Physics Commons^™

Matlab Codes To Compute Granger Causality And Other Spectral Measures, Mukesh Dhamala

Physics and Astronomy Faculty Publications

Matlab codes to compute Granger causality and other spectral measures

Information Literacy & Open Access For Physics And Astronomy Graduate Students, Jackie K. Werner

University Library Faculty Presentations

This presentation covers research on the physics and astronomy graduate students’ use and understanding of open access resources. The research, which was conducted in summer 2015, surveyed the physics and astronomy graduate students of Georgia Institute of Technology to discover how graduate students discover open access and other academic resources, as well as their level of awareness about open access in general and specific OA databases in particular. The research also included an interview with the graduate studies advisor in the Physics & Astronomy department Georgia Tech. The presentation also describes open access resources in Physics and Astronomy and relates …

Atomic-Scale Diffractive Imaging Of Sub-Cycle Electron Dynamics In Condensed Matter, Vladislav S. Yakovlev, Mark I. Stockman, Ferenc Krausz, Peter Baum

Physics and Astronomy Faculty Publications

For interaction of light with condensed-matter systems, we show with simulations that ultrafast electron and X-ray diffraction can provide a time-dependent record of charge-density maps with sub-cycle and atomic-scale resolutions. Using graphene as an example material, we predict that diffraction can reveal localised atomic-scale origins of optical and electronic phenomena. In particular, we point out nontrivial relations between microscopic electric current and density in undoped graphene.

Control Of Plasmonic Nanoantennas By Reversible Metal-Insulator Transition, Yohannes Abate, Robert E. Marvel, Jed I. Ziegler, Sampath Gamage, Mohammad H. Javani, Mark I. Stockman, Richard F. Haglund

Physics and Astronomy Faculty Publications

We demonstrate dynamic reversible switching of VO2 insulator-to-metal transition (IMT) locally on the scale of 15 nm or less and control of nanoantennas, observed for the first time in the near-field. Using polarization-selective near-field imaging techniques, we simultaneously monitor the IMT in VO2 and the change of plasmons on gold infrared nanoantennas. Structured nanodomains of the metallic VO2 locally and reversibly transform infrared plasmonic dipole nanoantennas to monopole nanoantennas. Fundamentally, the IMT in VO2 can be triggered on femtosecond timescale to allow ultrafast nanoscale control of optical phenomena. These unique features open up promising novel applications in active nanophotonics.

Brain Effective Connectivity During Motor-Imagery And Execution Following Stroke And Rehabilitation, Sahil Bajaj, Andrew Butler, Daniel Drake, Mukesh Dhamala

Physics and Astronomy Faculty Publications

Brain areas within the motor system interact directly or indirectly during motor-imagery and motor-execution tasks. These interactions and their functionality can change following stroke and recovery. How brain network interactions reorganize and recover their functionality during recovery and treatment following stroke are not well understood. To contribute to answering these questions, we recorded blood oxygenation-level dependent (BOLD) functional magnetic resonance imaging (fMRI) signals from10 stroke survivors and evaluated dynamical causal modeling (DCM)-based effective connectivity among three motor areas: primary motor cortex (M1), premotor cortex (PMC) and supplementary motor area (SMA), during motor-imagery and motor-execution tasks. We compared the connectivity between …

Functional Organization And Restoration Of The Brain Motor-Execution Network After Stroke And Rehabilitation, Sahil Bajaj, Andrew Butler, Daniel Drake, Mukesh Dhamala

Physics and Astronomy Faculty Publications

Multiple cortical areas of the human brain motor system interact coherently in the low frequency range (<0.1 Hz), even in the absence of explicit tasks. Following stroke, cortical interactions are functionally disturbed. How these interactions are affected and how the functional organization is regained from rehabilitative treatments as people begin to recover motor behaviors has not been systematically studied. We recorded the intrinsic functional magnetic resonance imaging (fMRI) signals from 30 participants: 17 young healthy controls and 13 aged stroke survivors. Stroke participants underwent mental practice (MP) or both mental practice and physical therapy (MP+PT) within 14–51 days following stroke. We investigated the network activity of five core areas in the motor-execution network, consisting of the left primary motor area (LM1), the right primary motor area (RM1), the left pre-motor cortex (LPMC), the right pre-motor cortex (RPMC) and the supplementary motor area (SMA). We discovered that (i) the network activity dominated in the frequency range 0.06–0.08 Hz for all the regions, and for both able-bodied and stroke participants (ii) the causal information flow between the regions: LM1 and SMA, RPMC and SMA, RPMC and LM1, SMA and RM1, SMA and LPMC, was reduced significantly for stroke survivors (iii) the flow did not increase significantly after MP alone and (iv) the flow among the regions during MP+PT increased significantly. We also found that sensation and motor scores were significantly higher and correlated with directed functional connectivity measures when the stroke-survivors underwent MP+PT but not MP alone. The findings provide evidence that a combination of mental practice and physical therapy can be an effective means of treatment for stroke survivors to recover or regain the strength of motor behaviors, and that the spectra of causal information flow can be used as a reliable biomarker for evaluating rehabilitation in stroke survivors.

