Physics Commons^™

Volumetric Imaging Using The Pupil-Matched Remote Focusing Technique In Light-Sheet Microscopy, Sayed Hassan Dibaji Foroushani

Optical Science and Engineering ETDs

ABSTRACT

The dissertation explores innovative techniques in light sheet microscopy, a pivotal tool in biomedical imaging, to enhance its speed, resolution, and efficiency in capturing dynamic biological processes. Light sheet microscopy allows for quick 3D imaging of biological specimens ranging from cells to organs with high spatiotemporal resolution, large field-of-view, and minimal damage, making it vital for in vivo imaging.

The first project introduces a novel optical concept designed to optimize Axially Swept Light Sheet Microscopy (ASLM). This technique is crucial for imaging specimens ranging from live cells to chemically cleared organs due to its versatility across different immersion media. …

Radio Insights Into Gamma-Ray Mysteries, Seth M. Bruzewski

Physics & Astronomy ETDs

In the time since its launch, the \textit{Fermi Gamma-Ray Space Telescope} has provided new and unparalleled views of the $\gamma$-ray sky, dramatically increasing our understanding of sources of high-energy radiation. During that same time, however, its ``unassociated'' sources have provided a consistent mystery: approximately one third of the modern gamma-ray sky remains completely unaccounted for in other electromagnetic regimes. While some of the fainter sources simply pose challenges in achieving the necessary signal-to-noise ratio, others are well constrained and have resisted traditional investigations for years, and in some cases, for over a decade. Radio astronomy has traditionally been the best …

Modeling Lithographic Quantum Dots And Donors For Quantum Computation And Simulation, Mitchell Ian Brickson

Physics & Astronomy ETDs

Our first focus is on few-hole quantum dots in germanium. We use discontinous Galerkin methods to discretize and solve the equations of a highly detailed k·p model that describes these systems, enabling a better understanding of experimental magnetospectroscopy results. We confirm the expected anisotropy of single-hole g-factors and describe mechanisms by which different orbital states have different g-factors. Building on this, we show that the g-factors in Ge holes are suciently sensitive to details of the device electrostatics that magnetospectroscopy data can be used to make a prediction of the underlying confinement potential. The second focus is on designing quantum …

Understanding The Nature Of Pulsars And Characterizing Propagation Effects Using Pulsar Timing, Pratik Kumar

Physics & Astronomy ETDs

Pulsars are highly magnetized stellar remnants, among the densest known objects, and primarily produce radio emission in the form of lighthouse beams sweeping across the line of sight as a regular train of pulses. Apart from providing tests for matter in high-density regimes, general relativity, and plasma emission; perhaps the most notable characteristic is their applicability as precise astronomical clocks to measure various effects. Pulsar Timing Arrays (PTAs) are galactic scale detectors analogous to ground-based detectors of Gravitational Waves (GWs) like LIGO, with the aim of detecting low-frequency nano-Hz GWs from coalescing binary supermassive black holes. PTAs consist of a …

Super-Resolution Microscopy With Color Centers In Diamond, Forrest A. Hubert

Optical Science and Engineering ETDs

This dissertation explores the development and application of diamond color centers, specifically the silicon-vacancy (SiV) and nitrogen-vacancy (NV) centers, in super-resolution microscopy and magnetic imaging techniques. It demonstrates the potential of SiV centers as photostable fluorophores in stimulated emission depletion (STED) microscopy, with a resolution of approximately 90 nm. The research also presents a method for nanoscale magnetic microscopy using NV centers by combining charge state depletion (CSD) microscopy with optically detected magnetic resonance (ODMR) to image magnetic fields produced by 30 nm iron-oxide nanoparticles. The individual magnetic feature width reaches ~100 nm while resolving magnetic field patterns from nanoparticles …

Near- And Far- Field Optical Response Of Ensembles Of Nanostructures, Lauren Zundel

Physics & Astronomy ETDs

The ability of metallic nanostructures to support collective oscillations of their conduction electrons, known as surface plasmons, makes them attractive candidates for a wide range of applications in areas as diverse as cancer therapy, biosensing, and solar energy harvesting. These applications are especially promising for periodic arrays of nanostructures, which can support collective modes known as lattice resonances, and for nanostructures with extreme aspect ratios that give rise to enhanced light-matter interaction. In this Thesis, we employ a coupled dipole model to theoretically explore the lattice resonances supported by complex arrays of nanoparticles containing multiple nanoparticles per unit cell. We …

Application Of Quantum Mechanical Techniques To Optical Waveguide Structures, Stuart Ward

Physics & Astronomy ETDs

The focus of this dissertation is on the application of supersymmetric quantum mechanics to the problem of microbending in optical waveguides and on the analysis of soliton decay due solely to quantum mechanical effects.

