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Full-Text Articles in Physics
Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost
Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost
All Dissertations
In confocal single-molecule FRET experiments, the joint distribution of FRET efficiency and donor lifetime distribution can reveal underlying molecular conformational dynamics via deviation from their theoretical Forster relationship. This shift is referred to as a dynamic shift. In this study, we investigate the influence of the free energy landscape in protein conformational dynamics on the dynamic shift by simulation of the associated continuum reaction coordinate Langevin dynamics, yielding a deeper understanding of the dynamic and structural information in the joint FRET efficiency and donor lifetime distribution. We develop novel Langevin models for the dye linker dynamics, including rotational dynamics, based …
The Effects Of Increasing Positively Charged Metal Ions Within Synovial Fluid, Kandisi Anyabwile
The Effects Of Increasing Positively Charged Metal Ions Within Synovial Fluid, Kandisi Anyabwile
Williams Honors College, Honors Research Projects
Osteoarthritis is a degenerative joint disease that affects 10% of men and 13% of women over age of 60. It is the degradation of the cartilage between two bones; obesity, age, overuse, or injury are major contributors to the development of this disease. The joint is incapsulated by the synovial sac filled with a viscous solution that aids in lubrication referred to as synovial fluid. If the synovial sac is ruptured due to injury, positive ions (K+, Na+, Ca2+, and Fe3+) may affect viscoelastic properties within the sac. The purpose of this …
Some Contributions Of Pure Math To Science, Herbert B.E. Case
Some Contributions Of Pure Math To Science, Herbert B.E. Case
Student and Lippitt Prize essays
An examination of the connection between math and science through discoveries in the subjects of astronomy, mechanics, physics and chemistry.