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Full-Text Articles in Statistical Methodology

Compare And Contrast Maximum Likelihood Method And Inverse Probability Weighting Method In Missing Data Analysis, Scott Sun May 2021

Compare And Contrast Maximum Likelihood Method And Inverse Probability Weighting Method In Missing Data Analysis, Scott Sun

Mathematical Sciences Technical Reports (MSTR)

Data can be lost for different reasons, but sometimes the missingness is a part of the data collection process. Unbiased and efficient estimation of the parameters governing the response mean model requires the missing data to be appropriately addressed. This paper compares and contrasts the Maximum Likelihood and Inverse Probability Weighting estimators in an Outcome-Dependendent Sampling design that deliberately generates incomplete observations. WE demonstrate the comparison through numerical simulations under varied conditions: different coefficient of determination, and whether or not the mean model is misspecified.


Non-Parametric Estimation Of Roc Curves In The Absence Of A Gold Standard, Xiao-Hua Zhou, Pete Castelluccio, Chuan Zhou Jul 2004

Non-Parametric Estimation Of Roc Curves In The Absence Of A Gold Standard, Xiao-Hua Zhou, Pete Castelluccio, Chuan Zhou

UW Biostatistics Working Paper Series

In evaluation of diagnostic accuracy of tests, a gold standard on the disease status is required. However, in many complex diseases, it is impossible or unethical to obtain such the gold standard. If an imperfect standard is used as if it were a gold standard, the estimated accuracy of the tests would be biased. This type of bias is called imperfect gold standard bias. In this paper we develop a maximum likelihood (ML) method for estimating ROC curves and their areas of ordinal-scale tests in the absence of a gold standard. Our simulation study shows the proposed estimates for the …