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Full-Text Articles in Social and Behavioral Sciences

Chinese Digital Platform Companies’ Expansion In The Belt And Road Countries, Yujia He Mar 2024

Chinese Digital Platform Companies’ Expansion In The Belt And Road Countries, Yujia He

Patterson School of Diplomacy and International Commerce Faculty Publications

The emergence of digital platforms is shifting the digital economy toward a platform economy, and Chinese platform-based businesses like Alibaba, Tencent, and JD are increasingly expanding in the Global South. Alongside this, the Chinese government has been promoting digital economy collaboration with emerging markets through high-level engagement under the banner of the Belt and Road Initiative (BRI) and its digital economy component the Digital Silk Road (DSR). Despite significant market interest and policy attention, grounded empirical analysis of Chinese digital platforms’ expansion within Belt and Road Initiative countries is scarce. This study employs a mixed-methods approach, drawing on both quantitative …


The Geopolitics Of Infrastructuralized Platforms: The Case Of Alibaba, Hong Shen, Yujia He Oct 2022

The Geopolitics Of Infrastructuralized Platforms: The Case Of Alibaba, Hong Shen, Yujia He

Patterson School of Diplomacy and International Commerce Faculty Publications

Contemporary digital platforms have become increasingly infrastructuralized, and started to raise geopolitical tensions with their global expansion. Amidst the heightened geopolitical competition between the US and China, the growing power of Chinese infrastructuralized platforms has made them the center of recent geopolitical dynamics. Drawing from an exploratory case study, this paper discusses Alibaba, one of the most prominent Chinese Internet giants, as an infrastructuralized platform, and highlights its geopolitical struggles. Often perceived as an e-commerce company, Alibaba has become ‘infrastructuralized’: its now-massive digital empire has moved beyond e-commerce, expanding into almost every aspect of China’s and global digital economy such …


Chinese-Backed Fintech Lending Boom: How Did Indonesia Respond?, Angela Tritto, Yujia He, Victoria Amanda Junaedi Jul 2022

Chinese-Backed Fintech Lending Boom: How Did Indonesia Respond?, Angela Tritto, Yujia He, Victoria Amanda Junaedi

Diplomacy and International Commerce Reports

Peer-to-peer (P2P) online lending has the potential to boost innovation and financial inclusion in emerging markets, yet it can also incur investment and borrower-related risks, such as privacy breaches.

Driven by regulation control in China, Chinese investments flocked to Indonesia, causing a rapid expansion of online lending platforms.

Similar to what happened in China prior to the regulatory crackdown, the P2P lending boom in Indonesia saw a rise in unethical and illegal business practices. The government responded by creating new regulations and institutions to mitigate risks without stifling the potential for financial inclusion.

A proactive approach towards monitoring and regulating …


Urban Utopia Or Pipe Dream? Examining Chinese-Invested Smart City Development In Southeast Asia, Yujia He, Angela Tritto Jul 2022

Urban Utopia Or Pipe Dream? Examining Chinese-Invested Smart City Development In Southeast Asia, Yujia He, Angela Tritto

Patterson School of Diplomacy and International Commerce Faculty Publications

With increasing public–private partnership and international cooperation in smart city development across the Global South, Chinese firms are poised to take advantage of growing business opportunities, a situation that few studies have examined. This empirical case study of the Forest City, a Chinese-invested greenfield smart city project in Iskandar Malaysia, begins to fill that gap. This megaproject represents the coming together of overlapping economic development interests of the local authorities and the profit motivations of the Chinese investor. However, the project’s use of the ‘smart city’ discourse contrasts with the reality of limited technology adoption. Its visibility and considerable socio-economic …


Gender And Remittances: Lived Experiences Of Women In Oaxaca, Mexico, Araby Smyth Jan 2022

Gender And Remittances: Lived Experiences Of Women In Oaxaca, Mexico, Araby Smyth

Theses and Dissertations--Geography

This dissertation project analyzes the ways that migration and remittances, the money that migrants send to people in their place of origin, intersect with the political and social dynamics in an Indigenous community in the Isthmus of Tehuantepec region of Oaxaca, Mexico. Drawing on 16 months of ethnographic fieldwork, which included semi-structured interviews and participant observation alongside historical archival investigation, this dissertation examines the following questions: What international organizations, national government, and private sector policies govern remittances? How does Indigenous collective work and communal governance shape remittance management? How do the responsibilities of family members shift with migration and how …


