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Articles 1 - 10 of 10
Full-Text Articles in Physics
Sars-Cov-2 Spike Conformation Determines Plasma Neutralizing Activity Elicited By A Wide Panel Of Human Vaccines, John E. Bowen, Young-Jun Park, Cameron Stewart, Jack T. Brown, William K. Sharkey, Alexandra C. Walls, Anshu Joshi, Kumail Ahmed, Asefa Shariq, Najeeha Talat Iqbal
Sars-Cov-2 Spike Conformation Determines Plasma Neutralizing Activity Elicited By A Wide Panel Of Human Vaccines, John E. Bowen, Young-Jun Park, Cameron Stewart, Jack T. Brown, William K. Sharkey, Alexandra C. Walls, Anshu Joshi, Kumail Ahmed, Asefa Shariq, Najeeha Talat Iqbal
Department of Paediatrics and Child Health
Numerous safe and effective coronavirus disease 2019 vaccines have been developed worldwide that use various delivery technologies and engineering strategies. We show here that vaccines containing prefusion-stabilizing S mutations elicit antibody responses in humans with enhanced recognition of S and the S1 subunit relative to postfusion S as compared with vaccines lacking these mutations or natural infection. Prefusion S and S1 antibody binding titers positively and equivalently correlated with neutralizing activity, and depletion of S1-directed antibodies completely abrogated plasma neutralizing activity. We show that neutralizing activity is almost entirely directed to the S1 subunit and that variant cross-neutralization is mediated …
Arrayed Waveguide Lens For Beam Steering, Mostafa Honari-Latifpour, Ali Binaie, Mohammad Amin Eftekhar, Nicholas Madamopoulos, Mohammad-Ali Miri
Arrayed Waveguide Lens For Beam Steering, Mostafa Honari-Latifpour, Ali Binaie, Mohammad Amin Eftekhar, Nicholas Madamopoulos, Mohammad-Ali Miri
Publications and Research
Integrated planar lenses are critical components for analog optical information processing that enable a wide range of applications including beam steering. Conventional planar lenses require gradient index control which makes their on-chip realization challenging. Here, we introduce a new approach for beam steering by designing an array of coupled waveguides with segmented tails that allow for simultaneously achieving planar lensing and off-chip radiation. The proposed arrayed waveguide lens is built on engineering the evanescent coupling between adjacent channels to realize a photonic lattice with an equi-distant ladder of propagation constants that emulates the continuous parabolic index profile. Through coupled-mode analysis …
A Progress Report On Numerical Methods For Bgk-Type Kinetic Equations, Evan Habbershaw, Steven M. Wise
A Progress Report On Numerical Methods For Bgk-Type Kinetic Equations, Evan Habbershaw, Steven M. Wise
Faculty Publications and Other Works -- Mathematics
In this report we review some preliminary work on the numerical solution of BGK-type kinetic equations of particle transport. Such equations model the motion of fluid particles via a density field when the kinetic theory of rarefied gases must be used in place of the continuum limit Navier-Stokes and Euler equations. The BGK-type equations describe the fluid in terms of phase space variables, and, in three space dimensions, require 6 independent phase-space variables (3 for space and 3 for velocity) for accurate simulation. This requires sophisticated numerical algorithms and efficient code to realize predictions over desired space and time scales. …
Particle-In-Cell Simulations Of Ion Dynamics In A Pinched-Beam Diode, Jesse C. Foster, John W. Mcclory, S. B. B. Swanekamp, D. D. Hinshelwood, A. S. Richardson, Paul E. Adamson, J. W. Schumer, R. W. James, P. F. Ottinger, D. Mosher
Particle-In-Cell Simulations Of Ion Dynamics In A Pinched-Beam Diode, Jesse C. Foster, John W. Mcclory, S. B. B. Swanekamp, D. D. Hinshelwood, A. S. Richardson, Paul E. Adamson, J. W. Schumer, R. W. James, P. F. Ottinger, D. Mosher
Faculty Publications
