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Applied Statistics Commons

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Appalachian Student Research Forum

2018

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Full-Text Articles in Applied Statistics

A Comparison Of Unsupervised Methods For Dna Microarray Leukemia Data, Denise Harness Apr 2018

A Comparison Of Unsupervised Methods For Dna Microarray Leukemia Data, Denise Harness

Appalachian Student Research Forum

Advancements in DNA microarray data sequencing have created the need for sophisticated machine learning algorithms and feature selection methods. Probabilistic graphical models, in particular, have been used to identify whether microarrays or genes cluster together in groups of individuals having a similar diagnosis. These clusters of genes are informative, but can be misleading when every gene is used in the calculation. First feature reduction techniques are explored, however the size and nature of the data prevents traditional techniques from working efficiently. Our method is to use the partial correlations between the features to create a precision matrix and predict which …