The Isolated As The Revolutionary: How “Leftover” Men In China Challenge Heteronormativity, Ruwen Chang Jan 2022

The Isolated As The Revolutionary: How “Leftover” Men In China Challenge Heteronormativity, Ruwen Chang

Theses and Dissertations--Gender and Women's Studies

In contemporary China, demographers estimate that 30 million men are single because there are simply not enough women in the Chinese population, and the 2020 Chinese census shows that there are 34.9 million more men than women. These men are called guanggun, which can be directly translated to “bare sticks/branches,” a slur that indicates a lack of marriage and sex. In this project, I demonstrate that guanggun’s singlehood marks them as the marginalized at the intersection of heteronormativity, patriarchy, globalizing capitalism, and pronatalist governmentality. In a highly heteronormative and patrilineal culture, guanggun are branded as abnormal/incomplete. However, because …


Chinese-Invested Smart City Development In Southeast Asia - How Resilient Are Urban Megaprojects In The Age Of Covid-19?, Yujia He, Angela Tritto Jul 2021

Chinese-Invested Smart City Development In Southeast Asia - How Resilient Are Urban Megaprojects In The Age Of Covid-19?, Yujia He, Angela Tritto

Diplomacy and International Commerce Reports

Smart cities are emerging as major engines for deploying intelligent systems to enhance urban development and contribute to the UN 2030 Sustainable Development Goals (UN SDG). In developing economies facing rapid urbanization and technological change, new cities are being built with smart technologies and ideals, complete with business districts and residential, retail, entertainment, medical, education facilities to entice businesses and talents to relocate. Governments tout the potential of such “greenfield” smart cities for innovation and sustainability. Yet such urban megaprojects are often extremely expensive, prompting governments to partner with private players such as property developers, investors, and tech firms to …


Beyond The Great Power Competition Narrative: Exploring Labor Politics And Resistance Behind Ai Innovation In China, Yujia He, Hong Shen Jul 2021

Beyond The Great Power Competition Narrative: Exploring Labor Politics And Resistance Behind Ai Innovation In China, Yujia He, Hong Shen

Patterson School of Diplomacy and International Commerce Faculty Publications

No abstract provided.


Understanding Struggles And Triumphs Of Widows In Central Nigeria: A Path To Communication And Economic Empowerment, Meredith Annette Garrison Jan 2021

Understanding Struggles And Triumphs Of Widows In Central Nigeria: A Path To Communication And Economic Empowerment, Meredith Annette Garrison

Theses and Dissertations--Communication

One in ten African women age 15 or older are widows. Approximately 8 million widows live in Nigeria with many living in extreme poverty. Throughout the nation, widows are subjected to physical and psychological harm from their families and communities following the deaths of their husbands. Women are marginalized across Nigeria, but widowed women often experience ostracization and oppression that leads to poverty. Most widows rely on informal business and petty trading to survive but these ventures typically only bring in less than a $1 a day for a family. This dissertation critically examined the situation of widows in a …


Building Quality? Migration, Suzhi, And Subaltern Masculinity In The Shanghai Construction Industry, Leif Johnson Jan 2021

Building Quality? Migration, Suzhi, And Subaltern Masculinity In The Shanghai Construction Industry, Leif Johnson

Theses and Dissertations--Geography

This doctoral dissertation providesa novel perspective on the everyday lives of construction workers in urban China, demonstrating the underpinnings of urban infrastructure and citizenship policy in affective and gendered relations surrounding the construction industry. Drawing on 18 months of ethnographic fieldwork in Shanghai, China, this dissertation makes a series of three related arguments: First, focusing on the role that migrant labor plays in the construction of urban infrastructure in Shanghai, I argue that the physical existence of infrastructure itself is inextricably tied to systems that govern rural-urban migration across China. Second, building from the Chinese concept of suzhi as both …


Statelessness And Contested Sovereignty In The Middle East: The United States, Palestinian Refugees, The Muslim Brotherhood, Syrian Ethnic Minorities, And The Early Cold War, 1945 – 1954, John Perry Jan 2021

