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FIU Electronic Theses and Dissertations

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Full-Text Articles in Physics

Study Of The Etaprimepi0 System In Gluex, Rupesh Dotel Jun 2022

Study Of The Etaprimepi0 System In Gluex, Rupesh Dotel

FIU Electronic Theses and Dissertations

The η′π is an important decay channel for the potentially exotic hybrid meson π1(1600) that has been detected in the COMPASS, VES and E852 experiments. These previous experiments used a charged pion beam as a probe. In contrast, the GlueX experiment is designed to search for the exotic hybrid mesons using a linearly polarized photon beam. This thesis project analyzes the η′π0 system produced in GlueX by the reaction γp → η′π0p. After optimizing the event selection to minimize background contributions, a mass independent partial wave analysis is performed in search of an exotic signature. Within the currently available statistical …


The Role Of Conformational Changes In Viral And Bacterial Protein Functions, Md Lokman Hossen Jun 2022

The Role Of Conformational Changes In Viral And Bacterial Protein Functions, Md Lokman Hossen

FIU Electronic Theses and Dissertations

Proteins do versatile work in cells. They require a cascade of structural changes to perform different tasks like binding to the other neighboring biomolecules, transporting small chemicals, activating a chemical reaction, etc. The structural conformations of proteins can be critical in changing their working ability. In this dissertation, I investigated the role of conformational changes of viral protein, e.g., spike and envelope protein of SARS-CoV-2, and bacterial protein, e.g., multidrug transporter and toxic extrusion protein- PfMATE from Pyrococcus furiosus. Also, I performed molecular docking-based drug screening targeting the E protein to suggest a set of drugs that can be repurposed …


The Valence Quark Structure Of The Nucleon, Christopher A. Leon May 2022

The Valence Quark Structure Of The Nucleon, Christopher A. Leon

FIU Electronic Theses and Dissertations

The nucleon is a composite object, formed from a sea of quarks, anti-quarks and gluons being continuously created and annihilated. Among this complexity, however, there are three valence quarks that give the nucleon its baryon and flavor numbers. Here we investigate the dynamical structure of valence quarks inside the nucleon. The primary tool used will be patron distribution functions (PDFs), which give the distribution of momentum fraction, x, of the quarks and gluons inside the nucleon. By examining the PDFs of the valence quarks from phenomenological fits, we derive a new model-independent relation of PDF peaks and connect it to …


In Silico Identification Of Vaccine Candidates Against Viral Infections, Prabin Baral Mar 2022

In Silico Identification Of Vaccine Candidates Against Viral Infections, Prabin Baral

FIU Electronic Theses and Dissertations

There are many viral diseases without effective treatments or vaccines. These viruses can cause catastrophic epidemics such as the Lassa, Ebola, and Marburg viruses. Similarly, the recent coronavirus pandemic is of great concern as new variants are continuously emerging with decreased susceptibility to antibodies and vaccines that were developed for earlier strains. A critical step in the immune system’s fight against viruses involves an immunological protein molecule binding to a viral protein molecule. I investigate the atomic and molecular details of binding site recognition and binding interactions and dynamics for three important viruses.

Antigens are molecules, such as viral proteins, …


Temperature Dependent Protein-Chromophore Hydrogen Bond Dynamics In The Far-Red Fluorescent Proteins By Using Molecular Dynamics Simulation And Quantum Calculationtemperature Dependent Protein-Chromophore Hydrogen Bond Dynamics In The Far-Red Fluorescent Proteins By Using Molecular Dynamics Simulation And Quantum Calculation, Chandra Prasad Dhakal Nov 2021

Temperature Dependent Protein-Chromophore Hydrogen Bond Dynamics In The Far-Red Fluorescent Proteins By Using Molecular Dynamics Simulation And Quantum Calculationtemperature Dependent Protein-Chromophore Hydrogen Bond Dynamics In The Far-Red Fluorescent Proteins By Using Molecular Dynamics Simulation And Quantum Calculation, Chandra Prasad Dhakal

FIU Electronic Theses and Dissertations

Fluorescent proteins are valuable tools as biochemical markers in molecular and cell biology research for studying cellular processes. Red Fluorescent Proteins (RFPs) are highly desirable for in vivo applications in living cell imaging because they absorb and emit light in the red region of the spectrum where cellular autofluorescence. Naturally occurring fluorescent proteins with emission peaks in this region of the spectrum occur in dimeric or tetrameric forms. For their use as biochemical markers, several monomeric variants of RFP have been developed which include mCherry, dsRed, and mStrawberry. Far red-emitting FPs with large Stokes shift are especially valuables for in …


