Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Microarrays
Program Of Gene Transcription For A Single Differentiating Cell Type During Sporulation In Bacillus Subtilis, Patrick Eichenberger, Masaya Fujita, Shane T. Jensen, Erin M. Conlon, David Z. Rudner, Stephanie T. Want, Caitlin Ferguson, Koki Haga, Txutomu Sato, Jun S. Liu, Richard Losick
Program Of Gene Transcription For A Single Differentiating Cell Type During Sporulation In Bacillus Subtilis, Patrick Eichenberger, Masaya Fujita, Shane T. Jensen, Erin M. Conlon, David Z. Rudner, Stephanie T. Want, Caitlin Ferguson, Koki Haga, Txutomu Sato, Jun S. Liu, Richard Losick
Erin M. Conlon
Asymmetric division during sporulation by Bacillus subtilis generates a mother cell that undergoes a 5-h program of differentiation. The program is governed by a hierarchical cascade consisting of the transcription factors: σE, σK, GerE, GerR, and SpoIIID. The program consists of the activation and repression of 383 genes. The σE factor turns on 262 genes, including those for GerR and SpoIIID. These DNA-binding proteins downregulate almost half of the genes in the σE regulon. In addition, SpoIIID turns on ten genes, including genes involved in the appearance of σK. Next, σK activates 75 additional genes, including that for GerE. This …
The Program Of Gene Transcription For A Single Differentiating Cell Type During Sporulation In Bacillus Subtilis, Patrick Eichenberger, Masaya Fujita, Shane T. Jensen, Erin M. Conlon, David Z. Rudner, Stephanie T. Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S. Liu, Richard Losick
The Program Of Gene Transcription For A Single Differentiating Cell Type During Sporulation In Bacillus Subtilis, Patrick Eichenberger, Masaya Fujita, Shane T. Jensen, Erin M. Conlon, David Z. Rudner, Stephanie T. Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S. Liu, Richard Losick
Erin M. Conlon
Asymmetric division during sporulation by Bacillus subtilis generates a mother cell that undergoes a 5-h program of differentiation. The program is governed by a hierarchical cascade consisting of the transcription factors: σE, σK, GerE, GerR, and SpoIIID. The program consists of the activation and repression of 383 genes. The σE factor turns on 262 genes, including those for GerR and SpoIIID. These DNA-binding proteins downregulate almost half of the genes in the σE regulon. In addition, SpoIIID turns on ten genes, including genes involved in the appearance of σK. Next, σK activates 75 additional genes, including that for GerE. This …