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Physical Chemistry Commons

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SUNY Geneseo

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Full-Text Articles in Physical Chemistry

062— Nano-Size Dependence In Aggregation Process Of Beta 2 Microglobulin Coated Gold Colloids, Kaylee A. Hausrath Apr 2021

062— Nano-Size Dependence In Aggregation Process Of Beta 2 Microglobulin Coated Gold Colloids, Kaylee A. Hausrath

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The formation of the aggregates of the beta 2 microglobulin (b2m) coated nano-gold colloids were investigated for various nanogold colloid sizes ranging between 10 nm and 100 nm. The aggregation process was considered to be initiated by the selfassembly of b2m by transforming the folded to the unfolded structure under highly acidic condition (pH < 4). The formation of the aggregates were monitored by a peak shift of surface plasmon resonance (SPR) band as a function of number of free b2m available. As for relatively smaller size of gold colloid diameter a gradual aggregation process was observed. The size of the aggregates was considered to increase monotonically as the b2m was added. On the other hand, as for relatively larger diameter of gold colloid, stepwise aggregation process was observed. So that the aggregates of a particular size was formed at a certain threshold of the concentration of available free b2m. The majority of the gold surface of the smaller gold size was easily covered and support the aggregation even at the lower concentration of b2m.


354— Observation Of Acid Penetration Of Nano-Gold Doped Sol-Gel System, Mir Ali, Eric Koessler Apr 2020

354— Observation Of Acid Penetration Of Nano-Gold Doped Sol-Gel System, Mir Ali, Eric Koessler

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The penetration of the acid into gold doped sol-gel material was measured. The acid penetration speed increased as the nano size increased up from 5 nm to 20 nm. Then there was almost no penetration at 60 nm. The nano dependent rate change was complex and needs to be investigated further. Also, recent new methodology to create the gel showed a significance stability and it took more than a few days to complete the penetration.