Optical Two-Dimensional Coherent Spectroscopy Of Many-Body Dynamics In Quantum Materials, Maria Fernanda Munoz Aug 2021

Optical Two-Dimensional Coherent Spectroscopy Of Many-Body Dynamics In Quantum Materials, Maria Fernanda Munoz

FIU Electronic Theses and Dissertations

Since the rise of the concept of quantum materials (QM), these materials described as many-body quantum systems (interacting atoms, molecules, or electrons) have been suitable for many optoelectronic and quantum applications. Additionally, there has been significant interest in the research of QM to understand the underlying physics behind their extraordinary optical properties. Examples of QM are ultracold atoms, layered 2D semiconductors, supramolecular materials, and more. In 2012, a high energy conversion efficiency of over 10% was reported for the first time for metal-halide perovskite (MHP) solar cells, opening a new era for photovoltaics research. The reported efficiencies have been improved …


Probing The Structure Of Deuteron At Very Short Distances, Frank Vera Jul 2021

Probing The Structure Of Deuteron At Very Short Distances, Frank Vera

FIU Electronic Theses and Dissertations

We study the electro-disintegration of deuteron at quasi-elastic kinematics and high transferred momentum as a probe for the short distance structure in nuclei. In this reaction, an electron hits a nucleus of deuterium, which breaks up into a pair of nucleons (proton-neutron). We focus our attention on events where fast nucleons emerge, corresponding to nuclear configurations where the bound nucleons have a high relative momentum (exceeding 700 MeV/c). The present research is relevant to physical systems where high-density nuclear matter is present. This condition covers a wide range of physics, from neutron stars to nuclei stability and the repulsive nuclear …


A Study Of Magnetism And Possible Mixed-State Superconductivity In Phosphorus-Doped Graphene, Julian E. Gil Pinzon Jun 2021

A Study Of Magnetism And Possible Mixed-State Superconductivity In Phosphorus-Doped Graphene, Julian E. Gil Pinzon

FIU Electronic Theses and Dissertations

Evidence of superconducting vortices, and consequently mixed-state superconductivity, has been observed in phosphorus-doped graphene at temperatures as high as 260 K. The evidence includes transport measurements in the form of resistance versus temperature curves, and magnetic measurements in the form of susceptibility and magnetic Nernst effect measurements. The drops in resistance, periodic steps in resistance, the appearance of Nernst peaks and hysteresis all point to phosphorus-doped graphene having a broad resistive region due to flux flow as well as a Berezinskii-Kosterlitz-Thouless (BKT) transition at lower temperatures.

The observation of irreversible behavior in phosphorus-doped graphene under the influence of a thermal …


Structural Dynamics Of Membrane Interacting Viral Proteins, Nisha Bhattarai May 2021

Structural Dynamics Of Membrane Interacting Viral Proteins, Nisha Bhattarai

FIU Electronic Theses and Dissertations

Viruses do not possess complete cellular machinery but have the ability to reproduce by utilizing cellular machinery inside host cells. They are nanoscale machines that rapidly modify (evolve) their molecular components to cause disease and death. Therefore, emergence of deadly infectious viruses is a monumental health concern and understanding how viruses are able to enter, replicate, assemble and egress from the host cell is important to mitigate the threat.

A fully active, infectious viral structure is known as a virion. A virion contains genetic material and is enclosed by a capsid. The capsid is a protein shell and some viruses …


Electron Field Emission And Electrochemical Lithiation Properties Of Vertically Aligned Carbon Nanotube Arrays Grown Directly On Metal Substrates, Arun Thapa Mar 2021

Electron Field Emission And Electrochemical Lithiation Properties Of Vertically Aligned Carbon Nanotube Arrays Grown Directly On Metal Substrates, Arun Thapa

FIU Electronic Theses and Dissertations

Carbon nanotubes (CNTs) represent one of the critical inventions that have triggered new science and technology in many fields because of their distinctive mechanical, thermal, electrical, electrochemical, and optical properties. Despite the tremendous potential of CNTs, challenges in synthesizing and processing continue to hinder their applications. This dissertation is devoted to synthesizing vertically aligned CNT arrays on metal substrates via plasma-enhanced chemical vapor deposition and the study of their electron field emission (FE) and electrochemical lithiation properties.

