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Full-Text Articles in Physics
Precision And Accuracy Of Thermal Calibration Of Atomic Force Microscopy Cantilevers, Nancy Burnham, G Matei, E Thoreson, J Pratt, D Newell
Precision And Accuracy Of Thermal Calibration Of Atomic Force Microscopy Cantilevers, Nancy Burnham, G Matei, E Thoreson, J Pratt, D Newell
Nancy A. Burnham
To have confidence in force measurements made with atomic force microscopes(AFMs), the spring constant of the AFM cantilevers should be known with good precision and accuracy, a topic not yet thoroughly treated in the literature. In this study, we compared the stiffnesses of uncoated tipless uniform rectangular silicon cantilevers among thermal, loading, and geometric calibration methods; loading was done against an artifact from the National Institute of Standards and Technology (NIST). The artifact was calibrated at NIST using forces that were traceable to the International System of units. The precision and accuracy of the thermal method were found to be …
Velocity Imaging For The Liquid–Gas Interface In The Near Field Of An Atomizing Spray: Proof Of Concept, David L. Sedarsky, Megan E. Paciaroni, Mark A. Linne, James R. Gord, Terrence R. Meyer
Velocity Imaging For The Liquid–Gas Interface In The Near Field Of An Atomizing Spray: Proof Of Concept, David L. Sedarsky, Megan E. Paciaroni, Mark A. Linne, James R. Gord, Terrence R. Meyer
Terrence R Meyer
We describe adaptation of ballistic imaging for the liquid core of an atomizing spray. To describe unambiguously the forces that act to break apart the liquid core in a spray, one must directly measure the force vectors themselves. It would be invaluable, therefore, to obtain velocity and acceleration data at the liquid-gas interface. We employ double-image ballistic imaging to extract velocity information through the application of image analysis algorithms. This method is shown to be effective for liquid phase droplet features within the resolution limit of the imaging system. In light of these results, it is clear that a three- …
Substrate Rigidity Regulates The Formation And Maintenance Of Tissues, Nancy Burnham, Wei-Hui Guo, Margo Frey, Yu-Li Wang
Substrate Rigidity Regulates The Formation And Maintenance Of Tissues, Nancy Burnham, Wei-Hui Guo, Margo Frey, Yu-Li Wang
Nancy A. Burnham
The ability of cells to form tissues represents one of the most fundamental issues in biology. However, it is unclear what triggers cells to adhere to one another in tissues and to migrate once a piece of tissue is planted on culture surfaces. Using substrates of identical chemical composition but different flexibility, we show that this process is controlled by substrate rigidity: on stiff substrates, cells migrate away from one another and spread on surfaces, whereas on soft substrates they merge to form tissue-like structures. Similar behavior was observed not only with fibroblastic and epithelial cell lines but also explants …