Statelessness And Contested Sovereignty In The Middle East: The United States, Palestinian Refugees, The Muslim Brotherhood, Syrian Ethnic Minorities, And The Early Cold War, 1945 – 1954, John Perry

Theses and Dissertations--History

This dissertation examines the significance of America’s interactions with stateless actors. It argues that it was groups such as the Muslim Brotherhood, Palestine’s refugees, and ethnic minorities, not the U.S. and Soviet governments, nor the state governments of the region, which dictated how the Cold War unfolded in the Middle East. These groups transformed the policy decisions, strategies, and alliances of both native regimes and the superpowers. Traditionally, historians have looked at the global politics of the Cold War through the lens of state-to-state relations. How have state governments interacted with each other and how did this influence the strategies …


Beyond Extractivism And Governmentality: The Postneoliberal State, Development, And The Circulation Of Oil Rents Among Indigenous Peoples In The Ecuadorian Amazon, Karla Monserrath Encalada-Falconí Jan 2020

Beyond Extractivism And Governmentality: The Postneoliberal State, Development, And The Circulation Of Oil Rents Among Indigenous Peoples In The Ecuadorian Amazon, Karla Monserrath Encalada-Falconí

Theses and Dissertations--Anthropology

This dissertation explores the experiences of an indigenous community from the Northern Ecuadorian Amazon during the implementation of extractivism, development, and redistributive projects. Drawing on twenty months of ethnographic fieldwork in the community of Playas del Cuyabeno and in Quito, the capital of Ecuador, I question the common assumption that indigenous peoples radically reject extractivism and state-imposed modernizing agendas. In contrast, this study shows how indigenous peoples negotiate resource extraction in their territories and navigate the partial failures of postneoliberal redistribution and the contradictory agendas of economic development projects—specifically the aim of the postneoliberal Ecuadorian government’s project to redistribute rents …


Prevalence And Correlates Of Diagnosed And Undiagnosed Hypertension In The Indigenous Kuna Population Of Panamá, Daniel R. Hanna, Rebekah J. Walker, Brittany L. Smalls, Jennifer A. Campbell, Aprill Z. Dawson, Leonard E. Egede Jun 2019

Prevalence And Correlates Of Diagnosed And Undiagnosed Hypertension In The Indigenous Kuna Population Of Panamá, Daniel R. Hanna, Rebekah J. Walker, Brittany L. Smalls, Jennifer A. Campbell, Aprill Z. Dawson, Leonard E. Egede

Center for Health Services Research Faculty Publications

Background: To determine the prevalence of hypertension and investigate sociodemographic correlates in an indigenous Kuna community living on the San Blas islands of Panama.

Methods: Data was collected from adults using a paper-based survey using a cross sectional study design. Blood pressure was measured, and hypertension defined at two cut-points: 130/80 mmHg and 140/90 mmHg. Individuals with undiagnosed hypertension had a blood pressure measurement that indicated hypertension, however, the individual had not been told by a doctor they had hypertension. Whereas individuals with diagnosed hypertension had been told by a healthcare provider that they had hypertension. Univariate tests compared diagnosed …


Living In Gang-Controlled Neighborhoods: Impacts On Electoral And Nonelectoral Participation In El Salvador, Abby Córdova Apr 2019

Living In Gang-Controlled Neighborhoods: Impacts On Electoral And Nonelectoral Participation In El Salvador, Abby Córdova

Political Science Faculty Publications

Gangs’ territorial control affects the lives of residents in thousands of neighborhoods across Latin America, particularly in northern Central American countries. I argue that gang dominance constrains the ability of neighborhood residents to mobilize politically and consequently resist gang violence through institutionalized channels. Living in gang-controlled neighborhoods results in fewer incentives and opportunities to make political elites accountable for one’s personal safety. Even residents who have already experienced crime firsthand are discouraged from turning to politics as a strategy to change the status quo. My theoretical insights identify mechanisms through which gangs’ neighborhood control affects nonelectoral and electoral participation. To …


Setting The Stage: Resident Experiences With Enforcement, Rescue And Spectacle In Lampedusa, Elisa Sperandio Jan 2019

Setting The Stage: Resident Experiences With Enforcement, Rescue And Spectacle In Lampedusa, Elisa Sperandio

