Physics Commons^™

Utilizing Log Files For Treatment Planning And Delivery Qa In Radiotherapy, Carl W. Stanhope

Wayne State University Theses

Purpose: Monte Carlo-based log file quality assurance (LF-MC QA) is investigated as an alternative method to phantom-based patient-specific quality assurance in radiotherapy (e.g. ArcCHECK QA (AC QA)).

Methods: First, the shortcomings of AC QA were investigated. The sensitivity dependence of ArcCHECK diodes on dose rate (in-field) and energy (primarily out-of-field) was quantified. LF-MC QA was then analyzed on the phantom geometry. Planned (‘Plan’) and LF-reconstructed CS and MC doses were compared with each other and AC measurement via statistical (mean ± StdDev(σ)) and gamma analyses to isolate dosimetric uncertainties and quantify the relative accuracies of AC QA and LF-MC QA. …

Force Field Development With Gomc A Fast New Monte Carlo Molecular Simulation Code, Jason Richard Mick

Wayne State University Dissertations

In this work GOMC (GPU Optimized Monte Carlo) a new fast, flexible, and free molecular Monte Carlo code for the simulation atomistic chemical systems is presented. The results of a large Lennard-Jonesium simulation in the Gibbs ensemble is presented. Force fields developed using the code are also presented. To fit the models a quantitative fitting process is outlined using a scoring function and heat maps. The presented n-6 force fields include force fields for noble gases and branched alkanes. These force fields are shown to be the most accurate LJ or n-6 force fields to date for these compounds, capable …