressrelated disorders such as posttraumatic stress disorder (PTSD). The purpose of this study was to investigate psychophysiological effects of different types of stressful reminders in BPD and in PTSD. Psychophysiological measures including heart rate, skin conductance responses, systolic and diastolic blood pressure in response to standardized neutral scripts, and personalized scripts of traumatic …


Amygdala Hyperreactivity In Borderline Personality Disorder: Implications For Emotional Dysregulation, Nelson H. Donegan, Charles A. Sanislow, Hilary P. Blumberg, Robert K. Fulbright, Cheryl Lacadie, Pawel Skudlarski, John C. Gore, Ingrid R. Olson, Thomas H. Mcglashan, Bruce E. Wexler Nov 2003

Amygdala Hyperreactivity In Borderline Personality Disorder: Implications For Emotional Dysregulation, Nelson H. Donegan, Charles A. Sanislow, Hilary P. Blumberg, Robert K. Fulbright, Cheryl Lacadie, Pawel Skudlarski, John C. Gore, Ingrid R. Olson, Thomas H. Mcglashan, Bruce E. Wexler

Charles A. Sanislow, Ph.D.

BACKGROUND: Disturbed interpersonal relations and emotional dysregulation are fundamental aspects of borderline personality disorder (BPD). The amygdala plays important roles in modulating vigilance and generating negative emotional states and is often abnormally reactive in disorders of mood and emotion. The aim of this study was to assess amygdala reactivity in BPD patients relative to normal control subjects. We hypothesized that amygdala hyperreactivity contributes to hypervigilance, emotional dysregulation, and disturbed interpersonal relations in BPD.

METHODS: Using functional magnetic resonance imaging, we examined neural responses to 20-sec blocks of neutral, happy, sad, and fearful facial expression (or a fixation point) in 15 …


Clinical Features And Impairment In Women With Borderline Personality Disorder (Bpd) With Post-Traumatic Stress Disorder (Ptsd), Bpd Without Ptsd, And Other Personality Disorders With Ptsd, Caron Zlotnick, Dawn M. Johnson, Shirley Yen, Cynthia Battle, Charles A. Sanislow, Andrew E. Skodol, Carlos M. Grilo, Thomas H. Mcglashan, John G. Gunderson, Donna S. Bender, Mary C. Zanarini, M. Tracie Shea Oct 2003

Clinical Features And Impairment In Women With Borderline Personality Disorder (Bpd) With Post-Traumatic Stress Disorder (Ptsd), Bpd Without Ptsd, And Other Personality Disorders With Ptsd, Caron Zlotnick, Dawn M. Johnson, Shirley Yen, Cynthia Battle, Charles A. Sanislow, Andrew E. Skodol, Carlos M. Grilo, Thomas H. Mcglashan, John G. Gunderson, Donna S. Bender, Mary C. Zanarini, M. Tracie Shea

Charles A. Sanislow, Ph.D.

The aims of this study were to examine differences in clinical features, impairment, and types of childhood traumas among women with borderline personality disorder (BPD), women with BPD and posttraumatic stress disorder (PTSD), and those with other personality disorders and PTSD. Using baseline data from the Collaborative Longitudinal Study of Personality Disorders, 186 women were divided into 3 groups (BPD+PTSD, BPD, PTSD), based on structured diagnostic interviews for Axis I and Axis II disorders and compared on selected clinical variables. The additional diagnosis of PTSD in borderline women did not significantly increase the degree of borderline pathology and psychiatric morbidity …


Traumatic Exposure And Posttraumatic Stress Disorder In Borderline, Schizotypal, Avoidant, And Obsessive-Compulsive Personality Disorders: Findings From The Collaborative Longitudinal Personality Disorders Study, Shirley Yen, M. Tracie Shea, Cynthia L. Battle, Dawn M. Johnson, Caron Zlotnick, Regina Dolan-Sewell, Andrew E. Skodol, Carlos M. Grilo, John G. Gunderson, Charles A. Sanislow, Mary C. Zanarini, Donna S. Bender, Jennifer B. Rettew, Thomas H. Mcglashan Jul 2002

Traumatic Exposure And Posttraumatic Stress Disorder In Borderline, Schizotypal, Avoidant, And Obsessive-Compulsive Personality Disorders: Findings From The Collaborative Longitudinal Personality Disorders Study, Shirley Yen, M. Tracie Shea, Cynthia L. Battle, Dawn M. Johnson, Caron Zlotnick, Regina Dolan-Sewell, Andrew E. Skodol, Carlos M. Grilo, John G. Gunderson, Charles A. Sanislow, Mary C. Zanarini, Donna S. Bender, Jennifer B. Rettew, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

The association between trauma and personality disorders (PDs), while receiving much attention and debate, has not been comprehensively examined for multiple types of trauma and PDs. The authors examined data from a multisite study of four PD groups: schizotypal, borderline (BPD), avoidant, and obsessive-compulsive, and a major depression comparison group. Rates of traumatic exposure to specific types of trauma, age of first trauma onset, and rates of posttraumatic stress disorder are compared. Results indicate that BPD participants reported the highest rate of traumatic exposure (particularly to sexual traumas, including childhood sexual abuse), the highest rate of posttraumatic stress disorder, and …