Social and Behavioral Sciences Commons^™

Segregation Of A Latent High Adiposity Phenotype In Families With A History Of Type 2 Diabetes Mellitus Implicates Rare Obesity-Susceptibility Genetic Variants With Large Effects In Diabetes-Related Obesity, Arthur B. Jenkins, Marijka Batterham, Dorit Samocha-Bonet, Katherine Tonks, Jerry R. Greenfield, Lesley V. Campbell

Faculty of Science, Medicine and Health - Papers: part A

Background We recently reported significantly greater weight gain in non-diabetic healthy subjects with a 1st degree family history (FH+) of type 2 diabetes mellitus (T2DM) than in a matched control group without such history (FH−) during voluntary overfeeding, implying co-inheritance of susceptibilities to T2DM and obesity. We have estimated the extent and mode of inheritance of susceptibility to increased adiposity in FH+.

Methods Normoglycaemic participants were categorised either FH+ (≥1 1st degree relative with T2DM, 50F/30M, age 45±14 (SD) yr) or FH− (71F/51M, age 43±14 yr). Log-transformed anthropometric measurements (height, hip and waist circumferences) and lean, bone and fat mass …

Effects Of Age On Strength Of The Toe Flexor Muscles, Karen J. Mickle, Salih Angin, Gillian Crofts, Julie R. Steele, Christopher Nester

Faculty of Science, Medicine and Health - Papers: part A

Abstract of paper that presented at the Eleventh Footwear Biomechanics Symposium, Natal, Brazil, 2013.

The Effects Of Spending Time Outdoors In Daylight On The Psychosocial Wellbeing Of Older People And Family Carers: A Comprehensive Systematic Review Protocol, Victoria Traynor, Ritin Fernandez, Katherine Caldwell

Faculty of Science, Medicine and Health - Papers: part A

Review question/objective The overall objective of this research is to undertake a systematic review of the effects of spending time outdoors in daylight on the psychosocial wellbeing of older adults and family carers. The specific questions to be addressed are: Which aspects of psychosocial wellbeing are affected by spending time outdoors in daylight in older adults and family carers? To what extent is spending time outdoors in the daylight effective in improving aspects of psychosocial wellbeing in older adults and family carers?

Can Poor Health Literacy Contribute To Potential Side Effects Associated With Buying Over-The-Counter Non-Steroidal Anti-Inflammatory Drugs?, J R. Mullan, Judy Mullan, K M. Weston, A Bonney, C Magee

Faculty of Science, Medicine and Health - Papers: part A

No abstract provided.

Short-Term Effects Of Fish And Fish Oil Consumption On Total And High Molecular Weight Adiponectin Levels In Overweight And Obese Adults, Elizabeth P. Neale, Beverly Muhlhausler, Yasmine C. Probst, Marijka J. Batterham, Francesca Fernandez, Linda C. Tapsell

Faculty of Science, Medicine and Health - Papers: part A

Objective: Fish or fish oil consumption may increase levels of total and high molecular weight (HMW) adiponectin, a hormone associated with anti-inflammatory and insulin-sensitising effects, however it is not known if the effects of the food and supplement are the same. The aim of this study was to compare the effect of consuming fish and fish oil supplements on plasma total and HMW adiponectin concentrations in overweight human participants.

Materials/Methods: 29 overweight and obese participants underwent a two week run-in period, followed by a four week isocaloric dietary intervention which provided 1.8g of long chain omega-3 polyunsaturated fatty acids (LC …

Effects Of Tungsten Addition And Heat Treatment Conditions On Microstructure And Mechanical Properties Of Microalloyed Forging Steels, Jingwei Zhao, Zhengyi Jiang, Chong Soo Lee

Faculty of Engineering and Information Sciences - Papers: Part A

In the present work, the effects of tungsten (W) addition and heat treatment conditions on the microstructure, impact toughness and tensile properties of microalloyed forging steels were studied. Four kinds of microalloyed forging steels were produced by varying W additions (0, 0.5, 1 and 2 wt%). Heat treatment was carried out at temperatures ranging from 840 to 950 °C followed by air and furnace cooling. Mechanical tests were used to evaluate the room temperature Charpy impact and tensile properties. The resulting microstructures were analysed via optical microscope (OM), scanning electron microscope (SEM) and transmission electron microscope (TEM). The results show …

