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Articles 31 - 46 of 46
Full-Text Articles in Physics
In Vitro Analysis Of Immersed Human Tissues By Raman Microspectroscopy, Franck Bonnier, A. Mehmood, Peter Knief, Aidan Meade, Helen Lambkin, Kathleen Flynn, V. Mcdonagh, C. Healy, T. C. Lee, Fiona Lyng, Hugh Byrne
In Vitro Analysis Of Immersed Human Tissues By Raman Microspectroscopy, Franck Bonnier, A. Mehmood, Peter Knief, Aidan Meade, Helen Lambkin, Kathleen Flynn, V. Mcdonagh, C. Healy, T. C. Lee, Fiona Lyng, Hugh Byrne
Articles
Raman microspectroscopy is a powerful tool for the analysis of tissue sections, providing a molecular map of the investigated samples. Nevertheless, data pre-processing and, particularly, the removal of the broad background to the spectra remain problematic. Indeed, the physical origin of the background has not been satisfactorily determined. Using 785 nm as source in a confocal geometry, it is demonstrated for the example of the protein kappa-elastin that the background and resulting quality of the recorded spectrum are dependent on the morphology of the sample. Whereas a fine powder yields a dominant broad background, compressed pellets and solution-cast thin films …
Optical Cell For Combinatorial In Situ Raman Spectroscopic Measurements Of Hydrogen Storage Materials At High Pressures And Temperatures, Jason R. Hattrick-Simpers, Wilbur S. Hurst, Sesha S. Srinivasan, James E. Maslar
Optical Cell For Combinatorial In Situ Raman Spectroscopic Measurements Of Hydrogen Storage Materials At High Pressures And Temperatures, Jason R. Hattrick-Simpers, Wilbur S. Hurst, Sesha S. Srinivasan, James E. Maslar
Faculty Publications
An optical cell is described for high-throughput backscattering Raman spectroscopic measurements of hydrogen storagematerials at pressures up to 10 MPa and temperatures up to 823 K. High throughput is obtained by employing a 60 mm diameter × 9 mm thick sapphire window, with a corresponding 50 mm diameter unobstructed optical aperture. To reproducibly seal this relatively large window to the cell body at elevated temperatures and pressures, a gold o-ring is employed. The sample holder-to-window distance is adjustable, making this cell design compatible with optical measurement systems incorporating lenses of significantly different focal lengths, e.g., microscope objectives and single element …
Multiferroic Pb(Fe1/2Nb1/2)O3 Single Crystals: A Raman Scattering Study, A. F. García-Flores, Dmitri A. Tenne, W. J. Ren, X. X. Xi., S.-W. Cheong
Multiferroic Pb(Fe1/2Nb1/2)O3 Single Crystals: A Raman Scattering Study, A. F. García-Flores, Dmitri A. Tenne, W. J. Ren, X. X. Xi., S.-W. Cheong
Physics Faculty Publications and Presentations
No abstract provided.
