Statistical Methodology Commons^™

Comparison Of Hazard, Odds And Risk Ratio In The Two-Sample Survival Problem, Benedict P. Dormitorio

Dissertations

Cox proportional hazards is the standard method for analyzing treatment efficacy when time-to-event data is available. In the absence of time-to-event, investigators may use logistic regression which only requires relative frequencies of events, or Poisson regression which requires only interval-summarized frequency tables of time-to-event. When event frequencies are used instead of time-to-events, does it always result in a loss in power?

We investigate the relative performance of the three methods. In particular, we compare the power of tests based on the respective effect-size estimates (1)hazard ratio (HR), (2)odds ratio (OR), and (3)risk ratio (RR). We use a variety of survival …

Robust Residuals And Diagnostics In Autoregressive Time Series, Kirk W. Anderson

Dissertations

One of the goals of model diagnostics is outlier detection. In particular, we would like to use the residuals, appropriately standardized, to “flag” outliers. Hopefully, our (robust) procedure has yielded a fit that resists undue influence by outlying points, while simultaneously drawing attention to these interesting points via residual analysis. In this study we consider several different methods of standardizing the residuals resulting from autoregression. A large sample approximation for the variance of rank-based first order autoregressive time series residuals is developed. This provides studentized residuals, specific to the time series model and estimation procedure. Simulation studies are presented that …

New Statitstical Methods For The Estimation Of The Mean And Standard Deviation From Normally Distributed Censored Samples, Abou El-Makarim Abd El-Alim Aboueissa

Dissertations

The main objective of this dissertation is to estimate the mean /x and standard deviation cr of a normal population from left-censored samples. We have developed new methods for calculating estimates for the mean and standard deviation of a normal population from left-censored samples. Some of these methods based on traditional estimating procedures. A new method of obtaining the Cohen maximum likelihood estimates for fx and cr without the aid of an auxiliary table will be introduced. This new method will be used to extend Cohen table of estimating the Cohen A-parameter that is required for calculating the maximum likelihood …