article-in-cell simulations of a 1.6 MV, 800 kA, and 50 ns pinched-beam diode have been completed with emphasis placed on the quality of the ion beams produced. Simulations show the formation of multiple regions in the electron beam flow characterized by locally high charge and current density (“hot spots”). As ions flow through the electron-space-charge cloud, these hot spots electrostatically attract ions to produce a non-uniform ion current distribution. The length of the cavity extending beyond the anode-to-cathode gap (i.e., behind the cathode tip) influences both the number and amplitude of hot spots. A longer cavity length increases the number …
Foundations Of Plasmas For Medical Applications, T. Von Woedtke, Mounir Laroussi, M. Gherardi
Foundations Of Plasmas For Medical Applications, T. Von Woedtke, Mounir Laroussi, M. Gherardi
Electrical & Computer Engineering Faculty Publications
Plasma medicine refers to the application of nonequilibrium plasmas at approximately body temperature, for therapeutic purposes. Nonequilibrium plasmas are weakly ionized gases which contain charged and neutral species and electric fields, and emit radiation, particularly in the visible and ultraviolet range. Medically-relevant cold atmospheric pressure plasma (CAP) sources and devices are usually dielectric barrier discharges and nonequilibrium atmospheric pressure plasma jets. Plasma diagnostic methods and modelling approaches are used to characterize the densities and fluxes of active plasma species and their interaction with surrounding matter. In addition to the direct application of plasma onto living tissue, the treatment of liquids …
Beamline For E-Beam Processing At Uitf, G. Ciovati, C. Bott, S. Gregory, F. Hannon, Xi Li, M. Mccaughan, R. Pearce, M. Poelker, H. Vennekate
Beamline For E-Beam Processing At Uitf, G. Ciovati, C. Bott, S. Gregory, F. Hannon, Xi Li, M. Mccaughan, R. Pearce, M. Poelker, H. Vennekate
Electrical & Computer Engineering Faculty Publications
No abstract provided.
Grand Challenges In Low Temperature Plasmas, Xinpei Lu, Peter J. Bruggeman, Stephan Reuter, George Naidis, Annemie Bogaerts, Mounir Laroussi, Michael Keidar, Eric Robert, Jean-Michel Pouvesle, Dawei Liu, Kostya (Ken) Ostrikov
Grand Challenges In Low Temperature Plasmas, Xinpei Lu, Peter J. Bruggeman, Stephan Reuter, George Naidis, Annemie Bogaerts, Mounir Laroussi, Michael Keidar, Eric Robert, Jean-Michel Pouvesle, Dawei Liu, Kostya (Ken) Ostrikov
Electrical & Computer Engineering Faculty Publications
Low temperature plasmas (LTPs) enable to create a highly reactive environment at near ambient temperatures due to the energetic electrons with typical kinetic energies in the range of 1 to 10 eV (1 eV = 11600K), which are being used in applications ranging from plasma etching of electronic chips and additive manufacturing to plasma-assisted combustion. LTPs are at the core of many advanced technologies. Without LTPs, many of the conveniences of modern society would simply not exist. New applications of LTPs are continuously being proposed. Researchers are facing many grand challenges before these new applications can be translated to practice. …
A Laser Frequency Transverse Modulation Might Compensate For The Spectral Broadening Due To Large Electron Energy Spread In Thomson Sources, Vittoria Petrillo, Illya Drebot, Geoffrey Krafft, Cesare Maroli, Andrea R. Rossi, Marcello Rossetti Conti, Marcel Ruijter, Balša Terzić
A Laser Frequency Transverse Modulation Might Compensate For The Spectral Broadening Due To Large Electron Energy Spread In Thomson Sources, Vittoria Petrillo, Illya Drebot, Geoffrey Krafft, Cesare Maroli, Andrea R. Rossi, Marcello Rossetti Conti, Marcel Ruijter, Balša Terzić
Physics Faculty Publications
Compact laser plasma accelerators generate high-energy electron beams with increasing quality. When used in inverse Compton backscattering, however, the relatively large electron energy spread jeopardizes potential applications requiring small bandwidths. We present here a novel interaction scheme that allows us to compensate for the negative effects of the electron energy spread on the spectrum, by introducing a transverse spatial frequency modulation in the laser pulse. Such a laser chirp, together with a properly dispersed electron beam, can substantially reduce the broadening of the Compton bandwidth due to the electron energy spread. We show theoretical analysis and numerical simulations for hard …