Vibrational Spectroscopy Of Photosystem I, Gary Hastings

Physics and Astronomy Faculty Publications

Fourier transform infrared difference spectroscopy (FTIR DS) has beenwidely used to study the structural details of electron transfer cofactors (and their binding sites) in many types of photosynthetic protein complexes. This review focuses in particular onwork that has been done to investigate the A1 cofactor in photosystemI photosynthetic reaction centers. A reviewof this subject area last appeared in 2006 [1], so onlywork undertaken since then will be covered here. Following light excitation of intact photosystem I particles the P700+A1 \ secondary radical pair state is formed within 100 ps. This state decays within 300 ns at room temperature, or 300 …

Oscillatory Motor Network Activity During Rest And Movement: An Fnirs Study, Sahil Bajaj, Daniel Drake, Andrew Butler, Mukesh Dhamala

Physics and Astronomy Faculty Publications

Coherent network oscillations (<0.1 Hz) linking distributed brain regions are commonly observed in the brain during both rest and task conditions. What oscillatory network exists and how network oscillations change in connectivity strength, frequency and direction when going from rest to explicit task are topics of recent inquiry. Here, we study network oscillations within the sensorimotor regions of able-bodied individuals using hemodynamic activity as measured by functional near-infrared spectroscopy (fNIRS). Using spectral interdependency methods, we examined how the supplementary motor area (SMA), the left premotor cortex (LPMC) and the left primary motor cortex (LM1) are bound as a network during extended resting state (RS) and between-tasks resting state (btRS), and how the activity of the network changes as participants execute left, right, and bilateral hand (LH, RH, and BH) finger movements. We found: (i) power, coherence and Granger causality (GC) spectra had significant peaks within the frequency band (0.01–0.04 Hz) during RS whereas the peaks shifted to a bit higher frequency range (0.04–0.08 Hz) during btRS and finger movement tasks, (ii) there was significant bidirectional connectivity between all the nodes during RS and unidirectional connectivity from the LM1 to SMA and LM1 to LPMC during btRS, and (iii) the connections from SMA to LM1 and from LPMC to LM1 were significantly modulated in LH, RH, and BH finger movements relative to btRS. The unidirectional connectivity from SMA to LM1 just before the actual task changed to the bidirectional connectivity during LH and BH finger movement. The uni-directionality could be associated with movement suppression and the bi-directionality with preparation, sensorimotor update and controlled execution. These results underscore that fNIRS is an effective tool for monitoring spectral signatures of brain activity, which may serve as an important precursor before monitoring the recovery progress following brain injury.

Magneto-Transport Characteristics Of A 2d Electron System Driven To Negative Magneto-Conductivity By Microwave Photoexcitation, Ramesh G. Mani, Annika Kriisa

Physics and Astronomy Faculty Publications

Negative diagonal magneto-conductivity/resistivity is a spectacular- and thought provoking-property of driven, far-from-equilibrium, low dimensional electronic systems. The physical response of this exotic electronic state is not yet fully understood since it is rarely encountered in experiment. The microwave-radiation-induced zero-resistance state in the high mobility GaAs/AlGaAs 2D electron system is believed to be an example where negative magneto-conductivity/resistivity is responsible for the observed phenomena. Here, we examine the magneto-transport characteristics of this negative conductivity/ resistivity state in the microwave photo-excited two-dimensional electron system (2DES) through a numerical solution of the associated boundary value problem. The results suggest, surprisingly, that a bare …

Is The Brain’S Inertia For Motor Movements Different For Acceleration And Deceleration?, Bhim M. Adhikari, Kristen M. Quinn, Mukesh Dhamala

Physics and Astronomy Faculty Publications

The brain’s ability to synchronize movements with external cues is used daily, yet neuroscience is far from a full understanding of the brain mechanisms that facilitate and set behavioral limits on these sequential performances. This functional magnetic resonance imaging (fMRI) study was designed to help understand the neural basis of behavioral performance differences on a synchronizing movement task during increasing (acceleration) and decreasing (deceleration) metronome rates. In the MRI scanner, subjects were instructed to tap their right index finger on a response box in synchrony to visual cues presented on a display screen. The tapping rate varied either continuously or …

Size-Dependent Giant-Magnetoresistance In Millimeter Scale Gaas/Algaas 2d Electron Devices, Ramesh G. Mani, Annika Kriisa, Werner Wegscheider