The techniques of supersymmetric quantum mechanics are applied to the equation of motion describing light propagation in an optical waveguide which is undergoing microbending. Based on these supersymmetric techniques, given a particular refractive index profile, one may derive a new refractive index profile which results in less loss due to the microbending -- the particular example of the monomial index profile is analyzed in detail. An …

High-Power Laser Cooling And Temperature-Dependent Fluorescence Studies Of Ytterbium Doped Silica, Brian Topper

Optical Science and Engineering ETDs

Experimental observation of optical refrigeration using ytterbium doped silica glass in recent years has created a new solution for heat mitigation in high-power laser systems, nonlinear fiber experiments, integrated photonics, and precision metrology. Current efforts of different groups focus on compositional optimization, fiber fabrication, and investigating how much silica can be cooled with a laser. At the start of this work, the best effort in laser cooling ytterbium doped silica saw cooling by 6 K from room temperature. This dissertation follows the experimental efforts that culminated in the increase of this initial record by one order of magnitude. Comprehensive spectroscopic …

Modified Geometries, Clifford Algebras And Graphs: Their Impact On Discreteness, Locality And Symmetr, Roma Sverdlov

Mathematics & Statistics ETDs

In this dissertation I will explore the question whether various entities commonly used in quantum field theory can be “constructed". In particular, can spacetime be “constructed" out of building blocks, and can Berezin integral be “constructed" in terms of Riemann integrals.

As far as “constructing" spacetime out of building blocks, it has been attempted by multiple scientific communities and various models were proposed. But the common downfall is they break the principles of relativity. I will explore the ways of doing so in such a way that principles of relativity are respected. One of my approaches is to replace points …

Filaments And Their Application To Air Lasing, Spectroscopy, And Guided Discharge, Ali Rastegari

Optical Science and Engineering ETDs

Laser filamentation is a fascinating phenomenon that occurs when an intense laser beam travels through transparent materials, in particular air. At sufficiently high power (TW in the near IR, GW in the UV), instead of spreading out like a regular laser beam, something remarkable happens: the laser beam becomes tightly focused, creating a thin and intense column of light called a laser filament. Laser filamentation is characterized by two main properties: (I) a high-intensity core that remains narrow over long distances beyond the Rayleigh range and (II) a low-density plasma channel within the core. In recent years, laser filamentation has …

Rigorous Analysis Of Markov Processes With Applications To Quantum Information, Samuel Edwin Slezak

Physics & Astronomy ETDs

We present a rigorous analysis of the rapid convergence of techniques based on Markov chains for the simulation of thermal quantum systems. We show that a classical computing algorithm called path integral Monte Carlo is capable of simulating thermal states of transverse field Ising models above a threshold temperature by demonstrating the existence of a rapidly mixing Markov chain. We then turn to quantum computing algorithms and show that an idealized version of quantum Metropolis sampling can efficiently simulate systems that satisfy the eigenstate thermalization hypothesis. In a related result, we find a class of stoquastic frustration free Hamiltonians that …

The Quantum Computational Utility Of Symmetry-Protected Topological Order: From Near-Term Advantages To Universal Measurement-Based Quantum Computing, Austin Kevin Daniel

Physics & Astronomy ETDs

Quantum computers offer new avenues to approach difficult problems by taking advantage of the strange and often nonintuitive phenomena present in quantum physics. Though many quantum algorithms are believed or known to outperform the best known classical algorithms, the fundamental mechanism granting them their power remains elusive. In measurement-based quantum computation (MBQC), two key resources have been show to enable universal and provably nonclassical quantum computations, respectively. These are symmetry-protected topological order (SPTO), a notion describing a class of quantum magnets with hidden long-range correlations in their entanglement structure, and quantum contextuality, the fact that a quantum measurement outcome inherently …