Vertically aligned CNTs (VACNTs) are promising electron field emitters for vacuum micro/nano-electronics. Improved control over the morphology and a successful direct-growth of the …


Photo-Production Of Eta Mesons, Mahmoud Mohamed Kamel Nov 2020

Photo-Production Of Eta Mesons, Mahmoud Mohamed Kamel

FIU Electronic Theses and Dissertations

In this work we present the GlueX experiment extensive high statistics measurements of the η meson photo-production differential cross sections at beam energies between 3 GeV and 11.6 GeV. We compared the low energy (2.9 GeV< Eγ < 5.9 GeV) differential cross section (dσ/dΩ) results to previous experimental results from the Continuous Electron Beam Accelerator Facility (CEBAF) Large Acceptance Spectrometer (CLAS) collaboration. These (dσ/dΩ) results are also compared to the theoretical isobar model EtaMAID2018 by Tiator et. al., and the Regge model by Nys et. al. The differential cross section dσ/dt is also presented and compared to the previous experimental results, and to the above models, in addition to a model by J. M. Laget. The high energy (6.2 GeV< Eγ < 11.6 GeV) cross section results (dσ/dΩ, and dσ/dt) are compared to the isobar model EtaMAID2018. These results will provide new constraints on η photo-production mechanisms and high energy t- channel processes.


Organic-Inorganic Halide Perovskite Nanocrystals And Solar Cells, Rui Guo Nov 2020

Organic-Inorganic Halide Perovskite Nanocrystals And Solar Cells, Rui Guo

FIU Electronic Theses and Dissertations

A great challenge facing humanity in the 21st century is finding inexhaustible and inexpensive energy sources to power the planet. Renewable energies are the best solutions because of their abundance, diversity, and pollution-free emission. Solar energy is the cleanest and most abundant renewable energy source available. In the continuing quest for efficient and low-cost solar cells, perovskite solar cells (PSCs) have emerged as a potential replacement for silicon solar cells. Since 2009, the record efficiencies of PSCs have been skyrocketing from 3.8 % to 25.2 % and are now approaching the theoretical limit. Along with the three-dimensional perovskites used …


Surface-Enhanced Raman Spectroscopy For Single Molecule Analysis And Biological Application, Jing Guo Oct 2020

Surface-Enhanced Raman Spectroscopy For Single Molecule Analysis And Biological Application, Jing Guo

FIU Electronic Theses and Dissertations

Surface-enhanced Raman spectroscopy (SERS) is a surface analytical technique, which enhances the Raman signal based on the localized surface plasmon resonance (LSPR) phenomenon. It has been successfully used for single molecule (SM) detection and has extended SERS to numerous applications in biomolecular detection. However, SM detection by SERS is still challenging especially with traditional SERS substrates and detection methods. In addition, the fundamental understanding of the SERS enhancement mechanism is still elusive. Furthermore, the application of SERS in biological field is still in the early stage. To address these challenges, there are two main aspects of SERS studied in my …


Investigations Of Cell-Penetrating And Membrane-Pore Forming Peptides, Rudramani Pokhrel Oct 2020

Investigations Of Cell-Penetrating And Membrane-Pore Forming Peptides, Rudramani Pokhrel

FIU Electronic Theses and Dissertations

Cell-penetrating and membrane-pore forming peptides are a class of membrane-active peptides. They are short sequence peptides having both hydrophilic and lipophilic combinations of amino acids. These peptides can have contrast functional diversity. Peptides encoded by viruses function as viroporins and play a critical role in viral replication, propagation, and pathogenesis. One such peptide is the Ebola virus delta peptide, which forms a pore in the host cell membrane. Another set of pore-forming peptides are antimicrobial Lantibiotic peptides that may be useful for killing antibiotic resistant bacteria by disrupting the bacterial membrane through two different possible mechanisms. Not only can they …


Cross Section Measurements Of Deuteron Electro-Disintegration At Very High Recoil Momenta And Large 4-Momentum Transfers (Q2), Carlos Yero Jul 2020

Cross Section Measurements Of Deuteron Electro-Disintegration At Very High Recoil Momenta And Large 4-Momentum Transfers (Q2), Carlos Yero