Physics and Astronomy Faculty Publications

Large changes in the electrical resistance induced by the application of a small magnetic field are potentially useful for device-applications. Such Giant Magneto-Resistance (GMR) effects also provide new insights into the physical phenomena involved in the associated electronic transport. This study examines a ‘‘bell-shape’’ negative GMR that grows inmagnitude with decreasing temperatures inmm-wide devices fabricated from the high-mobility GaAs/AlGaAs 2-Dimensional Electron System (2DES). Experiments show that the span of this magnetoresistance on the magnetic-field-axis increases with decreasing device width, W, while there is no concurrent Hall resistance, Rxy, correction. A multi-conduction model, including negative diagonalconductivity, and non-vanishing off-diagonal conductivity, reproduces …

Comparison Of Calculated And Experimental Isotope Edited Ftir Difference Spectra For Purple Bacterial Photosynthetic Reaction Centers With Different Quinones Incorporated Into The Qa Binding Site, Nan Zhao, Hari Prasad Lamichhane, Gary Hastings

Physics and Astronomy Faculty Publications

Previously we have shown that ONIOM type (QM/MM) calculations can be used to simulate isotope edited FTIR difference spectra for neutral ubiquinone in the QA binding site in Rhodobacter sphaeroides photosynthetic reaction centers. Here we considerably extend upon this previous work by calculating isotope edited FTIR difference spectra for reaction centers with a variety of unlabeled and 18 O labeled foreign quinones incorporated into the QA binding site. Isotope edited spectra were calculated for reaction centers with 2,3-dimethoxy-5,6-dimethyl-1,4-benzoquinone (MQ0 ), 2,3,5,6-tetramethyl-1, 4-benzoquinone (duroquinone, DQ), and 2,3-dimethyl-l,4-naphthoquinone (DMNQ) incorporated, and compared to corresponding experimental spectra. The calculated and experimental spectra agree …

Higher Frequency Network Activity Flow Predicts Lower Frequency Node Activity In Intrinsic Low-Frequency Bold Fluctuations, Sahil Bajaj, Bhim M. Adhikari, Mukesh Dhamala

Physics and Astronomy Faculty Publications

The brain remains electrically and metabolically active during resting conditions. The low-frequency oscillations (LFO) of the blood oxygen level-dependent (BOLD) signal of functional magnetic resonance imaging (fMRI) coherent across distributed brain regions are known to exhibit features of this activity. However, these intrinsic oscillations may undergo dynamic changes in time scales of seconds to minutes during resting conditions. Here, using wavelet-transform based timefrequency analysis techniques, we investigated the dynamic nature of default-mode networks from intrinsic BOLD signals recorded from participants maintaining visual fixation during resting conditions. We focused on the default-mode network consisting of the posterior cingulate cortex (PCC), the …

Calculated Vibrational Properties Of Ubisemiquinones, Hari P. Lamichhane, Gary Hastings

Physics and Astronomy Faculty Publications

Density functional theory has been used to calculate harmonic normal mode vibrational frequencies for unlabeled and isotopelabeled ubisemiquinones in both the gas phase and in several solvents. It is shown that four methoxy group conformations are likely to be present in solution at room temperature. Boltzmann weighted infrared and Raman spectra for the four conformers were calculated, and composite spectra that are the sum of the Boltzmann weighted spectra were produced. These composite spectra were compared to experimental FTIR and resonance Raman spectra, and it is shown that the calculated band frequencies, relative band intensities, and ¹³C and ^{18 …}

Observation Of Resistively Detected Hole Spin Resonance And Zero-Field Pseudo-Spin Splitting In Epitaxial Graphene, Ramesh G. Mani, John Hankinson, Claire Berger, Walter A. De Heer

Physics and Astronomy Faculty Publications

Electronic carriers in graphene show a high carrier mobility at room temperature. Thus, this system is widely viewed as a potential future charge-based high-speed electronic material to complement–or replace–silicon. At the same time, the spin properties of graphene have suggested improved capability for spin-based electronics or spintronics and spin-based quantum computing. As a result, the detection, characterization and transport of spin have become topics of interest in graphene. Here we report a microwave photo-excited transport study of monolayer and trilayer graphene that reveals an unexpectedly strong microwave-induced electrical response and dual microwave-induced resonances in the dc resistance. The results suggest …

Six Types Of Multistability In A Neuronal Model Based On Slow Calcium Current, Tatiana Malashchenko, Andrey Shilnikov, Gennady Cymbalyuk

Neuroscience Institute Faculty Publications

Background: Multistability of oscillatory and silent regimes is a ubiquitous phenomenon exhibited by excitable systems such as neurons and cardiac cells. Multistability can play functional roles in short-term memory and maintaining posture. It seems to pose an evolutionary advantage for neurons which are part of multifunctional Central Pattern Generators to possess multistability. The mechanisms supporting multistability of bursting regimes are not well understood or classified.

Methodology/Principal Findings: Our study is focused on determining the bio-physical mechanisms underlying different types of co-existence of the oscillatory and silent regimes observed in a neuronal model. We develop a low-dimensional model typifying the dynamics …