Effects Of Fouling On The Stress-Strain-Degradation Behaviour Of Rail Ballast, Buddhima Indraratna, Nayoma C. Tennakoon, Sanjay Nimbalkar, Cholachat Rujikiatkamjorn

Faculty of Engineering and Information Sciences - Papers: Part A

Ballast is most commonly used as a structural component of rail track due to its high load bearing capacity, resiliency and rapid drainage. However, ballast along coal freight corridors often becomes fouled due to spilling of coal from moving wagons, in addition to further track deterioration attributed to particle breakage and pumping of soft subgrade. Highly fouled ballast needs to be cleaned or replaced to maintain the desired track resiliency, load bearing capacity and the track alignment. In order to identify the risk associated with fouling, it is important to accurately assess the amount of fouling. In this paper, the …

A Model Of The Effects Of Authority On Consensus Formation In Adaptive Networks: Impact On Network Topology And Robustness, Brenton J. Prettejohn, Matthew J. Berryman, Mark D. Mcdonnell

Faculty of Engineering and Information Sciences - Papers: Part A

Opinions of individuals in real social networks are arguably strongly influenced by external determinants, such as the opinions of those perceived to have the highest levels of authority. In order to model this, we have extended an existing model of consensus formation in an adaptive network by the introduction of a parameter representing each agent's level of 'authority' based on their opinion relative to the overall opinion distribution. We found that introducing this model, along with a randomly varying opinion convergence factor, significantly impacts the final state of converged opinions and the number of interactions required to reach that state. …

High-Throughput Particle Manipulation By Hydrodynamic, Electrokinetic, And Dielectrophoretic Effects In An Integrated Microfluidic Chip, Shunbo Li, Ming Li, Kristelle Bougot-Robin, Wenbin Cao, Irene Yeung Chau, Weihua Li, Weijia Wen

Faculty of Engineering and Information Sciences - Papers: Part A

Integrating different steps on a chip for cell manipulations and sample preparation is of foremost importance to fully take advantage of microfluidic possibilities, and therefore make tests faster, cheaper and more accurate. We demonstrated particle manipulation in an integrated microfluidic device by applying hydrodynamic, electroosmotic (EO), electrophoretic (EP), and dielectrophoretic (DEP) forces. The process involves generation of fluid flow by pressure difference, particle trapping by DEP force, and particle redirect by EO and EP forces. Both DC and AC signals were applied, taking advantages of DC EP, EO and AC DEP for on-chip particle manipulation. Since different types of particles …

Numerical Solution Of Stone Column Improved Soft Soil Considering Arching, Clogging And Smear Effects, Buddhima Indraratna, Sudip Basack, Cholachat Rujikiatkamjorn

Faculty of Engineering and Information Sciences - Papers: Part A

Improvement of soft clay deposits by the installation of stone columns is one of the most popular techniques followed worldwide. The stone columns not only act as reinforcingmaterial increasing the overall strength and stiffness of the compressible soft soil, but they also promote consolidation through effective drainage. The analytical and numerical solutions available for ascertaining the response of column-reinforced soil have been developed on the basis of the equal strain hypothesis. For typical surcharge (embankment) loading, the free strain analysis appears to give more realistic results comparable to field data. The paper presents a novel numericalmodel (finite-differencemethod) to analyze the …

Effects Of Feed And Draw Solution Temperature And Transmembrane Temperature Difference On The Rejection Of Trace Organic Contaminants By Forward Osmosis, Ming Xie, William E. Price, Long D. Nghiem, Menachem Elimelech

Faculty of Engineering and Information Sciences - Papers: Part A

The effects of feed and draw solution temperature and transmembrane temperature difference on the rejection of 12 trace organic contaminants (TrOCs) by two forward osmosis (FO) membranes were investigated. The membrane structure parameter (S) and the reverse salt (NaCl) flux selectivity (RSFS) were constant over the temperature range of 20-40 1C, suggesting that within this range, the solution temperature did not significantly influence the membrane polymeric structure. Draw solution properties, including diffusivity, viscosity, and osmotic pressure, played an important role in water and reverse salt (NaCl) flux behaviour and TrOC rejection. Pure water and salt (NaCl) permeability coefficients of the …

