Other Physics Commons^™

Verification And Evaluation Of A Passive Intensity Modulation Device For Bolus Conformal Therapy, Elizabeth Noel Hilliard

LSU Master's Theses

Purpose: Bolus electron conformal therapy (BECT) provides effective radiation treatment for superficial cancers and other diseases close to the skin surface, but can have as great as a 30% planning target volume (PTV) dose heterogeneity due to scattering from the irregular proximal bolus surface. Intensity modulated (IM) BECT can improve PTV dose homogeneity, but is not currently available. This study fabricated patient-specific passive intensity modulators and validated their delivering planned dose distributions calculated by a modified pencil beam redefinition algorithm (PBRA).

Methods: Two test-patterns and four patient-specific intensity modulators were designed, fabricated, and tested. Dose plans were generated …

Improved Target Coverage Of Spinal Metastases Through The Use Of Flattening Filter Free Beams, Laura Bennett

Dissertations & Theses (Open Access)

Of the patients that are diagnosed with metastatic disease, up to 40% will develop vertebral osseous metastases. These metastases tend to be located in close proximity to the spinal cord itself, making it difficult to achieve the recommended minimum dose of 14 Gy for single fraction SBRT or 21 Gy¹ for three fraction SBRT while maintaining acceptable doses to the cord and cauda equina. This proximity of the target to critical structures has the potential to compromise the efficacy of the radiation treatment plan in favor of reducing normal tissue dose, resulting in poor local control and tumor recurrence …