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Examining Covid-19 Vaccine Hesitancy Among The Nevada African American Population Using The Social-Ecological Model, Katelyn Faulk Dec 2023

Examining Covid-19 Vaccine Hesitancy Among The Nevada African American Population Using The Social-Ecological Model, Katelyn Faulk

UNLV Theses, Dissertations, Professional Papers, and Capstones

In Nevada, COVID-19 vaccines have been widely available to the general population since March 2021; however, even with the wide availability of these vaccines only 40% of the African American population in Nevada has been fully vaccinated against COVID-19 as of May 2023. This is problematic as it has been shown that the African American population is disproportionately affected by COVID-19 with higher rates of cases, hospitalizations, and deaths when compared to other races or ethnicities. Through the literature, it has also been well documented that African Americans may experience hesitancy toward these vaccinations for a multitude of reasons including …


Development Of A Metapgs For Accurate Prediction Of Osteoporotic Fracture, Xiangxue Xiao Aug 2023

Development Of A Metapgs For Accurate Prediction Of Osteoporotic Fracture, Xiangxue Xiao

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Early identification of individuals at high-risk for osteoporotic fractures who may benefit from preventive intervention is essential. However, the predictive accuracy of the currently used fracture risk assessment tool remains suboptimal. The first aim of this research is to construct genome-wide polygenic scores for the femoral neck (PGS_FNBMDidpred) and total body BMD (PGS_TBBMDidpred) and to estimate their potential in identifying individuals with a high risk of osteoporotic fractures. The second aim is to validate the predictive performance of two previously established PGSs (PGS_FNBMDidpred and PGS_TBBMDidpred) in an external cohort …