The Effects Of Regular Long-Term Cannabis Use On Auditory Mismatch Negativity (Mmn), Lisa-Marie Greenwood, Samantha J. Broyd, Rodney J. Croft, Patricia T. Michie, Juanita Todd, Stuart J. Johnstone, Robyn Murray, Nadia Solowij

Faculty of Social Sciences - Papers (Archive)

Abstract presented at the 3rd Biennial Schizophrenia International Research Conference Florence, Italy 14-18 April 2012

Effects Of Cultural Cognitive Styles On Users Evaluation Of Website Complexity, Tingru Cui, Xinwei Wang, Hock Hai Teo

Faculty of Engineering and Information Sciences - Papers: Part A

The internationalization of websites requires compelling navigation experience for users from diverse cultures. This research investigates the effects of cultural cognitive styles on user perception of website complexity and the subsequent influence on user satisfaction towards the website. More specifically, the website complexity is examined along three dimensions: component, coordinative, and dynamic. Laboratory experiments involving participants from China and United States were used to test the hypotheses. The results showed that the effect of objective complexity on perceived complexity is contingent on cultural cognitive styles. People with holistic and analytic cultural cognitive styles display different perceptions of website complexity. This …

Effects Of Δ9-Tetrahydrocannabinol Administration On Human Encoding And Recall Memory Function: A Pharmacological Fmri Study, Matthijs G. Bossong, Gerry Jager, Hendrika H. Van Hell, Lineke Zuurman, J Martijn Jansma, Mitul A. Mehta, Joop M. A Van Gerven, Rene S. Kahn, Nick F. Ramsey

Faculty of Social Sciences - Papers (Archive)

Deficits in memory function are an incapacitating aspect of various psychiatric and neurological disorders. Animal studies have recently provided strong evidence for involvement of the endocannabinoid (eCB) system in memory function. Neuropsychological studies in humans have shown less convincing evidence but suggest that administration of cannabinoid substances affects encoding rather than recall of information. In this study, we examined the effects of perturbation of the eCB system on memory function during both encoding and recall. We performed a pharmacological MRI study with a placebo-controlled, crossover design, investigating the effects of Δ9-tetrahydrocannabinol (THC) inhalation on associative memory-related brain function in 13 …

Nonlinear Inelastic Behavior Of Circular Concrete-Filled Steel Tubular Slender Beam-Columns With Preload Effects, Vipulkumar Ishvarbhai Patel, Qing Quan Liang, Muhammad N. Hadi

Faculty of Engineering and Information Sciences - Papers: Part A

This paper presents a numerical model based on fiber element formulations for simulating the nonlinear inelastic behavior of eccentrically loaded circular concrete-filled steel tubular (CFST) slender beam-columns with preload effects. Deflections caused by preloads are included in the global analysis of CFST slender beam-columns as initial geometric imperfections. Computational algorithms based on the Müller's method are developed to obtain load-deflection responses of CFST slender beam-columns including preload effects. The accuracy of the numerical model is examined by comparisons of computer solutions with experimental results. The numerical model is utilized to investigate the effects of preloads on the axial load-deflection curves, …

Do Neighbourhoods Have Effects On Wages? A Study Of Migrant Workers In Urban China, Zhiming Cheng, Haining Wang

Faculty of Commerce - Papers (Archive)

Rural-to-urban migrant workers have contributed enormously to the Chinese economy and society in the past three decades. Many of them have concentrated in disadvantaged neighbourhoods and physically and socially suffered from poor residential environment. However it is unclear how the neighbourhoods-as the provision of shelter, social and public service, and community organizing-influence migrant workers' labour market outcomes. To fill this gap, this paper researches the way in which urban neighbourhoods have affected migrant workers' wages. Factors such as housing quality, social interaction and trust, and neighbourhood organization and participation were examined. Results show that five of eight neighbourhood characteristics had …

