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A Semiparametric Model Selection Criterion With Applications To The Marginal Structural Model, M. Alan Brookhart, Mark J. Van Der Laan
A Semiparametric Model Selection Criterion With Applications To The Marginal Structural Model, M. Alan Brookhart, Mark J. Van Der Laan
U.C. Berkeley Division of Biostatistics Working Paper Series
Estimators for the parameter of interest in semiparametric models often depend on a guessed model for the nuisance parameter. The choice of the model for the nuisance parameter can affect both the finite sample bias and efficiency of the resulting estimator of the parameter of interest. In this paper we propose a finite sample criterion based on cross validation that can be used to select a nuisance parameter model from a list of candidate models. We show that expected value of this criterion is minimized by the nuisance parameter model that yields the estimator of the parameter of interest with …
Why Prefer Double Robust Estimates? Illustration With Causal Point Treatment Studies, Romain Neugebauer, Mark J. Van Der Laan
Why Prefer Double Robust Estimates? Illustration With Causal Point Treatment Studies, Romain Neugebauer, Mark J. Van Der Laan
U.C. Berkeley Division of Biostatistics Working Paper Series
In point treatment marginal structural models with treatment A, outcome Y and covariates W, causal parameters can be estimated under the assumption of no unobserved confounders. Three estimates can be used: the G-computation, Inverse Probability of Treatment Weighted (IPTW) or Double Robust (DR) estimates. The properties of the IPTW and DR estimates are known under an assumption on the treatment mechanism that we name "Experimental Treatment Assignment" (ETA) assumption. We show that the DR estimating function is unbiased when the ETA assumption is violated if the model used to regress Y on A and W is correctly specified. The practical …