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SelectedWorks

Selected Works

2013

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Articles 31 - 38 of 38

Full-Text Articles in Physics

Microfabricated Nanotopological Surfaces For Study Of Adhesion-Dependent Cell Mechanosensitivity, Weiqiang Chen, Yubing Sun, Jianping Fu Jan 2013

Microfabricated Nanotopological Surfaces For Study Of Adhesion-Dependent Cell Mechanosensitivity, Weiqiang Chen, Yubing Sun, Jianping Fu

Weiqiang Chen

Cells exhibit high sensitivity and diverse responses to the intrinsic nanotopography of the extracellular matrix through their nanoscale cellular sensing machinery. A simple microfabrication method for precise control and spatial patterning of the local nanoroughness on glass surfaces by using photolithography and reactive ion etching is reported. It is demonstrated that local nanoroughness as a biophysical cue could regulate a diverse array of NIH/3T3 fi broblast behaviors, including cell morphology, adhesion, proliferation, migration, and cytoskeleton contractility. The capability to control and further predict cellular responses to nanoroughness might suggest novel methods for developing biomaterials mimicking nanotopographic structures in vivo for …


Surface-Micromachined Microfiltration Membranes For Efficient Isolation And Functional Immunophenotyping Of Subpopulations Of Immune Cells, Weiqiang Chen, Nien-Tsu Huang, Boram Oh, Raymond H. W. Lam, Rong Fan, Timothy T. Cornell, Thomas P. Shanley, Katsuo Kurabayashi, Jianping Fu Jan 2013

Surface-Micromachined Microfiltration Membranes For Efficient Isolation And Functional Immunophenotyping Of Subpopulations Of Immune Cells, Weiqiang Chen, Nien-Tsu Huang, Boram Oh, Raymond H. W. Lam, Rong Fan, Timothy T. Cornell, Thomas P. Shanley, Katsuo Kurabayashi, Jianping Fu

Weiqiang Chen

An accurate measurement of the immune status in patients with immune system disorders is critical in evaluating the stage of diseases and tailoring drug treatments. The functional cellular immunity test is a promising method to establish the diagnosis of immune dysfunctions. The conventional functional cellular immunity test involves measurements of the capacity of peripheral blood mononuclear cells to produce pro-inflammatory cytokines when stimulated ex vivo. However, this “bulk” assay measures the overall reactivity of a population of lymphocytes and monocytes, making it difficult to pinpoint the phenotype or real identity of the reactive immune cells involved. In this research, we …


Bps One-Branes In Five Dimensions, Moataz Emam Jan 2013

Bps One-Branes In Five Dimensions, Moataz Emam

Moataz Emam

In a recent paper, we studied the scalar fields of the five dimensional N=2 hypermultiplets using the method of symplectic covariance. For static spherically symmetric backgrounds, we showed that exactly two possibilities exist and detailed one of them. In this paper, we present the second case: Bogomol'nyi-Prasad-Sommerfield (BPS) one-branes carrying charge under the hypermultiplets. We find an explicitly symplectic solution of the fields in this background and derive the conditions required for a full spacetime understanding.


The Five Dimensional Universal Hypermultiplet And The Cosmological Constant Problem, Moataz Emam, Charles Canestaro Jan 2013

The Five Dimensional Universal Hypermultiplet And The Cosmological Constant Problem, Moataz Emam, Charles Canestaro

Moataz Emam

We model the universe as a 3-brane embedded in five dimensional spacetime with N=2 supersymmetry. The presence of the scalar fields of the universal hypermultiplet in the bulk results in a positive pressure effectively reducing the value of the cosmological constant and thereby providing a possible answer as to why the measured value of the cosmological constant is many orders of magnitude smaller than predicted from the vacuum energy. The solution allows for any number of parallel branes to exist and relates their cosmological constants (as well as matter densities and radiation pressures) to the value of the dilaton in …


Mechaniczny Rozdział Faz Proj., Wojciech M. Budzianowski Jan 2013

Mechaniczny Rozdział Faz Proj., Wojciech M. Budzianowski

Wojciech Budzianowski

No abstract provided.


Challenges And Prospects Of Processes Utilising Carbonic Anhydrase For Co2 Separation, Patrycja Szeligiewicz, Wojciech M. Budzianowski Jan 2013

Challenges And Prospects Of Processes Utilising Carbonic Anhydrase For Co2 Separation, Patrycja Szeligiewicz, Wojciech M. Budzianowski

Wojciech Budzianowski

This article provides an analysis of processes for separation CO2 by using carbonic anhydrase enzyme with particular emphasis on reactive-membrane solutions. Three available processes are characterised. Main challenges and prospects are given. It is found that in view of numerous challenges practical applications of these processes will be difficult in near future. Further research is therefore needed for improving existing processes through finding methods for eliminating their main drawbacks such as short lifetime of carbonic anhydrase or low resistance of reactive membrane systems to impurities contained in flue gases from power plants.


Students Talk About Energy In Project- Based Inquiry Science, Benedikt W. Harrer, Virginia J. Flood, Michael C. Wittmann Jan 2013

Students Talk About Energy In Project- Based Inquiry Science, Benedikt W. Harrer, Virginia J. Flood, Michael C. Wittmann

Benedikt W. Harrer

We examine the types of emergent language eighth grade students in rural Maine middle schools use when they discuss energy in their first experiences with Project-Based Inquiry Science: Energy, a research-based curriculum that uses a specific language for talking about energy. By comparative analysis of the language used by the curriculum materials to students’ language, we find that students’ talk is at times more aligned with a Stores and Transfer model of energy than the Forms model supported by the curriculum.


Productive Resources In Students’ Ideas About Energy: An Alternative Analysis Of Watts’ Original Interview Transcripts, Benedikt W. Harrer, Virginia J. Flood, Michael C. Wittmann Jan 2013

Productive Resources In Students’ Ideas About Energy: An Alternative Analysis Of Watts’ Original Interview Transcripts, Benedikt W. Harrer, Virginia J. Flood, Michael C. Wittmann

Benedikt W. Harrer

For over 30 years, researchers have investigated students’ ideas about energy with the intent of reforming instructional practice. In this pursuit, Watts contributed an influential study with his 1983 paper “Some alternative views of energy” [Phys. Educ. 18, 213 (1983)]. Watts’ “alternative frameworks” continue to be used for categorizing students’ non-normative ideas about energy. Using a resources framework, we propose an alternate analysis of student responses from Watts’ interviews. In our analysis, we show how students’ activated resources about energy are disciplinarily productive. We suggest that fostering seeds of scientific understandings in students’ ideas about energy may play an important …