Femtotesla Magnetometry And Nanoscale Imaging With Color Centers In Diamond, Yaser Silani

Optical Science and Engineering ETDs

Intriguing photophysical properties of color centers in diamond make them ideal candidates for many applications from imaging and sensing to quantum networking. In the first part of this work, we have studied the silicon vacancy (SiV) centers in diamond for nanoscale imaging applications. We showed that these centers are promising fluorophores for Stimulated Emission Depletion (STED) microscopy, owing to their photostable, near-infrared emission and favorable photophysical properties. In the second part, we built a femtotesla Radio-Frequency (RF) magnetometer based on the diamond nitrogen vacancy (NV) centers and magnetic flux concentrators. We used this sensor to remotely detect Nuclear Quadrupole Resonance …

Investigation Of Gaas Double Heterostructures For Photonic Heat Engines, Nathan Giannini-Hutchin

Optical Science and Engineering ETDs

The creation of a laser cooled semiconductor device has been a long sought achievement. GaAs-based devices have emerged as a promising candidate for the realization of this goal. Efforts to improve the efficiency of such devices have enabled the material to exhibit external quantum efficiencies (EQE, a measure of the probability that an excitation leads to the emission of a photon) of 99.5\%. Despite this impressive feat, a laser coolable device remains elusive.

To investigate the obstacles to such a device, the material characteristics of GaAs-based double heterostructures (DHS) are theoretically and experimentally examined. Through this study, a GaAs $\vert$ …

Investigation Of Laser And Nonlinear Properties Of Anderson Localizing Optical Fibers, Cody Ryan Bassett

Optical Science and Engineering ETDs

In this dissertation, I investigate the possibility of lasing and nonlinear phenomena in completely solid-state transverse Anderson localizing optical fibers (TALOFs). I examine three areas within this range of topics. The research in nonlinear phenomena focuses on four-wave mixing (FWM). FWM is of high interest in TALOFs due to the fact that guided localized modes of the fiber each have different propagation constants, and thus unique possible FWM pairs can be generated from the same input pump beam. I demonstrate the generation of FWM in the TALOF by pumping it with 532 nm light into a localized mode and observing …

Distance Estimates To Evolved Stars Using Infrared Emission And Verification And Validation Of The Plasma Code Empire, Brandon M. Medina

Physics & Astronomy ETDs

Gaining insight into the structure and dynamics of the Milky Way is important for understanding the universe on a large scale. Evolved stars on the Asymptotic Giant Branch are useful for studying the Milky Way because their emission is peaked in the infrared, where interstellar extinction effects are not as dominant. To further understand the physical properties of these objects like luminosity and investigate the Galaxy's structure, we need distance estimates. Obtaining distance estimates for these evolved stars via trigonometric parallax measurements is time-consuming, so infrared surveys studying Asymptotic Giant Branch stars can benefit from other distance estimate methods. In …

Ultrashort Pulse Laser Filamentation Electrical And Optical Diagnostic Comparison, James E. Wymer

Optical Science and Engineering ETDs

Results presented here examine the effect of changing gas pressure on the radio frequency (RF) emissions of an ultrashort pulse laser filament plasma and how those emissions vary longitudinally in the laser focal region. We use a WR284 rectangular waveguide with a 1.5 cm hole that allows the beam through. A 3.2 GHz microwave signal is emitted in the waveguide, and signals are received through a waveguide-to-coax antenna connected to an HP8470B Schottky diode. By enabling and disabling the 3.2 GHz signal, we measure both the self-emitted RF from a USPL filament and subsequently the degree of attenuation a filament …

Atomic Gradiometry Based On The Interference Of Microwave Optical Sidebands, Kaleb L. Campbell

Optical Science and Engineering ETDs

We describe a novel pulsed magnetic gradiometer based on the optical interference of sidebands generated using two spatially separated alkali vapor cells. The sidebands are produced with high efficiency using parametric frequency conversion of a probe beam interacting with Rubiduim 87 atoms in a coherent superposition of magnetically sensitive hyperfine ground states. First, experimental evidence of the sideband process is described for both steady-state and pulsed operation. Then, a theoretical framework is developed that accurately models sideband generation based on density matrix formalism. The gradiometer is then constructed using two spatially separated vapor cells, and a beat-note is generated. The …