Theses and Dissertations--Geography

Located 127 miles from the shores of Sicily and only 70 from Tunisia, the island of Lampedusa is home to a population of 6000. Residents are largely reliant on a centuries-old fishing economy, a booming tourism industry and, most recently, the sustainment of a complex apparatus of border enforcement. Since the early 2000s, with the hardening of the southern border of Italy and the European Union, a multitude of actors have converged to Lampedusa: from migrants, to agents of enforcement, to NGO personnel, along with journalists, researchers and tourists. In this thesis, I center the experiences of island residents to …


Evaluation Of A Palliative Care Initiative On The African Continent: Responsibly Improving Access To Pain Treatment, J. Spencer Hirschi Jan 2019

Evaluation Of A Palliative Care Initiative On The African Continent: Responsibly Improving Access To Pain Treatment, J. Spencer Hirschi

MPA/MPP/MPFM Capstone Projects

The African continent today faces a crisis of inadequate palliative care, in spite of the growing level of suffering of its citizens who are faced with debilitating diseases and injuries. Much of this problem stems from deeply ingrained attitudes towards opioids: while the American continent grapples with the effects of opioid overprescribing, physicians trained in Africa are taught that opioids are inappropriate for virtually all scenarios, and therefore they come to fear and avoid their use or simply remain untrained on them altogether. Patients fail to advocate for themselves out of submission to the doctor’s authority, governments remain apathetic to …


Can Maternity Benefits Have Long-Term Effects On Childbearing? Evidence From Soviet Russia, Olga Malkova Oct 2018

Can Maternity Benefits Have Long-Term Effects On Childbearing? Evidence From Soviet Russia, Olga Malkova

Economics Faculty Publications

This paper quantifies the effects of Russia’s 1981 expansion in maternity benefits on completed childbearing. The program provided one year of partially paid parental leave and a small cash transfer upon a child’s birth. I exploit the program’s two-stage implementation and find evidence that women had more children as a result of the program. Fertility rates rose immediately by 8.2% over twelve months. The increase in fertility rates not only persisted for the ten-year duration of the program, but it reflected large increases in higher-order births to older women who already had children before the program started.


Measuring Women's Empowerment In Sub-Saharan Africa: Exploratory And Confirmatory Factor Analyses Of The Demographic And Health Surveys, Ibitola O. Asaolu, Halimatou Alaofè, Jayleen K. L. Gunn, Akosua K. Adu, Amanda J. Monroy, John E. Ehiri, Mary H. Hayden, Kacey C. Ernst Jun 2018

Measuring Women's Empowerment In Sub-Saharan Africa: Exploratory And Confirmatory Factor Analyses Of The Demographic And Health Surveys, Ibitola O. Asaolu, Halimatou Alaofè, Jayleen K. L. Gunn, Akosua K. Adu, Amanda J. Monroy, John E. Ehiri, Mary H. Hayden, Kacey C. Ernst

Epidemiology and Environmental Health Faculty Publications

Background: Women's status and empowerment influence health, nutrition, and socioeconomic status of women and their children. Despite its benefits, however, research on women's empowerment in Sub-Saharan Africa (SSA) is limited in scope and geography. Empowerment is variably defined and data for comparison across regions is often limited. The objective of the current study was to identify domains of empowerment from a widely available data source, Demographic and Health Surveys, across multiple regions in SSA.

Methods: Demographic and Health Surveys from nineteen countries representing four African regions were used for the analysis. A total of 26 indicators across different dimensions (economic, …


Going Beyond The "T" In "Ctc": Social Practices As Care In Community Technology Centers, David Nemer Jun 2018

Going Beyond The "T" In "Ctc": Social Practices As Care In Community Technology Centers, David Nemer

Information Science Faculty Publications

Community technology center (CTC) is a term usually associated with facilities that provide free or affordable computer and internet access, and sometimes training, to people in underserved communities. Despite the large number of studies done on CTCs, the literature has focused primarily on the use of ICTs as the main, if not the only, activity in these centers. When it comes to addressing social concerns, the literature has often seen them as an outcome of ICT use. It does not highlight CTCs as an inherent and important social space that helps to tackle social issues. Thus, in this study, I …


School Day Extension And Female Labor Supply: The Case Of The Dominican Republic, Patricia Mones Jan 2018

School Day Extension And Female Labor Supply: The Case Of The Dominican Republic, Patricia Mones

