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Biological Psychology

Selected Works

Stress

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Full-Text Articles in Psychology

Mediating Factors Of Perceived Discrimination: Physiological And Affective Markers., Kymberlee O'Brien, Edward Tronick, Celia Moore Jan 2014

Mediating Factors Of Perceived Discrimination: Physiological And Affective Markers., Kymberlee O'Brien, Edward Tronick, Celia Moore

Kymberlee M. O'Brien

Early life adversity influences later health and may be mediated by psychosocial, affective, and physiological stress and immune factors. We report evidence from MIDUS biomarker project (N = 845, age 34-84, M = 55.09, SD = 11.70) confirming the predicted relationship between early adversity and frequency of diagnosed chronic illnesses (M = 2.8, SD =1.2). Specific psychosocial and physiological variables were tested as mediators. Lifetime (M = .95, SD = 1.5) and daily (M = 12.8, SD = 1.2) discrimination, urinary cortisol (M = 1.1, SD = 1.2 ug/dL), IL-6 (M =2.8, SD = 2.8 pg/mL) (all ps<.001), and …


Stress-Induced Attenuation Of Acoustic Startle In Low-Saccharin-Consuming Rats., Clinton Chapman, Mitzi Gonzales, Cameryn Garrett, Nancy Dess Sep 2008

Stress-Induced Attenuation Of Acoustic Startle In Low-Saccharin-Consuming Rats., Clinton Chapman, Mitzi Gonzales, Cameryn Garrett, Nancy Dess

Clinton D Chapman

Exposure to stress can lead to either increased stress vulnerability or enhanced resiliency. Laboratory rats are a key tool in the exploration of basic biobehavioral processes underlying individual differences in the effect of stress on subsequent stressors’ impact. The Occidental low (LoS) and high (HiS) saccharin-consuming rats, which differ in emotional reactivity, are useful in this effort. In the present study, footshock affected acoustic startle amplitude 4h later among LoS but not HiS rats. Surprisingly, shock attenuated startle rather than sensitizing it, a finding not previously reported for male rats exposed to shock. Attenuation was blocked by administering the anxiolytic …