Cross-Section Measurement Of Virtual Photoproduction Of Iso-Triplet Three-Body Hypernucleus, ⋀Nn, T. Gogami, K. N. Suzuki, B. Pandey, K. Itabashi, S. Nagao, K. Okuyama, S. N. Nakamura, L. Tang, D. Abrams, T. Akiyama, D. Androic, K. Aniol, C. Ayerbe Gayoso, J. Bane, S. Barcus, J. Barrow, V. Bellini, H. Bhatt, D. Bhetuwal, D. Biswas, A. Camsonne, J. Castellanos, J-P. Chen, J. Chen, S. Covrig, D. Chrisman, R. Cruz-Torres, R. Das, E. Fuchey, K. Gnanvo, F. Garibaldi, T. Gautam, J. Gomez, P. Gueye, T.J. Hague, O. Hansen, W. Henry, F. Hauenstein, D. W. Higinbotham, C. E. Hyde, M. Kaneta, C. Keppel, T. Kutz, N. Lashley-Colthirst, S. Li, H. Liu, J. Mammei, P. Markowitz, R. E. Mcclellan, F. Meddi, D. Meekins, R. Michaels, M. Mihovilovic, A. Moyer, D. Nguyen, M. Nycz, V. Owen, C. Palatchi, S. Park, T. Petkovic, S. Premathilake, P.E. Reimer, J. Reinhold, S. Riordan, V. Rodriguez, C. Samanta, S. N. Santiesteban, B. Sawatzky, S. Širca, K. Slifer, T. Su, Y. Tian, Y. Toyama, K. Uehara, G. M. Urciuoli, D. Votaw, J. Williamson, B. Wojtsekhowski, S. A. Wood, B. Yale, Z. Ye, J. Zhang, X. Zheng
Cross-Section Measurement Of Virtual Photoproduction Of Iso-Triplet Three-Body Hypernucleus, ⋀Nn, T. Gogami, K. N. Suzuki, B. Pandey, K. Itabashi, S. Nagao, K. Okuyama, S. N. Nakamura, L. Tang, D. Abrams, T. Akiyama, D. Androic, K. Aniol, C. Ayerbe Gayoso, J. Bane, S. Barcus, J. Barrow, V. Bellini, H. Bhatt, D. Bhetuwal, D. Biswas, A. Camsonne, J. Castellanos, J-P. Chen, J. Chen, S. Covrig, D. Chrisman, R. Cruz-Torres, R. Das, E. Fuchey, K. Gnanvo, F. Garibaldi, T. Gautam, J. Gomez, P. Gueye, T.J. Hague, O. Hansen, W. Henry, F. Hauenstein, D. W. Higinbotham, C. E. Hyde, M. Kaneta, C. Keppel, T. Kutz, N. Lashley-Colthirst, S. Li, H. Liu, J. Mammei, P. Markowitz, R. E. Mcclellan, F. Meddi, D. Meekins, R. Michaels, M. Mihovilovic, A. Moyer, D. Nguyen, M. Nycz, V. Owen, C. Palatchi, S. Park, T. Petkovic, S. Premathilake, P.E. Reimer, J. Reinhold, S. Riordan, V. Rodriguez, C. Samanta, S. N. Santiesteban, B. Sawatzky, S. Širca, K. Slifer, T. Su, Y. Tian, Y. Toyama, K. Uehara, G. M. Urciuoli, D. Votaw, J. Williamson, B. Wojtsekhowski, S. A. Wood, B. Yale, Z. Ye, J. Zhang, X. Zheng
Physics Faculty Publications
Missing-mass spectroscopy with the 3H(e, e′K+) reaction was carried out at Jefferson Lab’s (JLab) Hall A in Oct–Nov, 2018. The differential cross section for the 3H(γ∗, K+)Λnn was deduced at ω = Ee − Ee′ = 2.102 GeV and at the forward K+-scattering angle (0° ≤ θγ∗K ≤ 5°) in the laboratory frame. Given typical predicted energies and decay widths, which are (BΛ, Γ) = (−0.25, 0.8) and (−0.55, 4.7) MeV, the cross sections were found …
Direct Current Magnetic Hall Probe Technique For Measurement Of Field Penetration In Thin Film Superconductors For Superconducting Radio Frequency Resonators, Iresha Harshani Senevirathne, Alex Gurevich, Jean Delayen
Direct Current Magnetic Hall Probe Technique For Measurement Of Field Penetration In Thin Film Superconductors For Superconducting Radio Frequency Resonators, Iresha Harshani Senevirathne, Alex Gurevich, Jean Delayen
Physics Faculty Publications
Superconducting Radio Frequency (SRF) cavities used in particle accelerators are typically formed from or coated with superconducting materials. Currently, high purity niobium is the material of choice for SRF cavities that have been optimized to operate near their theoretical field limits. This brings about the need for significant R & D efforts to develop next generation superconducting materials that could outperform Nb and keep up with the demands of new accelerator facilities. To achieve high quality factors and accelerating gradients, the cavity material should be able to remain in the superconducting Meissner state under a high RF magnetic field without …