Open Access. Powered by Scholars. Published by Universities.®
Biological and Chemical Physics Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Publication
- File Type
Articles 1 - 7 of 7
Full-Text Articles in Biological and Chemical Physics
Seizure Prediction In Epilepsy Patients, Gary Dean Cravens
Seizure Prediction In Epilepsy Patients, Gary Dean Cravens
NSU REACH and IPE Day
Purpose/Objective: Characterize rigorously the preictal period in epilepsy patients to improve the development of seizure prediction techniques. Background/Rationale: 30% of epilepsy patients are not well-controlled on medications and would benefit immensely from reliable seizure prediction. Methods/Methodology: Computational model consisting of in-silico Hodgkin-Huxley neurons arranged in a small-world topology using the Watts-Strogatz algorithm is used to generate synthetic electrocorticographic (ECoG) signals. ECoG data from 18 epilepsy patients is used to validate the model. Unsupervised machine learning is used with both patient and synthetic data to identify potential electrophysiologic biomarkers of the preictal period. Results/Findings: The model has shown states corresponding to …
Therapeautic Cerium Oxide Nanoparticles, Angel E. Vasquez
Therapeautic Cerium Oxide Nanoparticles, Angel E. Vasquez
Symposium of Student Scholars
The overall goal of the research project is to create a glass that produces cerium oxide nanoparticles and as an efficient delivery mechanism. Cerium is able to exist as Ce3+ and Ce4+ because it has two partially filled subshells. This coexistence allows cerium oxide to have antioxidant properties that reduce the number of free radicals in that body that are associated with cancer, diabetes, and neurodegenerative diseases. In our laboratory, using a soluble borate glass, cerium oxide nanoparticles are created to coexist in Ce3+ and Ce4+ valences This borate glass composition is doped with different amounts of Cerium(IV) Oxide and …
Comparing Semi-Automated Segmentation Of Traditional-Resolution And High-Resolution Hyperpolarized 129xe Mri On Covid-19 Survivors, Tingting Wu
Undergraduate Student Research Internships Conference
Hyperpolarized gas MRI using inert gases like Xe is a valuable tool in visualizing lung ventilation in patients, and can be used as a longitudinal monitoring tool for patients with lung diseases. However, use of this method requires segmentation and quantification of parameters such as ventilation defect percentage (VDP), which is often very subjective depending on the observer. This study aimed to determine the accuracy and consistency of VDP calculation using the same MRI scans from COVID-19 patients, but with high resolution and low (traditional) resolution versions. Using a MATLAB script developed previously, it was found that in general, using …
Remotely Controlled Enzyme Behavior Using Localized Thermal Gradients, Sarah Brown
Remotely Controlled Enzyme Behavior Using Localized Thermal Gradients, Sarah Brown
UNO Student Research and Creative Activity Fair
No existing model describes an identified special case of enzyme behavior when directly stimulated with thermal energy via an RF field.
The ability to remotely influence cellular functions and outcomes is a new approach to targeted medicine. Nano-medicine and biotechnology are the future of medical diagnostics and treatment. The ability to remotely influence cellular functions and outcomes is a new approach to targeted medicine. Direct heating of an enzyme vs bulk heating changes the enzyme activity.
I tested how direct transfer of thermal energy changes rates of enzyme reactions. We created samples of enzymes, attached to ferrous (magnetic) nano-particles, and …
Emergence, Mechanics, And Development: How Behavior And Geometry Underlie Cowrie Seashell Form, Michael G. Levy, Michael R. Deweese
Emergence, Mechanics, And Development: How Behavior And Geometry Underlie Cowrie Seashell Form, Michael G. Levy, Michael R. Deweese
Biology and Medicine Through Mathematics Conference
No abstract provided.
Elucidating The Action Of A Regulatory Lipid Ligand Via Molecular Simulation: Cholesterol Swarms And The Inwardly Rectifying Potassium Channel, Belinda Akpa, Nicolas Barbera, Irena Levitan
Elucidating The Action Of A Regulatory Lipid Ligand Via Molecular Simulation: Cholesterol Swarms And The Inwardly Rectifying Potassium Channel, Belinda Akpa, Nicolas Barbera, Irena Levitan
Biology and Medicine Through Mathematics Conference
No abstract provided.
Optimization Of Cardiac Pacing Stimulation By Current Configuration –A Theoretical, Numerical And Experimental Study., Flavio H. Fenton, Hila Dvir, Neil Hardy
Optimization Of Cardiac Pacing Stimulation By Current Configuration –A Theoretical, Numerical And Experimental Study., Flavio H. Fenton, Hila Dvir, Neil Hardy
Biology and Medicine Through Mathematics Conference
No abstract provided.