MPA/MPP/MPFM Capstone Projects

Since 2012 the Dominican education authorities have been transitioning the schools from a four-hour to an eight-hour per day schedule. As time spent in school is a proxy of childcare, the extension translates into a childcare cost reduction for participating families. Considering the long-studied relationship between childcare costs and mothers’ labor decisions, this study explores the effect of the implementation of the new school schedule on female labor supply both to the extensive and to the intensive margins in the Dominican Republic. Results suggest higher shares of students attending the new schedule within a municipal district are associated with a …


Influence Of Dietary Salt Knowledge, Perceptions, And Beliefs On Consumption Choices After Stroke In Uganda, Martin N. Kaddumukasa, Elly Katabira, Martha Sajatovic, Svetlana Pundik, Mark Kaddumukasa, Larry B. Goldstein Dec 2017

Influence Of Dietary Salt Knowledge, Perceptions, And Beliefs On Consumption Choices After Stroke In Uganda, Martin N. Kaddumukasa, Elly Katabira, Martha Sajatovic, Svetlana Pundik, Mark Kaddumukasa, Larry B. Goldstein

Neurology Faculty Publications

Background

Previous research on Uganda's poststroke population revealed that their level of dietary salt knowledge did not lead to healthier consumption choices.

Purpose

Identify barriers and motivators for healthy dietary behaviors and evaluate the understanding of widely accepted salt regulation mechanisms among poststroke patients in Uganda.

Methods

Convergent parallel mixed methods triangulation design comprised a cross-sectional survey (n = 81) and 8 focus group discussions with 7-10 poststroke participants in each group. We assessed participant characteristics and obtained insights into their salt consumption attitudes, perceptions, and knowledge. Qualitative responses were analyzed using an inductive approach with thematic analytic procedures. Relationships …


Interleukin-6 (Il-6) Rs1800796 And Cyclin Dependent Kinase Inhibitor (Cdkn2a/Cdkn2b) Rs2383207 Are Associated With Ischemic Stroke In Indigenous West African Men, Rufus Akinyemi, Donna K. Arnett, Hemant K. Tiwari, Bruce Ovbiagele, Fred Sarfo, Vinodh Srinivasasainagendra, Marguerite Ryan Irvin, Abiodun Adeoye, Rodney T. Perry, Albert Akpalu, Carolyn Jenkins, Lukman Owolabi, Reginald Obiako, Kolawole Wahab, Emmanuel Sanya, Morenikeji Komolafe, Michael Fawale, Philip Adebayo, Godwin Osaigbovo, Taofiki Sunmonu, Paul Olowoyo, Innocent Chukwuonye, Yahaya Obiabo, Onoja Akpa, Sylvia Melikam, Raelle Saulson, Raj Kalaria, Adesola Ogunniyi, Mayowa Owolabi Aug 2017

Interleukin-6 (Il-6) Rs1800796 And Cyclin Dependent Kinase Inhibitor (Cdkn2a/Cdkn2b) Rs2383207 Are Associated With Ischemic Stroke In Indigenous West African Men, Rufus Akinyemi, Donna K. Arnett, Hemant K. Tiwari, Bruce Ovbiagele, Fred Sarfo, Vinodh Srinivasasainagendra, Marguerite Ryan Irvin, Abiodun Adeoye, Rodney T. Perry, Albert Akpalu, Carolyn Jenkins, Lukman Owolabi, Reginald Obiako, Kolawole Wahab, Emmanuel Sanya, Morenikeji Komolafe, Michael Fawale, Philip Adebayo, Godwin Osaigbovo, Taofiki Sunmonu, Paul Olowoyo, Innocent Chukwuonye, Yahaya Obiabo, Onoja Akpa, Sylvia Melikam, Raelle Saulson, Raj Kalaria, Adesola Ogunniyi, Mayowa Owolabi

Epidemiology and Environmental Health Faculty Publications

Background—Inherited genetic variations offer a possible explanation for the observed peculiarities of stroke in sub – Saharan African populations. Interleukin–6 polymorphisms have been previously associated with ischemic stroke in some non-African populations.

Aim—Herein we investigated, for the first time, the association of genetic polymorphisms of IL-6 and CDKN2A- CDKN2B and other genes with ischemic stroke among indigenous West African participants in the Stroke Investigative Research and Education Network (SIREN) Study.

