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Macular Pigment Response To A Supplement Containing Meso-Zeaxanthin, Lutein And Zeaxanthin, Richard A. Bone, John T. Landrum, Yisi Cao, Alan N. Howard, Francesca Alvarez-Calderon
Macular Pigment Response To A Supplement Containing Meso-Zeaxanthin, Lutein And Zeaxanthin, Richard A. Bone, John T. Landrum, Yisi Cao, Alan N. Howard, Francesca Alvarez-Calderon
Department of Physics
Background: Age-related macular degeneration (AMD) is a disease with multiple risk factors, many of which appear to involve oxidative stress. Macular pigment, with its antioxidant and lightscreening properties, is thought to be protective against AMD. A result has been the appearance of dietary supplements containing the macular carotenoids, lutein and zeaxanthin. More recently, a supplement has been marketed containing, in addition, the third major carotenoid of the macular pigment, meso-zeaxanthin. The purpose of the study was to determine the effectiveness of such a supplement in raising macular pigment density in human subjects. Methods: A 120 day supplementation study was conducted …