Environmental Effects Of Ozone Depletion And Its Interactions With Climate Change: Progress Report, 2011, Anthony L. Andrady, Pieter J. Aucamp, Amy T. Austin, Alkiviadis F. Bais, Carlos L. Ballare, Lars Olof Bjorn, Janet F. Bornman, Martyn Caldwell, Anthony P. Cullen, David J. Erickson, Frank R. De Gruijl, Donat-P Hader, Walter Helbling, Mohammad Ilyas, Janice Longstreth, Robyn Lucas, Richard L. Mckenzie, Sasha Madronich, Mary Norval, Nigel D. Paul, Halim Redhwi, Sharon Robinson, Min Shao, Keith R. Solomon, Barbara Sulzberger, Yukio Takizawa, Xiaoyan Tang, Ayako Torikai, Jan C. Van Der Leun, Craig Williamson, Stephen R. Wilson, Robert C. Worrest, Richard G. Zepp

Faculty of Science, Medicine and Health - Papers: part A

The parties to the Montreal Protocol are informed by three panels of experts. One of these is the Environmental Effects Assessment Panel (EEAP), which deals with two focal issues. The first focus is the effects of increased UV radiation on human health, animals, plants, biogeochemistry, air quality, and materials. The second focus is on interactions between UV radiation and global climate change and how these may affect humans and the environment. When considering the effects of climate change, it has become clear that processes resulting in changes in stratospheric ozone are more complex than believed previously. As a result of …

Radiocarbon Bomb Spike Reveals Biological Effects Of Antarctic Climate Change, Laurence J Clarke, Sharon A. Robinson, Quan Hua, David J. Ayre, David Fink

Faculty of Science - Papers (Archive)

The Antarctic has experienced major changes in temperature, wind speed and stratospheric ozone levels during thelast 50 years. However, until recently continental Antarctica appeared to be little impacted by climate warming, thusbiological changes were predicted to be relatively slow. Detecting the biological effects of Antarctic climate changehas been hindered by the paucity of long-term data sets, particularly for organisms that have been exposed to thesechanges throughout their lives. We show that radiocarbon signals are preserved along shoots of the dominant Antarcticmoss flora and use these to determine accurate growth rates over a period of several decades, allowing us toexplore the …

Effects Of Atmospheric Light Scattering On Spectroscopic Observations Of Greenhouse Gases From Space: Validation Of Ppdf-Based Co 2 Retrievals From Gosat, Sergey Oshchepkov, Andrey Bril, Tatsuya Yokota, Isamu Morino, Yukio Yoshida, Tsuneo Matsunaga, Dmitry Belikov, Debra Wunch, Paul Wennberg, Geoffrey Toon, Christopher O'Dell, André Butz, Sandrine Guerlet, Austin Cogan, Hartmut Boesch, Nawo Eguchi, Nicholas Deutscher, David Griffith, Ronald Macatangay, Justus Notholt, Ralf Sussmann, Markus Rettinger, Vanessa Sherlock, John Robinson, Esko Kyro, Pauli Heikkinen, Dietrich G. Feist, Tomoo Nagahama, Nikolay Kadygrov, Shamil Maksyutov, Osamu Uchino, Hiroshi Watanabe

Faculty of Science - Papers (Archive)

This report describes a validation study of Greenhouse gases Observing Satellite (GOSAT) data processing using ground-based measurements of the Total Carbon Column Observing Network (TCCON) as reference data for column-averaged dry air mole fractions of atmospheric carbon dioxide (X CO2). We applied the photon path length probability density function method to validate X CO2 retrievals from GOSAT data obtained during 22months starting from June 2009. This method permitted direct evaluation of optical path modifications due to atmospheric light scattering that would have a negligible impact on ground-based TCCON measurements but could significantly affect gas retrievals when observing reflected sunlight from …

Are Competitive Effects Of Native Species On An Invader Mediated By Water Availability?, Tanya J. Mason, Kristine French, Ken Russell

Faculty of Science - Papers (Archive)

Question: Climate change processes could influence the dynamics of biotic interactions such as plant competition, especially in response to disturbance phenomena such as invasional processes. Are competitive effects of native species on an invadermediated bywater availability?

Location: Glasshouse facility, New SouthWales, Australia.

Methods: We constructed competitive hierarchies for a representative suite of species from coastal dune communities that have been invaded by the Asteraceae shrub, bitou (Chrysanthemoides monilifera subsp. rotundata). We used a comparative phytometer approach, where the invader species was grown with or without a suite of native species in glasshouse trials. This was used to construct competition hierarchies …

Independent Effects Of Local And Global Binocular Disparity On The Perceived Convexity Of Stereoscopically Presented Faces In Scenes, Harold Matthews, Harold Hill, Stephen Palmisano

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.

