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Full-Text Articles in Inorganic Chemistry
Purification And Activity Analysis Of A Highly Active Recombinant Catalase From Psychrophilic Bacterium Psychrobacter Cryohaloentis, Andrew Stewart
Purification And Activity Analysis Of A Highly Active Recombinant Catalase From Psychrophilic Bacterium Psychrobacter Cryohaloentis, Andrew Stewart
Honors Program Theses
To date, the genus Psychrobacter includes 37 recognized bacterial species isolated from different sources ranging from Siberian permafrost (P. cryohalolentis) to seal feces (P. lutiphocae). Due to its diverse ecological niches, several species belonging to the genus have different enzymatic activities with potential applications in bioremediation and the food industry. In this study, a bioprospecting approach was used to perform a in depth analysis of a Psychrobacter-like bacterial strain isolated from goose feces (designated as Psychrobacter unknown). The phylogenetic analysis of 16S rRNA gene and homologous sequence studies suggest that the strain may represent a novel species of the Psychrobacter …
Synthesis Of A Series Of Ag(I)-Nhc Complexes For Future Antibacterial Studies, Alyssa Malto
Synthesis Of A Series Of Ag(I)-Nhc Complexes For Future Antibacterial Studies, Alyssa Malto
Honors Program Theses
For thousands of years, silver (Ag) has been widely used for medicinal purposes due to its broad-spectrum antimicrobial properties. While medicinal silver usage declined with the advent of antibiotics, there has been a renewed interest in therapeutic silver coordination compounds to combat the spread of antibiotic resistance. N-heterocyclic carbenes (NHCs) are promising ligands for silver metallodrugs due to their wide structural variety that allows for tunability of the complex’s overall steric and electronic properties and previously established bioactivity against various pathogens and cancer cell lines. There is potential for efficacy against biofilms, a type of microbial growth pattern that is …