Theory and Algorithms Commons^™

Exploration Of Feature Selection Techniques In Machine Learning Models On Hptlc Images For Rule Extraction, Bozidar-Brannan Kovachev

Honors Theses

Research related to Biology often utilizes machine learning models that are ultimately uninterpretable by the researcher. It would be helpful if researchers could leverage the same computing power but instead gain specific insight into decision-making to gain a deeper understanding of their domain knowledge. This paper seeks to select features and derive rules from a machine learning classification problem in biochemistry. The specific point of interest is five species of Glycyrrhiza, or Licorice, and the ability to classify them using High-Performance Thin Layer Chromatography (HPTLC) images. These images were taken using HPTLC methods under varying conditions to provide eight …