FIU Electronic Theses and Dissertations

The 2H(e,e′p)n cross sections have been measured at negative 4-momentum transfers of Q2 = 4.5±0.5 (GeV/c)2 and Q2 = 3.5±0.5 (GeV/c)2 reaching neutron recoil (missing) momenta up to pr ∼1.0 GeV/c. The data have been obtained at fixed neutron recoil angles 5o ≤ θnq ≤ 95o with respect to the 3-momentum transfer q. The new data agree well with the previous data which reached pr ∼ 500 MeV/c. At θnq = 35o and 45o, final state interactions (FSI), meson exchange currents (MEC) and isobar configurations (IC) …


Multifunctional Nanopipette For Single Nanoparticles And Proteins Analysis, Popular Pandey Jun 2020

Multifunctional Nanopipette For Single Nanoparticles And Proteins Analysis, Popular Pandey

FIU Electronic Theses and Dissertations

Complex biological processes occur in the nanoscale (1-100 nm) regime. ‘DNA’ which is just 2 nm in dimension is a fundamental building block of all life. ‘Hemoglobin’, a blood protein that transports oxygen throughout our body is only 5 nm in diameter. Importantly, the structure, composition, and dynamics of these nanoscale entities determine their biological function. A slight alteration in the structure and composition can lead to the malfunction of the protein which is key to various diseases including cancer. Therefore, the single-molecule measurement approach is essential to characterize both the average properties and the rare …


The Impacts Of Small Group Interactions And Social Interdependence In Introductory Physics, Miguel Angel Rodriguez Velazquez Jun 2020

The Impacts Of Small Group Interactions And Social Interdependence In Introductory Physics, Miguel Angel Rodriguez Velazquez

FIU Electronic Theses and Dissertations

The collected works in my dissertation are centered around the dynamics and impacts of small group learning in introductory physics. It is motivated by a desire to better understand which classroom practices and learning processes may lead to students achieving greater understanding or affinity to physics. Several theoretical frameworks are leveraged in my work including physics identity theory, social interdependence theory and social metacognition. The research design employed quantitative and qualitative methods including regression analysis, descriptive statistics, and observational analysis.

Firstly, students across the U.S. enrolled in first semester introductory physics courses were surveyed at the beginning and end of …


Charged Fusion Product Plasma Diagnostics In Spherical Tokamaks, Alexander Netepenko Nov 2019

Charged Fusion Product Plasma Diagnostics In Spherical Tokamaks, Alexander Netepenko

FIU Electronic Theses and Dissertations

Charged fusion products from the D(d,p)t reaction, protons (p) and tritons (t), can be detected to obtain time and position dependent information on the fusion reaction profile in plasmas heated with neutral particles beams. We have developed a prototype instrument consisting of charged particle detectors with ion-implanted-silicon surface barrier detectors. Each detector is combined with two replaceable collimators in such a way that it can accept protons and tritons emitted from a well-defined area inside the plasma. The detectors thus provide curved views across the plasma volume.

Combining the data of all six detectors allows one to study changes in …


Coherent And Incoherent Dynamics Of Quasiparticles In Monolayer Molybdenum Diselenide, Michael Titze Mar 2019

Coherent And Incoherent Dynamics Of Quasiparticles In Monolayer Molybdenum Diselenide, Michael Titze

FIU Electronic Theses and Dissertations

Monolayer Materials, especially single-layer graphite, called graphene, as the first synthesized and most prominent representative, have attracted significant research interest since its discovery in 2004. The efforts were rewarded with a Nobel prize in 2010 for the discovery of graphene, the same year in which the first monolayer transition metal dichalcogenide (ML-TMD) was found to have a direct bandgap. In contrast to graphene ML-TMDs have a direct bandgap in the visible or near-infrared spectral range, making them ideally suited for optoelectronic device applications. Explicit inversion symmetry breaking of the unit cell in ML-TMDs furthermore leads to a new interesting property, …


Exploring The Neural Mechanisms Of Physics Learning, Jessica E. Bartley Nov 2018

Exploring The Neural Mechanisms Of Physics Learning, Jessica E. Bartley

FIU Electronic Theses and Dissertations

This dissertation presents a series of neuroimaging investigations and achievements that strive to deepen and broaden our understanding of human problem solving and physics learning. Neuroscience conceives of dynamic relationships between behavior, experience, and brain structure and function, but how neural changes enable human learning across classroom instruction remains an open question. At the same time, physics is a challenging area of study in which introductory students regularly struggle to achieve success across university instruction. Research and initiatives in neuroeducation promise a new understanding into the interactions between biology and education, including the neural mechanisms of learning and development. These …


