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An Innovative "Green" Suzuki Coupling Reaction For The Crl-232 Lab, James W. Wheeler, David Dehm
An Innovative "Green" Suzuki Coupling Reaction For The Crl-232 Lab, James W. Wheeler, David Dehm
Chemistry Student Work
A major objective of “Green Chemistry” is to provide a more modern chemical experience in the laboratory along with reducing the amount of waste generated and make the lab safer for our students. The latest effort is the continuance to update the chemical reactions in the DHE 232 Organic Chemistry Lab by employing a “water-based” Suzuki Coupling Reaction. The 2010 Nobel prize was awarded to Heck, Negishi, and Suzuki for the palladium-catalyzed cross coupling reaction. This reaction has gained wide acceptance in industry where it is used in large scale reactions to make drugs (naproxen, 5-HT1a Agonist), agricultural chemicals (Boscalid® …