Physics Commons^™

Six Types Of Multistability In A Neuronal Model Based On Slow Calcium Current, Tatiana Malashchenko, Andrey Shilnikov, Gennady Cymbalyuk

Neuroscience Institute Faculty Publications

Background: Multistability of oscillatory and silent regimes is a ubiquitous phenomenon exhibited by excitable systems such as neurons and cardiac cells. Multistability can play functional roles in short-term memory and maintaining posture. It seems to pose an evolutionary advantage for neurons which are part of multifunctional Central Pattern Generators to possess multistability. The mechanisms supporting multistability of bursting regimes are not well understood or classified.

Methodology/Principal Findings: Our study is focused on determining the bio-physical mechanisms underlying different types of co-existence of the oscillatory and silent regimes observed in a neuronal model. We develop a low-dimensional model typifying the dynamics …