Fiesta And Shock-Driven Flows, Brian E. Romero

Mechanical Engineering ETDs

In this study, the interaction of a shock with various gas and particle interfaces is analyzed through simulations using a new, GPU capable, multi-species flow solver, FIESTA (Fast, Interface Evolution, Shocks, and Transport in the Atmosphere), de- veloped for this research. The cases studied include the interaction between a shock and i) a two-dimensional (2D), circular cloud of a dense gas; ii) a 2D curtain of a dense gas; iii) a three-dimensional (3D) cylinder of a dense gas, and iv) a 3D curtain of solid particles.

In simulations of a 2D gas curtain and a 3D gas column, the curtain …

Resource Estimation For Quantum Simulation Algorithms, Changhao Yi

Physics & Astronomy ETDs

A major application of quantum computers is simulating other quantum systems that are intractable to simulate classically. The broad family of algorithms for this problem go by the name of quantum simulation. Product formulas provide resource efficient and practical methods to simulate Hamiltonian dynamics. In this thesis, we study the resource estimation of quantum simulation by product formula from two aspects. First, we provide a detailed analysis of the algorithm itself. Using the effective Hamiltonian perspective, we successfully reduce the circuit complexity of quantum phase estimation and digital adiabatic simulation. Second, we analyze the performance of dynamical decoupling, a widely-used …

Applications Of Machine Learning Algorithms In Materials Science And Bioinformatics, Mohammed Quazi

Mathematics & Statistics ETDs

The piezoelectric response has been a measure of interest in density functional theory (DFT) for micro-electromechanical systems (MEMS) since the inception of MEMS technology. Piezoelectric-based MEMS devices find wide applications in automobiles, mobile phones, healthcare devices, and silicon chips for computers, to name a few. Piezoelectric properties of doped aluminum nitride (AlN) have been under investigation in materials science for piezoelectric thin films because of its wide range of device applicability. In this research using rigorous DFT calculations, high throughput ab-initio simulations for 23 AlN alloys are generated.

This research is the first to report strong enhancements of piezoelectric properties …

An Interdisciplinary Approach To Understanding Volcanoes And Their Processes, Katherine Cosburn

Physics & Astronomy ETDs

To better understand volcanoes and their processes is important from both a fundamental science perspective and for hazard monitoring purposes. The complexity and limitations we face in pursuing such a science are numerous and this dissertation explores how an interdisciplinary approach combining physics, computer science, and volcanology can address this complexity in a straightforward and meaningful way. This is achieved through various modelling techniques across three studies: (1) a first-order analytic modelling of stratovolcano topographic shape, (2) the use of a Bayesian joint inversion on gravity and novel cosmic-ray muon measurements for imaging flat-lying subsurface density anomalies, and (3) the …

Nonequilibrium And Nonlinear Dynamics In Collective Spin Models And Implementations Using Quantum Feedback Control, Manuel H. Munoz Arias

Physics & Astronomy ETDs

Out-of-equilibrium dynamics generalizes the study of ground states of quantum Hamiltonians at zero temperature, to that of dynamical quasi-steady states of quantum systems far from equilibrium. In this dissertation I discuss dynamical quantum phase transitions and out-of-equilibrium phases of matter in models of collective spins with multi-body interactions. These models, based on collective degrees of freedom, allow an exact description of the thermodynamic limit via the mean-field description. In this limit, the nonequilibrium dynamics of properties of quantum states is mapped to the nonlinear dynamics of classical variables, and thus it can be analyzed using tools from the theory of …

Examination Of Ionization In Cesium Diode Pumped Alkali Lasers With An Ion Chamber Diagnostic, Benjamin Oliker

Optical Science and Engineering ETDs

Diode pumped alkali lasers (DPALs) are leading candidates for future high power applications, with many potential utilities for the military, aerospace, communications, and scientific diagnostics. A critical step in their development is measurement and understanding of unwanted ionization processes that occur inside the laser, which decrease efficiency, reduce the usable alkali population, and increase heat load. In this dissertation, direct measurement of the ionization rate of a cesium DPAL gain medium are made for the first time, via application of an ion chamber diagnostic. Results will demonstrate that the rate of ionization is slow compared to pump absorption, with a …

Design And Characterization Of Frequency Tripling Mirrors, Amir Khabbazi Oskouei

Optical Science and Engineering ETDs

Aperiodic stacks of dielectric low- and high-index films can be designed to enhance third-harmonic generation (THG) in reflection of near infrared laser pulses using computer optimization. Numerical and analytical results suggest that the TH energy increases rapidly with increasing number of films and the ratio of the high and low index.