Polarization Observables For Γp −> K+Λ At Photon Energies Up To 5.45 Gev, Shankar Dayal Adhikari Nov 2018

Polarization Observables For Γp −> K+Λ At Photon Energies Up To 5.45 Gev, Shankar Dayal Adhikari

FIU Electronic Theses and Dissertations

Excited nucleon states are established as an important milestone to understand quantum chromodynamics in the non-perturbative region. Even after decades of study, not all of the excited states predicted by different theoretical approaches have been verified. The disparity between the predicted states and the verified states is known as the “missing baryon problem". The verified states were mostly established using pion beam data or through Nπ decay channels, but are not sufficient to address the missing baryon problem. In recent years, new experiments were conducted worldwide at CLAS in Jefferson Lab, ELSA in Bonn, MAMI in Mainz, and so on, …


Qcd Process In Few Nucleon Systems, Dhiraj Maheswari Jun 2018

Qcd Process In Few Nucleon Systems, Dhiraj Maheswari

FIU Electronic Theses and Dissertations

One of the important issues of Quantum Chromodynamics (QCD) - the fundamental theory of strong interaction, is the understanding of the role of the quark-gluon interactions in the processes involving nuclear targets. One direction in such studies is to explore the onset of the quark gluon degrees of freedom in nuclear dynamics. The other direction is using the nuclear targets as a “micro-labs” in studies of the QCD processes involving protons and neutrons bound in the nucleus. In the proposed research, we work in both directions considering high energy photo- and electro-production reactions involving deuteron and 3 He nuclei.

In …


Search For Supersymmetry In Proton-Proton Collisions At 13 Tev With The Cms Detector Using Identified Top Quarks, Yagya R. Joshi Jun 2018

Search For Supersymmetry In Proton-Proton Collisions At 13 Tev With The Cms Detector Using Identified Top Quarks, Yagya R. Joshi

FIU Electronic Theses and Dissertations

A search for supersymmetry is presented based on proton-proton collision events containing identified hadronically decaying top quarks (i.e., events with no identified leptons), and an imbalance EmissT in transverse momentum. The data were collected with the Compact Muon Solenoid (CMS) detector at the CERN Large Hadron Collider (LHC) at a center-of-mass energy of 13 TeV, and correspond to an integrated luminosity of 35.9 fb-1. The 84 exclusive search regions are defined in terms of the multiplicity of bottom quark jet and top quark candidates, the missing energy, the scalar sum of jet transverse momenta HT, and …


Examining Students' Representation Choices In University Modeling Instruction, Daryl Mcpadden Mar 2018

Examining Students' Representation Choices In University Modeling Instruction, Daryl Mcpadden

FIU Electronic Theses and Dissertations

Representations (such as pictures, diagrams, word descriptions, equations, etc.) are critical tools for learning, problem solving, and communicating in science, particularly in physics where multiple representations often serve as intermediate steps, a means to evaluate a solution, and highlight different aspects a physical phenomenon. This dissertation explores the representation choices made by students in the University Modeling Instruction (MI) courses on problems from across introductory physics content. Modeling Instruction is a two-semester introductory, calculus-based physics sequence that was designed to guide students through the process of building, testing, applying, and refining models. As a part of this modeling cycle, students …


Antibaryon Photoproduction Using Clas At Jefferson Lab, William B. Phelps Nov 2017

Antibaryon Photoproduction Using Clas At Jefferson Lab, William B. Phelps

FIU Electronic Theses and Dissertations

Antibaryon production has been investigated since the advent of nuclear

physics, largely motivated by the potential for baryon-antibaryon bound states.

Due to the recent availability of high statistics experiments there has been a

renewed interest in how antibaryons are created in photoproduction. The g12

(E04-005) experiment conducted at Thomas Jefferson National Accelerator Fa-

cility used the CEBAF Large Acceptance Spectrometer to provide the world’s

largest dataset for baryon-antibaryon photoproduction on a liquid hydrogen tar-

get. The focus of this work is to investigate the photoproduction mechanism of

γp → ppp ̄ through detailed differential cross section measurements from 3.95

to …


Folding Of Bovine Pancreatic Trypsin Inhibitor (Bpti) Is Faster Using Aromatic Thiols And Their Corresponding Disulfides, Ram Prasad Marahatta Nov 2017

