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Articles 1 - 2 of 2
Full-Text Articles in Polymer Chemistry
Understanding The Functional Group-Dependent Self-Assembly And Cellular Entry Of Cationic Conjugated Polymer Nanoparticles, Prakash Manandhar
Understanding The Functional Group-Dependent Self-Assembly And Cellular Entry Of Cationic Conjugated Polymer Nanoparticles, Prakash Manandhar
FIU Electronic Theses and Dissertations
Highly fluorescent conjugated polymers (CPs) are an important class of biomaterials used for various biological applications including labelling, sensing, and delivery of biological substances. Synthetic versatility and tunable emission make CPs a superior class of biomaterials. Understanding the structure-function relationship of CPs plays a vital role in designing high performing biomaterials. The cationic CPs are self-assembled to conjugated polymer nanoparticles (CPNs) in an aqueous environment due to their amphiphilicity. The physical and biophysical properties of CPNs are highly dependent on the chemical functionality and backbone structure of CPs. Modulation of the surface property and backbone structure of CPNs play an …
Conjugated Polymer-Based Biomaterials Through Controlled Self-Assembly, Megan Twomey
Conjugated Polymer-Based Biomaterials Through Controlled Self-Assembly, Megan Twomey
FIU Electronic Theses and Dissertations
Synthetic polymeric materials have gained significant use as biological materials (biomaterials) in biomedical and pharmaceutical applications. As a result, a demand for well-defined polymers with tunable properties has emerged. The synthetic versatility of polymeric biomaterials allows the opportunity to understand the structure-property relationship of materials and their cellular interactions. A novel class of polymeric biomaterials are conjugated polymers (CPs), which possess desirable physicochemical and excellent photophysical properties, including inherent fluorescence. The synthetic versatility of CPs allows easy modification of the conjugated backbone to tune emission and side chain structures to adjust biocompatibility through increased water solubility, controlled biodegradability, and incorporation …