A Raman Spectroscopy Study Of The Solubilisation Of Swcnts By Polycyclic Aromatic Hydrocarbons, Sourabhi Debnath, Qiaohuan Cheng, Theresa Hedderman, Hugh Byrne
A Raman Spectroscopy Study Of The Solubilisation Of Swcnts By Polycyclic Aromatic Hydrocarbons, Sourabhi Debnath, Qiaohuan Cheng, Theresa Hedderman, Hugh Byrne
Articles
The effectiveness of polycyclic aromatic hydrocarbons (PAHs) for selective solubilisation of single walled carbon nanotubes (SWCNTs) has been studied by Raman spectroscopy. Polyphenyl and polyacene PAHs of different lengths are used. Selective interaction between the PAHs and SWCNT is investigated by analyzing the Raman radial breathing modes the frequency positioning of which yields information concerning the diameter distribution of the SWCNT sample. Samples were dispersed at concentrations below the debundling limit and deposited on quartz substrates. A combination of four laser excitation energies was utilized to establish the distribution of diameters present. The results show that the PAHs interact with …
Structural Development In Ge-Rich Ge-S Glasses, Y. Sakaguchi, Dmitri Tenne, Maria Mitkova
Structural Development In Ge-Rich Ge-S Glasses, Y. Sakaguchi, Dmitri Tenne, Maria Mitkova
Physics Faculty Publications and Presentations
The Raman spectra of Ge-S glasses in the Ge-rich region from Ge 33 to 46 % have been investigated in order to know the structural development of the network glasses. From the detailed curve fits, we have found that there is an unassigned peak at 410 cm-1 and it becomes larger with increasing Ge composition. To clarify the structural origin of the peak, we virtually constructed the atomic arrangement of the glassy state starting from the crystalline state through the liquid state and changed the composition gradually depleting the medium in sulfur. From the consideration of the structural modeling …
Spectroscopic Investigations On Polypropylene-Carbon Nanofiber Composites: I. Raman And Electron Spin Resonance Spectroscopy, Mircea Chipara, John R. Villarreal, Magdalena Dorina Chipara, Karen Lozano, Alin Cristian Chipara, David J. Sellmyer
Spectroscopic Investigations On Polypropylene-Carbon Nanofiber Composites: I. Raman And Electron Spin Resonance Spectroscopy, Mircea Chipara, John R. Villarreal, Magdalena Dorina Chipara, Karen Lozano, Alin Cristian Chipara, David J. Sellmyer
David Sellmyer Publications
Isotactic polypropylene-vapor grown carbon nanofiber composites containing various fractions of carbon nanofibers, ranging from 0 to 20 wt %, have been prepared. Raman spectroscopy was used to analyze the effect of the dispersion of carbon nanofibers within polypropylene and the interactions between carbon nanofibers and macromolecular chains. The as-recorded Raman spectra have been successfully fitted by a linear convolution of Lorentzian lines. Changes of the Raman lines parameters (position, intensity, width, and area) of polypropylene and carbon nanofibers were analyzed in detail. The Raman spectra of the polymeric matrix—at low concentrations of nanofibers—show important modifications that indicate strong interactions between …
The Use Of Raman Spectroscopy In The Characterization Of Single Walled Carbon Nanotubes, Elizabeth Gregan
The Use Of Raman Spectroscopy In The Characterization Of Single Walled Carbon Nanotubes, Elizabeth Gregan
Doctoral
Carbon nanotubes, long, thin cylinders of carbon are intriguing structures and
have sparked much excitement in recent years. It is clear that understanding the fundamental properties of nanotubes is necessary to get a realisation of the full potential of these materials. Processing and purification on a mass scale will need to be carried out if these materials are to have large scale industrial applications and move beyond the laboratory bench. Highly sensitive, capital intensive equipment such as TEM and AFM, have been used to identify the state and morphology of tube samples as well as their levels of purity, however …
Growth Substrate Induced Functional Changes Elucidated By Ftir And Raman Spectroscopy In In-Vitro Cultured Human Keratinocytes., Aidan Meade, Fiona Lyng, Peter Knief, Hugh Byrne
Growth Substrate Induced Functional Changes Elucidated By Ftir And Raman Spectroscopy In In-Vitro Cultured Human Keratinocytes., Aidan Meade, Fiona Lyng, Peter Knief, Hugh Byrne
Articles
Non-invasive measurements of cellular function in in-vitro cultured cell lines using vibrational spectroscopy require the use of spectroscopic substrates such as quartz, ZnSe and MirrIR etc. These substrates are generally dissimilar to the original in-vivo extracellular environment of a given cell line and are often tolerated poorly by cultured cell lines resulting in morphological and functional changes in the cell. The present study demonstrates various correlations between vibrational spectroscopic analyses and biochemical analyses in the evaluation of the interaction of a normal human epithelial keratinocyte cell line (HaCaT) with MirrIR and quartz substrates coated with fibronectin, laminin and gelatin. The …
