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Mediating Factors Of Perceived Discrimination: Physiological And Affective Markers., Kymberlee O'Brien, Edward Tronick, Celia Moore
Mediating Factors Of Perceived Discrimination: Physiological And Affective Markers., Kymberlee O'Brien, Edward Tronick, Celia Moore
Kymberlee M. O'Brien
Early life adversity influences later health and may be mediated by psychosocial, affective, and physiological stress and immune factors. We report evidence from MIDUS biomarker project (N = 845, age 34-84, M = 55.09, SD = 11.70) confirming the predicted relationship between early adversity and frequency of diagnosed chronic illnesses (M = 2.8, SD =1.2). Specific psychosocial and physiological variables were tested as mediators. Lifetime (M = .95, SD = 1.5) and daily (M = 12.8, SD = 1.2) discrimination, urinary cortisol (M = 1.1, SD = 1.2 ug/dL), IL-6 (M =2.8, SD = 2.8 pg/mL) (all ps<.001), and …