Methods—Twenty-three previously identified single nucleotide polymorphisms (SNPs) in 14 genes of relevance to the neurobiology of ischemic stroke were investigated. Logistic regression models adjusting for known …


Prevalence And Prognostic Features Of Ecg Abnormalities In Acute Stroke: Findings From The Siren Study Among Africans, Abiodun M. Adeoye, Okechukwu S. Ogah, Bruce Ovbiagele, Rufus Akinyemi, Vincent Shidali, Francis Agyekum, Akinyemi Aje, Oladimeji Adebayo, Joshua O. Akinyemi, Philip Kolo, Lambert Tetteh Appiah, Henry Iheonye, Uwanuruochi Kelechukwu, Amusa Ganiyu, Taiwo O. Olunuga, Onoja Akpa, Ojo Olakanmi Olagoke, Fred Stephen Sarfo, Kolawole Wahab, Samuel Olowookere, Adekunle Fakunle, Albert Akpalu, Philip B. Adebayo, Kwadwo Nkromah, Joseph Yaria, Philip Ibinaiye, Godwin Ogbole, Aridegbe Olumayowa, Sulaiman Lakoh, Benedict Calys-Tagoe, Donna K. Arnett Jun 2017

Prevalence And Prognostic Features Of Ecg Abnormalities In Acute Stroke: Findings From The Siren Study Among Africans, Abiodun M. Adeoye, Okechukwu S. Ogah, Bruce Ovbiagele, Rufus Akinyemi, Vincent Shidali, Francis Agyekum, Akinyemi Aje, Oladimeji Adebayo, Joshua O. Akinyemi, Philip Kolo, Lambert Tetteh Appiah, Henry Iheonye, Uwanuruochi Kelechukwu, Amusa Ganiyu, Taiwo O. Olunuga, Onoja Akpa, Ojo Olakanmi Olagoke, Fred Stephen Sarfo, Kolawole Wahab, Samuel Olowookere, Adekunle Fakunle, Albert Akpalu, Philip B. Adebayo, Kwadwo Nkromah, Joseph Yaria, Philip Ibinaiye, Godwin Ogbole, Aridegbe Olumayowa, Sulaiman Lakoh, Benedict Calys-Tagoe, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Background

Africa has a growing burden of stroke with associated high morbidity and a 3-year fatality rate of 84%. Cardiac disease contributes to stroke occurrence and outcomes, but the precise relationship of abnormalities as noted on a cheap and widely available test, the electrocardiogram (ECG), and acute stroke outcomes have not been previously characterized in Africans.

Objectives

The study assessed the prevalence and prognoses of various ECG abnormalities among African acute stroke patients encountered in a multisite, cross-national epidemiologic study.

Methods

We included 890 patients from Nigeria and Ghana with acute stroke who had 12-lead ECG recording within first 24 …


Exploring Overlaps Between The Genomic And Environmental Determinants Of Lvh And Stroke: A Multicenter Study In West Africa, Abiodun M. Adeoye, Bruce Ovbiagele, Philip Kolo, Lambert Appiah, Akinyemi Aje, Oladimeji Adebayo, Fred Sarfo, Joshua Akinyemi, Gregory Adekunle, Francis Agyekum, Vincent Shidali, Okechukwu Ogah, Dan Lackland, Mulugeta Gebregziabher, Donna K. Arnett, Hemant K. Tiwari, Rufus Akinyemi, Ojo Olakanmi Olagoke, Ayodipupo Sikiru Oguntade, Taiwo Olunuga, Kelechi Uwanruochi, Carolyn Jenkins, Patrick Adadey, Henry Iheonye, Lukman Owolabi, Reginald Obiako, Samuel Akinjopo, Kevin Armstrong, Albert Akpalu, Adekunle Fakunle Jun 2017

