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Articles 31 - 34 of 34
Full-Text Articles in Physics
Label-Free Raman Imaging To Monitor Breast Tumor Signatures, John Ciubuc
Label-Free Raman Imaging To Monitor Breast Tumor Signatures, John Ciubuc
Open Access Theses & Dissertations
Methods built on Raman spectroscopy have shown major potential in describing and discriminating between malignant and benign specimens. Accurate, real-time medical diagnosis benefits in substantial improvements through this vibrational optical method. Not only is acquisition of data possible in milliseconds and analysis in minutes, Raman allows concurrent detection and monitoring of all biological components. Besides validating a significant Raman signature distinction between non-tumorigenic (MCF-10A) and tumorigenic (MCF-7) breast epithelial cells, this study reveals a label-free method to assess overexpression of epidermal growth factor receptors (EGFR) in tumor cells. EGFR overexpression sires Raman features associated with phosphorylated threonine and serine, and …
Enhanced Ablation By Femtosecond And Nanoseond Pulses, Haley Kerrigan
Enhanced Ablation By Femtosecond And Nanoseond Pulses, Haley Kerrigan
Electronic Theses and Dissertations
Laser ablation of GaAs by a combination of femtosecond and nanosecond pulses is investigated as a means of enhancing material removal by a femtosecond pulse in the filamentation intensity regime. We demonstrate for the first time increased ablation of GaAs by ultrafast laser pulse plasmas augmented by nanosecond pulse radiation from a secondary laser. Material removal during laser ablation is a complex process that occurs via multiple mechanisms over several timescales. Due to different pulse durations, ablation by femtosecond and nanosecond pulses are dominated by different mechanisms. Ablation can be enhanced by optimally combining a femtosecond and nanosecond pulse in …
Filament Wavefront Evolution, Daniel Thul
Filament Wavefront Evolution, Daniel Thul
Electronic Theses and Dissertations
Filamentation is a complex process that gives rise to many nonlinear interactions. However, the fundamentals of filament formation and propagation can be explained in terms of two dominant mechanisms: Kerr self-focusing and plasma defocusing. The first to occur, self-focusing, is responsible for an increase in irradiance through beam collapse. This process requires sufficient initial peak power, on the order of gigawatts for near infrared beams in air. Plasma defocusing then arrests the collapse process once the irradiance reaches the ionization threshold of the medium. These two processes balance each other in an extended plasma channel known as a filament. A …
Simulation Of Magnetically Confined Inductively Coupled Plasma, Sina Javadpour
Simulation Of Magnetically Confined Inductively Coupled Plasma, Sina Javadpour
Electronic Theses and Dissertations
In this work, a new parallel coil design was presented to address the need for high density inductively coupled plasmas with enhanced properties and a more uniform and consistent distribution, suitable for large-area material processing. Fluid model simulations of 3D argon inductively coupled plasma (ICP) were performed in COMSOL for the proposed coil and a conventional single cylindrical coil with the same impedance to be used as reference, to compare and evaluate the performance of this new halftoroidal parallel coil design and study its effects on the main variables of the generated plasma. Through different comparisons of the simulations results, …