Biological and Physical Anthropology Commons^™

Apolipoprotein-Ε4 Is Associated With Higher Fecundity In A Natural Fertility Population, Benjamin Trumble, Mia Charifson, Tom Kraft, Angela R. Garcia, Daniel K. Cummings, Paul L. Hooper, Amanda J. Lea, Daniel Eid Rodriguez, Stephanie V. Koebele, Kenneth Buetow, Bret Beheim, Riana Minocher, Maguin Gutierrez, Gregory S. Thomas, Margaret Gatz, Jonathan Stieglitz, Caleb E. Finch, Hillard Kaplan, Michael Gurven

ESI Publications

In many populations, the apolipoprotein-ε4 (APOE-ε4) allele increases the risk for several chronic diseases of aging, including dementia and cardiovascular disease; despite these harmful effects at later ages, the APOE-ε4 allele remains prevalent. We assess the impact of APOE-ε4 on fertility and its proximate determinants (age at first reproduction, interbirth interval) among the Tsimane, a natural fertility population of forager-horticulturalists. Among 795 women aged 13 to 90 (20% APOE-ε4 carriers), those with at least one APOE-ε4 allele had 0.3 to 0.5 more children than (ε3/ε3) …

Energetic Costs Of Testosterone In Two Subsistence Populations, Benjamin C. Trumble, Herman Pontzer, Jonathan Stieglitz, Daniel K. Cummings, Brian Wood, Melissa Emery Thompson, David Raichlen, Bret Beheim, Gandhi Yetish, Hillard Kaplan, Michael Gurven

ESI Publications

Objective

Testosterone plays a role in mediating energetic trade-offs between growth, maintenance, and reproduction. Investments in a high testosterone phenotype trade-off against other functions, particularly survival-enhancing immune function and cellular repair; thus only individuals in good condition can maintain both a high testosterone phenotype and somatic maintenance. While these effects are observed in experimental manipulations, they are difficult to demonstrate in free-living animals, particularly in humans. We hypothesize that individuals with higher testosterone will have higher energetic expenditures than those with lower testosterone.

Methods

Total energetic expenditure (TEE) was quantified using doubly labeled water in n = 40 Tsimane forager-horticulturalists …

Reproductive Inequality In Humans And Other Mammals, Cody T. Ross, Paul L. Hooper, Jennifer E. Smith, Adrian V. Jaeggi, Eric Alden Smith, Sergey Gavrilets, Fatema Tuz Zohora, John Ziker, Dimitris Xygalatas, Emily E. Wroblewski, Brian Wood, Bruce Winterhalder, Kai P. Willführ, Aiyana K. Willard, Kara Walker, Christopher Von Rueden, Eckart Voland, Claudia Valeggia, Bapu Vaitla, Samuel Urlacher, Mary Towner, Chun-Yi Sum, Lawrence S. Sugiyama, Karen B. Strier, Kathrine Starkweather, Daniel Major-Smith, Mary Shenk, Rebecca Sear, Edmond Seabright, Ryan Schacht, Brooke Scelza, Shane Scaggs, Jonathan Salerno, Caissa Revilla-Minaya, Daniel Redhead, Anne Pusey, Benjamin Grant Purzycki, Eleanor A. Power, Anne Pisor, Jenni Pettay, Susan Perry, Abigail E. Page, Luis Pacheco-Cobos, Kathryn Oths, Seung-Yun Oh, David Nolin, Daniel Nettle, Cristina Moya, Andrea Bamberg Migliano, Karl J. Mertens, Rita A. Mcnamara, Richard Mcelreath, Siobhan Mattison, Eric Massengill, Frank Marlowe, Felicia Madimenos, Shane Macfarlan, Virpi Lummaa, Roberto Lizarralde, Ruizhe Liu, Melissa A. Liebert, Sheina Lew-Levy, Paul Leslie, Joseph Lanning, Karen Kramer, Jeremy Koster, Hillard S. Kaplan, Bayarsaikhan Jamsranjav, A. Magdalena Hurttado, Kim Hill, Barry Hewlett, Samili Helle, Thomas Headland, Janet Headland, Michael Gurven, Gianluca Grimalda, Russell Greaves, Christopher D. Golden, Irene Godoy, Mhairi Gibson, Claire El Mouden, Mark Dyble, Patricia Draper, Sean Downey, Angelina L. Demarco, Helen Elizabeth Davis, Stefani Crabtree, Carmen Cortez, Heidi Colleran, Emma Cohen, Gregory Clark, Julia Clark, Mark A. Caudell, Chelsea E. Carminito, John Bunce, Adam Boyette, Samuel Bowles, Tami Blumenfield, Bret Beheim, Stephen Beckerman, Quentin Atkinson, Coren Apicella, Nurul Alam, Monique Borgerhoff Mulder

ESI Publications

To address claims of human exceptionalism, we determine where humans fit within the greater mammalian distribution of reproductive inequality. We show that humans exhibit lower reproductive skew (i.e., inequality in the number of surviving offspring) among males and smaller sex differences in reproductive skew than most other mammals, while nevertheless falling within the mammalian range. Additionally, female reproductive skew is higher in polygynous human populations than in polygynous nonhumans mammals on average. This patterning of skew can be attributed in part to the prevalence of monogamy in humans compared to the predominance of polygyny in nonhuman mammals, to the limited …

Atherosclerosis In Indigenous Tsimane: A Contemporary Perspective, Randall C. Thompson, Gregory S. Thomas, Angela D. Neuneubel, Ashna Mahadev, Benjamin Trumble, Edmond Seabright, Daniel K. Cummings, Jonathan Stieglitz, Michael Gurven, Hillard Kaplan

ESI Publications

The Horus and other research teams have found that atherosclerosis is not uncommon in ancient people through the study of their mummified remains (Murphy et al., 2003; Allam et al., 2009, 2011; Thompson et al., 2013, 2014). However, some have postulated that traditional hunter-gatherers are in some ways healthier than modern people and that they had very little atherosclerotic disease (O’Keefe et al., 2010). The aim of this study was to evaluate the burden of atherosclerosis in a population alive today but living a traditional lifestyle similar to that experienced by past populations. This led to the Tsimane Health and …