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Full-Text Articles in Radiochemistry
Assessment Of Mucin 13 (Muc13) As An Imaging Target For Guiding Colorectal Cancer Treatment: A Pathway Towards Theranostic Development, Ryan P. Coll, Aiko Yamaguchi, Jianbo Wang, Xiaoxia Wen, Denise Hernandez, Subhash C. Chauhan, H. Charles Manning
Assessment Of Mucin 13 (Muc13) As An Imaging Target For Guiding Colorectal Cancer Treatment: A Pathway Towards Theranostic Development, Ryan P. Coll, Aiko Yamaguchi, Jianbo Wang, Xiaoxia Wen, Denise Hernandez, Subhash C. Chauhan, H. Charles Manning
Research Symposium
Background: A theranostic strategy combining diagnostic imaging and targeted therapy in a single regimen is proposed for improved management and treatment of colorectal cancer (CRC). Increased specificity in detection by the noninvasive imaging technique positron emission tomography (PET) can be achieved by radiolabeling antibodies (Abs) designed to target tumor-associated antigens with increased expression post-translational modifications present in cancer cells. In this study, an Ab designed to target the transmembrane glycoprotein mucin 13 (MUC13) was radiolabeled with the positron-emitting radionuclide zirconium-89 (89Zr) for PET imaging of a xenograft mouse model of CRC. Specified uptake of this radioimmunoconjugate was observed …
Undergraduate Research Opportunities Program 2010, University Of Nevada, Las Vegas
Undergraduate Research Opportunities Program 2010, University Of Nevada, Las Vegas
Undergraduate Research Opportunities Program (UROP)
The Undergraduate Research Opportunities Program (UROP) cultivates and supports research partnerships and invites undergraduates to work as the junior colleagues of faculty. The program offers the opportunity to work on cutting edge research—whether you join established research projects or pursue your own ideas. As participants, undergraduates engage in each phase of standard research activity: developing research plans, writing proposals, conducting research, analyzing data. and presenting research results in oral and written form. The projects take place over the summer, and research can be done in any academic department or interdisciplinary laboratory. Projects can last for an entire semester, and many …
Undergraduate Research Opportunities Program, University Of Nevada Las Vegas, College Of Sciences
Undergraduate Research Opportunities Program, University Of Nevada Las Vegas, College Of Sciences
Undergraduate Research Opportunities Program (UROP)
No abstract provided.