Exploring Overlaps Between The Genomic And Environmental Determinants Of Lvh And Stroke: A Multicenter Study In West Africa, Abiodun M. Adeoye, Bruce Ovbiagele, Philip Kolo, Lambert Appiah, Akinyemi Aje, Oladimeji Adebayo, Fred Sarfo, Joshua Akinyemi, Gregory Adekunle, Francis Agyekum, Vincent Shidali, Okechukwu Ogah, Dan Lackland, Mulugeta Gebregziabher, Donna K. Arnett, Hemant K. Tiwari, Rufus Akinyemi, Ojo Olakanmi Olagoke, Ayodipupo Sikiru Oguntade, Taiwo Olunuga, Kelechi Uwanruochi, Carolyn Jenkins, Patrick Adadey, Henry Iheonye, Lukman Owolabi, Reginald Obiako, Samuel Akinjopo, Kevin Armstrong, Albert Akpalu, Adekunle Fakunle

Epidemiology and Environmental Health Faculty Publications

Background

Whether left ventricular hypertrophy (LVH) is determined by similar genomic and environmental risk factors with stroke, or is simply an intermediate stroke marker, is unknown.

Objectives

We present a research plan and preliminary findings to explore the overlap in the genomic and environmental determinants of LVH and stroke among Africans participating in the SIREN (Stroke Investigative Research and Education Network) study.

Methods

SIREN is a transnational, multicenter study involving acute stroke patients and age-, ethnicity-, and sex-matched control subjects recruited from 9 sites in Ghana and Nigeria. Genomic and environmental risk factors and other relevant phenotypes for stroke and …


Single-Trait And Multi-Trait Genome-Wide Association Analyses Identify Novel Loci For Blood Pressure In African-Ancestry Populations, Jingjing Liang, Thu H. Le, Digna R. Velez Edwards, Bamidele O. Tayo, Kyle J. Gaulton, Jennifer A. Smith, Yingchang Lu, Richard A. Jensen, Guanjie Chen, Lisa R. Yanek, Karen Schwander, Salman M. Tajuddin, Tamar Sofer, Wonji Kim, James Kayima, Colin A. Mckenzie, Ervin Fox, Michael A. Nalls, J. Hunter Young, Yan V. Sun, Jacqueline M. Lane, Sylvia Cechova, Jie Zhou, Hua Tang, Myriam Fornage, Solomon K. Musani, Heming Wang, Juyoung Lee, Adebowale Adeyemo, Albert W. Dreisbach, Donna K. Arnett May 2017

Single-Trait And Multi-Trait Genome-Wide Association Analyses Identify Novel Loci For Blood Pressure In African-Ancestry Populations, Jingjing Liang, Thu H. Le, Digna R. Velez Edwards, Bamidele O. Tayo, Kyle J. Gaulton, Jennifer A. Smith, Yingchang Lu, Richard A. Jensen, Guanjie Chen, Lisa R. Yanek, Karen Schwander, Salman M. Tajuddin, Tamar Sofer, Wonji Kim, James Kayima, Colin A. Mckenzie, Ervin Fox, Michael A. Nalls, J. Hunter Young, Yan V. Sun, Jacqueline M. Lane, Sylvia Cechova, Jie Zhou, Hua Tang, Myriam Fornage, Solomon K. Musani, Heming Wang, Juyoung Lee, Adebowale Adeyemo, Albert W. Dreisbach, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify novel susceptibility loci for blood pressure and hypertension in people of African ancestry, we performed both single and multiple-trait genome-wide association analyses. We analyzed 21 genome-wide association studies comprised of 31,968 individuals of African ancestry, and validated our results with additional 54,395 individuals from multi-ethnic studies. These analyses identified nine loci with eleven independent variants which reached genome-wide significance (P < 1.25×10−8) for either systolic and …


Discovery And Fine-Mapping Of Adiposity Loci Using High Density Imputation Of Genome-Wide Association Studies In Individuals Of African Ancestry: African Ancestry Anthropometry Genetics Consortium, Maggie C. Y. Ng, Mariaelisa Graff, Yingchang Lu, Anne E. Justice, Poorva Mudgal, Ching-Ti Liu, Kristin Young, Lisa R. Yanek, Mary F. Feitosa, Mary K. Wojczynski, Kristin Rand, Jennifer A. Brody, Brian E. Cade, Latchezar Dimitrov, Qing Duan, Xiuqing Guo, Leslie A. Lange, Michael A. Nalls, Hayrettin Okut, Salman M. Tajuddin, Bamidele O. Tayo, Sailaja Vedantam, Jonathan P. Bradfield, Guanjie Chen, Wei-Min Chen, Alessandra Chesi, Marguerite R. Irvin, Badri Padhukasahasram, Jennifer A. Smith, Wei Zheng, Donna K. Arnett Apr 2017