Femtosecond Nuclear Motion Of Hcl Probed By Resonant X-Ray Raman Scattering In The Cl 1s Region, Marc Simon, Loic Journel, Stephane Carniato, Richard Taieb, I. Minkov, Faris Gel'mukhanov, P. Salek, H. Agren, Renaud Guillemin, Wayne C. Stolte, A. C. Hudson, Dennis W. Lindle
Femtosecond Nuclear Motion Of Hcl Probed By Resonant X-Ray Raman Scattering In The Cl 1s Region, Marc Simon, Loic Journel, Stephane Carniato, Richard Taieb, I. Minkov, Faris Gel'mukhanov, P. Salek, H. Agren, Renaud Guillemin, Wayne C. Stolte, A. C. Hudson, Dennis W. Lindle
Chemistry and Biochemistry Faculty Research
Femtosecond dynamics are observed by resonant x-ray Raman scattering (RXS) after excitation along the dissociative Cl 1s→6ơ* resonance of gas-phase HCl. The short core-hole lifetime results in a complete breakdown of the common nondispersive behavior of soft-x-ray transitions between parallel potentials. We evidence a general phenomenon of RXS in the hard-x-ray region: a complete quenching of vibrational broadening. This opens up a unique opportunity for superhigh resolution x-ray spectroscopy beyond vibrational and lifetime limitations.
Potential Of Vibrational Spectroscopy In The Diagnosis Of Human Tumours., Eoghan O'Faolain
Potential Of Vibrational Spectroscopy In The Diagnosis Of Human Tumours., Eoghan O'Faolain
Doctoral
Just fewer than 20,000 people are annually diagnosed with some form of cancer in Ireland and one in three people are likely to contract some form of cancer by age 74. With the number of cases increasing at an annual rate of 2%, the early detection and treatment of cancer is becoming increasingly important. Both IR and Raman spectroscopy offer the potential for real time, quantitative detection of cancer and even precancer. This study investigates the potential of Raman and Fourier transform infrared, both benchtop and synchrotron spectroscopies for the detection of cervical cancer. The tissue was classified and its …
Correlation Of Spectroscopic And Biochemical Assays Postionising Radiation Exposure In Human Skin Cell Analogues, Aidan Meade, Hugh Byrne, Fiona Lyng
Correlation Of Spectroscopic And Biochemical Assays Postionising Radiation Exposure In Human Skin Cell Analogues, Aidan Meade, Hugh Byrne, Fiona Lyng
Conference papers
Raman spectroscopy, as an evaluation of the products of ionising radiation exposure in biological systems, has been utilised mainly in the evaluation of the impact of exposure in tissue, cellular constituents and live animals. It has also been recently demonstrated that Raman spectroscopy can demonstrate key spectroscopic changes in the live cell associated with significant apoptotic and necrotic chemical damage. The present preliminary work utilises Raman spectroscopy at 514.5 nm to evaluate the results of exposure to -rays in HaCaT cells from a Co-60 therapy source, in tandem with other biological assays. The results demonstrate that a number of spectral …
The Potential Of Vibrational Spectroscopy In The Early Detection Of Cervical Cancer: An Exciting Emerging Field, Eoghan O'Faolain, Mary Hunter, Joe Byrne, Peter Kelehan, Hugh Byrne, Fiona Lyng
The Potential Of Vibrational Spectroscopy In The Early Detection Of Cervical Cancer: An Exciting Emerging Field, Eoghan O'Faolain, Mary Hunter, Joe Byrne, Peter Kelehan, Hugh Byrne, Fiona Lyng
Conference papers
The application of vibrational spectroscopy to disease diagnosis is a relatively new, rapidly evolving scientific field. Techniques such as Raman and infrared spectroscopy have shown great promise in this regard over the past number of years. This study directly compared Raman spectroscopy and synchrotron infrared (SR-IR) spectroscopy on parallel cervical cancer samples. Both frozen and dewaxed formalin fixed paraffin preserved tissue sections were examined. Both tissue types produced good quality Raman and SR-IR spectra, although the lesser processed, frozen tissue sections displayed the most detailed spectra. Spectroscopy was shown capable of discriminating between different cell types in normal cervical tissue. …
High-Resolution Near-Field Raman Microscopy Of Single-Walled Carbon Nanotubes, Achim Hartschuh, X. Sunney Xie, Lukas Novotny, Erik J. Sánchez
High-Resolution Near-Field Raman Microscopy Of Single-Walled Carbon Nanotubes, Achim Hartschuh, X. Sunney Xie, Lukas Novotny, Erik J. Sánchez
Physics Faculty Publications and Presentations
We present near-field Raman spectroscopy and imaging of single isolated single-walled carbon nanotubes with a spatial resolution of approximately 25 nm. The near-field origin of the image contrast is confirmed by the measured dependence of the Raman scattering signal on tip-sample distance and the unique polarization properties. The method is used to study local variations in the Raman spectrum along a single single-walled carbon nanotube.