Our optical matrix based THG model that takes into account the full pulse bandwidth predicts conversion efficiencies of about 7% for transform-limited Gaussian pulse bandwidths of 16 nm for mirrors with 45 layers, which exceed those expected from periodic designs. Stability against film thickness fluctuations expected from the deposition …

Nano-Fabricated Atomic Waveguides For Inertial Measurements, Adrian S. Orozco

Physics & Astronomy ETDs

Atom-based inertial measurement systems can measure acceleration and rotation very precisely in the laboratory. The central element of these systems is atom interferometry where the phase shifts are sensitive to inertial forces experienced by the atom. This phenomenon has been used to make atom-based gravimeters, gradiometers, and gyroscopes. Recent effort has been made to make these systems more compact which require small size, light weight, and low power (SWaP). Nano-fabricated waveguides, such as photonic waveguides or optical nanofibers, offer a promising avenue to meet these goals. They have dimensions comparable to the guided light’s wavelength producing a mode that not …

Reliability Of Quantum Simulation On Nisq-Era Devices, Karthik R. Chinni

Physics & Astronomy ETDs

We study the reliability of quantum simulation on Noisy intermediate-scale quantum (NISQ)-era devices in the presence of errors and imperfections, with a focus on exploring the relationship between the properties of the system being simulated and the errors in the output of the simulator. We first consider simulation of the Lipkin-Meshkov-Glick (LMG) model, which becomes chaotic in the presence of a background time-dependent perturbation. Here we show that the quantities that depend on the global structure of the phase space are robust, while other quantities that depend on the local trajectories are fragile and cannot be reliably extracted from the …

Magnetic Microscopy And Search For Exotic Interaction Detection With Color Centers In Diamond, Nathaniel Ristoff

Physics & Astronomy ETDs

Nitrogen vacancy (NV) centers have been used extensively for the measurement of magnetic fields in applications of geology, biology, medicine, and fundamental physics. In regard to fundamental physics, NV centers offer a unique opportunity to test potential velocity dependant spin-spin interactions as well as velocity-spin interactions at the micron scale. In regards to magnetic materials, NV centers offer a platform to investigate magnetic properties of nanoparticles in an individual, but highly parallelized measurement. In this work, an experiment is proposed to measure a potential fundamental interaction between spins, mediated by an integer spin boson. These velocity dependent interactions will couple …

Intracavity Phase Interferometry Based Fiber Sensors, Luke Jameson Horstman

Optical Science and Engineering ETDs

Intracavity Phase Interferometry (IPI) is a detection technique that exploits the inherent sensitivity of a laser's frequency to the parameters of its cavity. Intracavity interferometry is orders of magnitude more sensitive than its extracavity alternatives. This dissertation improves on previous free-space proof-of-concept designs. By implementing the technique in fiber optics, using optical parametric oscillation, and investigating non-Hermitian quantum mechanics and dispersion tailoring enhancement techniques, IPI has become more applicable and sensitive. Ring and linear IPI configurations were realized in this work, both operating as bidirectional fiber optical parametric oscillators. The benefit of using externally pumped synchronous optical parametric oscillation is …

Ultrafast Spectroscopy Of Air Lasing In Filaments, Brian Robert Kamer

Optical Science and Engineering ETDs

Filamentation in air is a phenomenon that has been extensively investigated for the last two decades. At sufficiently high intensity, even air is a nonlinear medium. These intensities are reached with ultrashort pulses (50 to 100 fs) of more than 1 J energy, which self-focus in air, reach ionizing intensities of oxygen and nitrogen, creating a plasma that defocuses the beam. The air filament is a self-induced waveguide resulting from a balance of focusing and defocusing. In this work new techniques were developed to visualize and analyze this phenomenon through its emission, in particu- lar the UV emission of the …