Discovery And Fine-Mapping Of Adiposity Loci Using High Density Imputation Of Genome-Wide Association Studies In Individuals Of African Ancestry: African Ancestry Anthropometry Genetics Consortium, Maggie C. Y. Ng, Mariaelisa Graff, Yingchang Lu, Anne E. Justice, Poorva Mudgal, Ching-Ti Liu, Kristin Young, Lisa R. Yanek, Mary F. Feitosa, Mary K. Wojczynski, Kristin Rand, Jennifer A. Brody, Brian E. Cade, Latchezar Dimitrov, Qing Duan, Xiuqing Guo, Leslie A. Lange, Michael A. Nalls, Hayrettin Okut, Salman M. Tajuddin, Bamidele O. Tayo, Sailaja Vedantam, Jonathan P. Bradfield, Guanjie Chen, Wei-Min Chen, Alessandra Chesi, Marguerite R. Irvin, Badri Padhukasahasram, Jennifer A. Smith, Wei Zheng, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Genome-wide association studies (GWAS) have identified > 300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African ancestry genomes. We performed large scale meta-analyses and replications in up to 52,895 individuals for BMI and up to 23,095 individuals for WHRadjBMI from the African Ancestry Anthropometry Genetics Consortium (AAAGC) using 1000 Genomes phase 1 imputed GWAS to improve coverage of both common and low frequency variants in the low linkage disequilibrium African ancestry genomes. In the sex-combined analyses, we identified …


Environmental Challenges In Central And Eastern Europe, Bernhard Hennig Mar 2017

Environmental Challenges In Central And Eastern Europe, Bernhard Hennig

Superfund Research Center Faculty Publications

No abstract provided.


A Study On Change And Determinants Of South Koreans' Perceptions Of Unification, Seong Koo Ham Jan 2017

A Study On Change And Determinants Of South Koreans' Perceptions Of Unification, Seong Koo Ham

MPA/MPP/MPFM Capstone Projects

South Koreans’ interest in and aspirations for unification have decreased recently. This decrease of desires for unification is one of the obstacles to achieve unification. This study analyzes the change of South Koreans’ perceptions of unification and examines various factors that affect those perceptions toward unification. I use unification perceptions survey data from 2007 to 2014 collected by the Institute for Peace and Unification Studies Seoul National University.

The dependent variables of this study are perceptions of the necessity of unification and the possibility of unification. Independent variables are classified into four types. They are expected benefit factors, the political …


No Such State As Palestine: Notions Of Home And The State In Palestinian Relationships With Palestine, Osama A. Abdl-Haleem Jan 2017

No Such State As Palestine: Notions Of Home And The State In Palestinian Relationships With Palestine, Osama A. Abdl-Haleem

Theses and Dissertations--Geography

There is no such state as Palestine. But nearly 70 years after the termination of the British mandate for Palestine and the creation of the state of Israel, Palestine remains a home for the Palestinian. It is an identity not dependent on the existence of a Palestinian state, nor arrested by the presence of an Israeli one. Palestinians have a home relationship with Palestine, where home is a sense of belonging that comes from within, that isn’t earned and given, but personal and chosen, even while it is communal. Home is a self-determined relationship of person to place. The relationships …


Politics Below The Surface: A Political Ecology Of Mineral Rights And Land Tenure Struggles In Appalachia And The Andes, Lindsay Shade Jan 2017

Politics Below The Surface: A Political Ecology Of Mineral Rights And Land Tenure Struggles In Appalachia And The Andes, Lindsay Shade

Theses and Dissertations--Geography

This dissertation examines how confusion and lack of access to information about subsurface property rights facilitates the rapid acquisition of mineral rights by mining interests, leaving those who live 'above the surface' to contend with complicated corporate and bureaucratic apparatuses. The research focuses on the first proposed state-run large scale mining project in Ecuador, believed to contain copper ores, and on the natural gas hydrofracking industry in three counties in north central West Virginia. Qualitative and visual methods, including mapping, are employed to determine (i.) how the geography of subsurface ownership patterns is changing, (ii.) links between changes in subsurface …