Raman Spectroscopic Study Of The Formation Of T-Mosi2 From Mo/Si Multilayers, Ming Cai, David D. Allred, A. Reyes-Mena
Raman Spectroscopic Study Of The Formation Of T-Mosi2 From Mo/Si Multilayers, Ming Cai, David D. Allred, A. Reyes-Mena
Faculty Publications
We have used Raman spectroscopy, large- and small-angle x-ray diffraction spectroscopy of sputter-deposited, vacuum-annealed, soft x-ray Mo/Si thin-film multilayers to study the physics of silicide formation. Two sets of multilayer samples with d-spacing 8.4 and 2.0 nm have been studied. Annealing at temperatures above 800 °C causes a gradual formation of amorphous MoSi2 interfaces between the Si and Mo layers. The transition from amorphous to crystalline MoSi2 is abrupt. The experimental results indicate that nucleation is the dominant process for the early stage and crystallization is the dominant process after nucleation is well advanced. In the thicker multilayer, a portion …
Use Of Raman Spectroscopy In Characterizing Soft X-Ray Multilayers: Tools In Understanding Structure And Interfaces, Ming Cai, Qi Wang, David D. Allred, Larry V. Knight, Dorian M. Hatch, A. Reyes-Mena, Guizhong Zhang
Use Of Raman Spectroscopy In Characterizing Soft X-Ray Multilayers: Tools In Understanding Structure And Interfaces, Ming Cai, Qi Wang, David D. Allred, Larry V. Knight, Dorian M. Hatch, A. Reyes-Mena, Guizhong Zhang
Faculty Publications
Our group is studying the structure and interfaces of soft x-ray multilayers by various techniques including x-ray diffraction and Raman spectroscopy. Raman spectroscopy is particularly useful since it is sensitive to the identity of individual bonds and thus can potentially characterize the abruptness of interfaces in multilayers. Blocking interfacial mixing is very important in achieving and maintaining high reflectivity. We report our studies of the as-deposited and postannealed structure of Mo/Si and W/C multilayers. The Mo/Si system is probably the most widely studied multilayer currently because of its potential applications for soft x-ray projection lithography for the range of 13 …
Characterization Of Metal/Carbon Multilayers By Raman Spectroscopy, David D. Allred, Qi Wang, Jesus González-Hernández
Characterization Of Metal/Carbon Multilayers By Raman Spectroscopy, David D. Allred, Qi Wang, Jesus González-Hernández
Faculty Publications
Laser Raman spectroscopy has been found to be useful for characterizing amorphous semiconductor multilayers, especially the interfaces of multilayers. Recently, we have extended this technique to the characterization of magnetron sputtered multilayers commonly used as reflectors in soft x-ray optics. Unlike the multilayers previously studied which contained only semiconductors and dielectrics, these are generally semiconductor/metal multilayers. We report here on the Raman characterization of the most common class of multilayers used in soft x-ray optics, those that contain a high density metal like tungsten interspersed with layers of carbon. In all of the metal/carbon multilayers the dominate feature in the …