Applied Statistics Commons^™

Best Probable Subset: A New Method For Reducing Data Dimensionality In Linear Regression, Elieser Nodarse

FIU Electronic Theses and Dissertations

Regression is a statistical technique for modeling the relationship between a dependent variable Y and two or more predictor variables, also known as regressors. In the broad field of regression, there exists a special case in which the relationship between the dependent variable and the regressor(s) is linear. This is known as linear regression.

The purpose of this paper is to create a useful method that effectively selects a subset of regressors when dealing with high dimensional data and/or collinearity in linear regression. As the name depicts it, high dimensional data occurs when the number of predictor variables is far …

Computational Analysis Of Large-Scale Trends And Dynamics In Eukaryotic Protein Family Evolution, Joseph Boehm Ahrens

FIU Electronic Theses and Dissertations

The myriad protein-coding genes found in present-day eukaryotes arose from a combination of speciation and gene duplication events, spanning more than one billion years of evolution. Notably, as these proteins evolved, the individual residues at each site in their amino acid sequences were replaced at markedly different rates. The relationship between protein structure, protein function, and site-specific rates of amino acid replacement is a topic of ongoing research. Additionally, there is much interest in the different evolutionary constraints imposed on sequences related by speciation (orthologs) versus sequences related by gene duplication (paralogs). A principal aim of this dissertation is to …