Folding Of Bovine Pancreatic Trypsin Inhibitor (Bpti) Is Faster Using Aromatic Thiols And Their Corresponding Disulfides, Ram Prasad Marahatta

FIU Electronic Theses and Dissertations

Improvement in the in vitro oxidative folding of disulfide-containing proteins, such as extracellular and pharmaceutically important proteins, is required. Traditional folding methods using small molecule aliphatic thiol and disulfide, such as glutathione (GSH) and glutathione disulfide (GSSG) are slow and low yielding. Small molecule aromatic thiols and disulfides show great potentiality because aromatic thiols have low pKa values, close to the thiol pKa of protein disulfide isomerase (PDI), higher nucleophilicity and good leaving group ability. Our studies showed that thiols with a positively charged group, quaternary ammonium salts (QAS), are better than thiols with negatively charged groups such as phosphonic …


Examining The Relationships Between Gender Role Congruity, Identity, And The Choice To Persist For Women In Undergraduate Physics Majors, Bronwen Bares Pelaez Nov 2017

Examining The Relationships Between Gender Role Congruity, Identity, And The Choice To Persist For Women In Undergraduate Physics Majors, Bronwen Bares Pelaez

FIU Electronic Theses and Dissertations

Persistent gender disparity limits the available contributors to advancing some science, technology, engineering, and math (STEM) fields. While higher education can be an influential time-point for ensuring adequate participation, many physics programs across the U.S. have few women in classroom or lab settings. Prior research indicates that these women face considerable barriers. For university students, faculty, and administration to appropriately address these issues, it is important to understand the experiences of women as they navigate male-dominated STEM fields.

This explanatory sequential mixed methods study explored undergraduate female physics majors’ experiences with their male-dominated academic and research spaces in the U.S. …


Resilient And Real-Time Control For The Optimum Management Of Hybrid Energy Storage Systems With Distributed Dynamic Demands, Christopher R. Lashway Oct 2017

Resilient And Real-Time Control For The Optimum Management Of Hybrid Energy Storage Systems With Distributed Dynamic Demands, Christopher R. Lashway

FIU Electronic Theses and Dissertations

A continuous increase in demands from the utility grid and traction applications have steered public attention toward the integration of energy storage (ES) and hybrid ES (HESS) solutions. Modern technologies are no longer limited to batteries, but can include supercapacitors (SC) and flywheel electromechanical ES well. However, insufficient control and algorithms to monitor these devices can result in a wide range of operational issues. A modern day control platform must have a deep understanding of the source. In this dissertation, specialized modular Energy Storage Management Controllers (ESMC) were developed to interface with a variety of ES devices. The EMSC provides …


Describing And Mapping The Interactions Between Student Affective Factors Related To Persistence In Science, Physics, And Engineering, Jacqueline Doyle Jun 2017

Describing And Mapping The Interactions Between Student Affective Factors Related To Persistence In Science, Physics, And Engineering, Jacqueline Doyle

FIU Electronic Theses and Dissertations

This dissertation explores how students’ beliefs and attitudes interact with their identities as physics people, motivated by calls to increase participation in science, technology, engineering, and mathematics (STEM) careers. This work combines several theoretical frameworks, including Identity theory, Future Time Perspective theory, and other personality traits to investigate associations between these factors. An enriched understanding of how these attitudinal factors are associated with each other extends prior models of identity and link theoretical frameworks used in psychological and educational research. The research uses a series of quantitative and qualitative methodologies, including linear and logistic regression analysis, thematic interview analysis, and …


Behavioral And Neural Mechanisms Of Social Heterogeneity In Attention Deficit/Hyperactivity Disorder, Kailey Macnamara Jun 2017

Behavioral And Neural Mechanisms Of Social Heterogeneity In Attention Deficit/Hyperactivity Disorder, Kailey Macnamara

FIU Electronic Theses and Dissertations

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common child-onset neurodevelopment disorders, affecting 5% of children in the United States (American Psychiatric Association, 2013). Treatment matching in ADHD is difficult and unsatisfactory; the same general treatment algorithm is recommended for all children. It is therefore important to consider the development of specialized treatment programs based on a variety of behavioral and neurological biomarkers. Unfortunately, due to its multi-faceted classification, the heterogeneity of this behavioral disorder is under-investigated (Costa Dias et al., 2015). Scientific research in this area is especially limited as the severity of ADHD goes undiagnosed, children tend to …