Statistical Methodology Commons^™

Statistical Computational Topology And Geometry For Understanding Data, Joshua Lee Mike

Doctoral Dissertations

Here we describe three projects involving data analysis which focus on engaging statistics with the geometry and/or topology of the data.

The first project involves the development and implementation of kernel density estimation for persistence diagrams. These kernel densities consider neighborhoods for every feature in the center diagram and gives to each feature an independent, orthogonal direction. The creation of kernel densities in this realm yields a (previously unavailable) full characterization of the (random) geometry of a dataspace or data distribution.

In the second project, cohomology is used to guide a search for kidney exchange cycles within a kidney paired …

Statistical Methods On Risk Management Of Extreme Events, Zijing Zhang

Doctoral Dissertations

The goal of the dissertation is the investigation of financial risk analysis methodologies, using the schemes for extreme value modeling as well as techniques from copula modeling. Extreme value theory is concerned with probabilistic and statistical questions re- lated to unusual behavior or rare events. The subject has a rich mathematical theory and also a long tradition of applications in a variety of areas. We are interested in its application in risk management, with a focus on estimating and forcasting the Value-at-Risk of financial time series data. Extremal data are inherently scarce, thus making inference challenging. In order to obtain …

Statistical Methods For High Dimensional Data Arising From Large Epidemiological Studies, Hui Xu

Doctoral Dissertations

In this thesis, we propose statistical models for addressing commonly encountered data types and study designs in large epidemiologic investigations aimed at understanding the molecular basis of complex disorders. The motivating applications come from diverse disease areas in Women's Health, including the study of type II diabetes in the Women's Health Initiative (WHI), invasive breast cancer in the Nurses' Health Study and the study of the metabolomic underpinnings of cardiovascular disease in the WHI. We have also put significant effort into making the implementation of the proposed methods accessible through freely available, user-friendly software packages in R. The first chapter …

Inference From Network Data In Hard-To-Reach Populations, Isabelle Beaudry

Doctoral Dissertations

The objective of this thesis is to develop methods to make inference about the prevalence of an outcome of interest in hard-to-reach populations. The proposed methods address issues specific to the survey strategies employed to access those populations. One of the common sampling methodology used in this context is respondent-driven sampling (RDS). Under RDS, the network connecting members of the target population is used to uncover the hidden members. Specialized techniques are then used to make inference from the data collected in this fashion. Our first objective is to correct traditional RDS prevalence estimators and their associated uncertainty estimators for …