Effects Of Feed Solution Characteristics And Membrane Fouling On N-Nitrosamine Rejection By Reverse Osmosis Membranes, Takahiro Fujioka, Long D. Nghiem, Stuart Khan, James Mcdonald, Yvan Poussade, Jörg Drewes

Faculty of Engineering and Information Sciences - Papers: Part A

Augmentation of potable water sources with reclaimed municipal wastewater is an option of increasing importance for water security in regions and countries where severe water stress occurs. Consequently, the presence of emerging trace contaminants in reclaimed water has been recognised as a critical issue due to their potential adverse health effects. Notable examples of these trace organic chemicals include N-nitrosodimethylamine (NDMA) and several other N-nitrosamines.

The Schizophrenia Susceptibility Gene Neuregulin 1 Modulates Tolerance To The Effects Of Canabinoids, Aurelie Boucher, Glenn E. Hunt, Jacques Micheau, Xu-Feng Huang, Iain Mcgregor, Tim Karl, Jonathon Arnold

Faculty of Health and Behavioural Sciences - Papers (Archive)

Cannabis increases the risk of schizophrenia in genetically vulnerable individuals. In this study we aim to show that the schizophrenia susceptibility gene neuregulin 1 (Nrg1) modulates the development of tolerance to cannabinoids in mice. Nrg1 heterozygous (HET) and wild-type (WT) mice were treated daily for 15 d with the synthetic analogue of D9-tetrahydrocannabinol, CP55,940 (0.4 mg/kg). We measured the impact of this exposure on locomotor activity, anxiety, prepulse inhibition (PPI), body temperature and FosB/DFosB immunohistochemistry. Tolerance to CP55,940-induced hypothermia and locomotor suppression developed more rapidly in Nrg1 HET mice than WT mice. Conversely in the light-dark test, while tolerance to …

Effects Of Dairy Products On Crohn's Disease Symptoms Are Influenced By Fat Content And Disease Location But Not Lactose Content Or Disease Activity Status In A New Zealand Population, Deborah Nolan, Linda C. Tapsell, Rong Hu, Dug Yeo Han, Lynnette Ferguson

Faculty of Health and Behavioural Sciences - Papers (Archive)

Background Dairy products have been perceived as having the potential to cause adverse effects in individuals with Crohn’s disease (CD) and are often avoided, potentially increasing the risk of osteoporosis and related morbidity associated with inadequate dietary calcium intake. Objective To evaluate the self-reported effects of dairy products on CD symptoms and to determine whether these effects differed between types of dairy products consumed and disease state or location. Design Secondary analysis of dietary survey and clinical data from participants in the Genes and Diet in Inflammatory Bowel Disease study based in Auckland, New Zealand. Subjects/setting One hundred and sixty-five …

Effects Of A Single Dose Of Exenatide On Appetite, Gut Hormones, And Glucose Homeostasis In Adults With Prader-Willi Syndrome, Lisa Sze, Louise Purtell, Arthur Jenkins, Georgina Loughnan, Ellie Smith, Herbert Herzog, Amanda Sainsbury, Katharine Steinbeck, Lesley V. Campbell, Alexander Viardot

Faculty of Health and Behavioural Sciences - Papers (Archive)

Context: Prader-Willi syndrome (PWS) is associated with hyperphagia and obesity, without effective pharmacological treatment. Exenatide, recently developed for treatment of type 2 diabetes, induces appetite suppression and weight loss with common side effects. Objective: The objective of the study was to investigate the initial safety and effectiveness of exenatide in adult PWS subjects compared with obese controls (OBESE). Design, Setting, Patients, and Intervention: Eight PWS and 11 OBESE patients underwent standardized meal studies after a single sc injection of 10 g exenatide or placebo in a single-blinded, crossover design. Main Outcome Measures: Glucose, insulin, C-peptide, glucagon, peptide YY (PYY; total)/PYY …

