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Articles 1 - 4 of 4
Full-Text Articles in Applied Statistics
Robust Optimization Of Biological Protocols, Patrick Flaherty, Ronald W. Davis
Robust Optimization Of Biological Protocols, Patrick Flaherty, Ronald W. Davis
Mathematics and Statistics Department Faculty Publication Series
When conducting high-throughput biological experiments, it is often necessary to develop a protocol that is both inexpensive and robust. Standard approaches are either not cost-effective or arrive at an optimized protocol that is sensitive to experimental variations. Here, we describe a novel approach that directly minimizes the cost of the protocol while ensuring the protocol is robust to experimental variation. Our approach uses a risk-averse conditional value-at-risk criterion in a robust parameter design framework. We demonstrate this approach on a polymerase chain reaction protocol and show that our improved protocol is less expensive than the standard protocol and more robust …
Spatial And Temporal Correlations Of Freeway Link Speeds: An Empirical Study, Piotr J. Rachtan
Spatial And Temporal Correlations Of Freeway Link Speeds: An Empirical Study, Piotr J. Rachtan
Masters Theses 1911 - February 2014
Congestion on roadways and high level of uncertainty of traffic conditions are major considerations for trip planning. The purpose of this research is to investigate the characteristics and patterns of spatial and temporal correlations and also to detect other variables that affect correlation in a freeway setting. 5-minute speed aggregates from the Performance Measurement System (PeMS) database are obtained for two directions of an urban freeway – I-10 between Santa Monica and Los Angeles, California. Observations are for all non-holiday weekdays between January 1st and June 30th, 2010. Other variables include traffic flow, ramp locations, number of lanes and the …
Determinants Of Health Care Use Among Rural, Low-Income Mothers And Children: A Simultaneous Systems Approach To Negative Binomial Regression Modeling, Swetha Valluri
Masters Theses 1911 - February 2014
The determinants of health care use among rural, low-income mothers and their children were assessed using a multi-state, longitudinal data set, Rural Families Speak. The results indicate that rural mothers’ decisions regarding health care utilization for themselves and for their child can be best modeled using a simultaneous systems approach to negative binomial regression. Mothers’ visits to a health care provider increased with higher self-assessed depression scores, increased number of child’s doctor visits, greater numbers of total children in the household, greater numbers of chronic conditions, need for prenatal or post-partum care, development of a new medical condition, and …
Dynamic Model Pooling Methodology For Improving Aberration Detection Algorithms, Brenton J. Sellati
Dynamic Model Pooling Methodology For Improving Aberration Detection Algorithms, Brenton J. Sellati
Masters Theses 1911 - February 2014
Syndromic surveillance is defined generally as the collection and statistical analysis of data which are believed to be leading indicators for the presence of deleterious activities developing within a system. Conceptually, syndromic surveillance can be applied to any discipline in which it is important to know when external influences manifest themselves in a system by forcing it to depart from its baseline. Comparing syndromic surveillance systems have led to mixed results, where models that dominate in one performance metric are often sorely deficient in another. This results in a zero-sum trade off where one performance metric must be afforded greater …