Specific Electromagnetic Effects Of Microwave Radiation On Escherichia Coli, Yury Shamis, Alex Taube, Natasa Mitik-Dineva, Rodney Croft, Russell J. Crawford, Elena P. Ivanova

Faculty of Health and Behavioural Sciences - Papers (Archive)

The present study investigated the effects of microwave (MW) radiation on Escherichia coli applied under a sub-lethal temperature. The experiments were conducted at a frequency of 18 GHz and performed at a temperature below 40oC to avoid the thermal degradation of bacterial cells during exposure. The absorbed power was calculated to be 1500 kW/m3 and the electric field was determined to be 300 V/m. Both values were theoretically confirmed using CST Microwave Studio 3D Electromagnetic Simulation Software. As a negative control, E. coli cells were also thermally heated up to temperatures up to 40oC using Peltier Plate heating. Scanning Electron …

Effects Of Salinity And Sand Content On Liquid Limit And Hydraulic Conductivity, Behzad Fatahi, Mohammad Hadi Khabbaz, Sudip Basack

Faculty of Engineering and Information Sciences - Papers: Part A

Soil conditions of construction sites have become worse than ever due to the overpopulation in the metropolitan areas throughout the world. Likewise, the prevention of environmental risks due to individual activities is one of the most important subjects in the geo-environmental problems. Saline soils may induce several problems in geotechnical engineering projects such as infrastructure embankments, road construction and clay liners. Effect of the various concentrations of sodium chloride (NaCl) on several different soils including bentonite, kaolinite and fine sand mixtures has been evaluated. In addition, influence of salinity and the period of submergence on the hydraulic conductivity of soil …

Evidence For Involvement Of The Insula In The Psychotropic Effects Of Thc In Humans: A Double-Blind, Randomized Pharmacological Mri Study, Hendrika H. Van Hell, Matthijs G. Bossong, Gerry Jager, Gert Kristo, Matthias J. P Van Osch, Fernando Zelaya, Rene S. Kahn, Nick F. Ramsey

Faculty of Social Sciences - Papers (Archive)

The main reason for recreational use of cannabis is the 'high', the primary psychotropic effect of Δ⁹-tetrahydrocannabinol (THC). This psychoactive compound of cannabis induces a range of subjective, physical and mental reactions. The effect on heart rate is pronounced and complicates bloodflow-based neuroimaging of psychotropic effects of THC. In this study we investigated the effects of THC on baseline brain perfusion and activity in association with the induction of 'feeling high'. Twenty-three subjects participated in a pharmacological MRI study, where we applied arterial spin labelling (ASL) to measure perfusion, and resting-state functional MRI to assess blood oxygen level-dependent …

Examining The Protective Effects Of Brand Equity In The Keepin' It Real Substance Use Prevention Curriculum, Jeong Kyu Lee, Michael L. Hecht

Faculty of Social Sciences - Papers (Archive)

While branding appears to be an effective health prevention strategy, it is less clear how successful brands have protective effects. To better understand the role of branding in health prevention and promotion, it is necessary to examine how the persuasive mechanisms of branding function in health campaigns (e.g., modeling socially desirable behaviors). Using a cross-sectional data (N = 709), the current study uncovered the mechanisms explaining branding's effects on adolescent substance use in a school-based substance use intervention, keepin' it REAL (kiR) curriculum. Consistent with our predictions, a confirmatory factor analysis suggested that kiR brand equity had a higher-order, multidimensional …

Effects Of A Brief Cognitive Intervention Aimed At Communicating The Negative Reinforcement Explanation For Smoking On Relevant Cognitions And Urges To Smoke, Mairtin S. Mcdermott, Theresa M. Marteau, Peter Hajek

Faculty of Engineering and Information Sciences - Papers: Part A

Introduction:The aim of the current study was to assess the impact of an intervention aimed at communicating the negative reinforcement explanation for smoking, a set of ideas derived from popular self-help books, upon participants' cognitions and urges to smoke. Methods: Smokers (n = 205) undergoing standard stop-smoking treatment were randomised to receive either the experimental intervention, a brief intervention aimed at communicating the explanation or a control intervention, a video on the health risks of smoking. Outcomes were participants' acceptance of the negative reinforcement explanation for smoking, positive outcome expectations for smoking, self-efficacy and urges to smoke reported at one …