Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Arkansas, Fayetteville (12)
- Western University (9)
- City University of New York (CUNY) (8)
- The University of Southern Mississippi (7)
- Selected Works (6)
-
- University of Kentucky (6)
- University of South Florida (6)
- East Tennessee State University (5)
- Florida International University (5)
- University of Massachusetts Amherst (5)
- University of Nebraska - Lincoln (5)
- University of Tennessee, Knoxville (5)
- Wayne State University (5)
- Old Dominion University (4)
- Colby College (3)
- James Madison University (3)
- University of Missouri, St. Louis (3)
- Butler University (2)
- California Polytechnic State University, San Luis Obispo (2)
- Chapman University (2)
- DePaul University (2)
- Georgia State University (2)
- Kennesaw State University (2)
- Marquette University (2)
- Murray State University (2)
- Parkland College (2)
- Rowan University (2)
- Tennessee State University (2)
- University at Albany, State University of New York (2)
- University of Denver (2)
- Keyword
-
- Synthesis (10)
- Pure sciences (8)
- Self-assembly (5)
- Annulation (3)
- Antibiotics (3)
-
- Aromaticity (3)
- Catalysis (3)
- Chemistry (3)
- Cycloaddition (3)
- Diazonium (3)
- Medicinal chemistry (3)
- Nafion (3)
- Organic chemistry (3)
- Photochemistry (3)
- Stimuli responsive (3)
- Total synthesis (3)
- Asymmetric synthesis (2)
- Carbene (2)
- Catalyst (2)
- Characterization (2)
- Chemistry and Biochemistry (2)
- Click chemistry (2)
- Heterocycle (2)
- Indole (2)
- Ionic liquids (2)
- Kinetics (2)
- Metabolomics (2)
- Nanoparticle (2)
- Organic synthesis (2)
- PET (2)
- Publication
-
- Electronic Theses and Dissertations (8)
- Electronic Thesis and Dissertation Repository (8)
- Graduate Theses and Dissertations (8)
- Doctoral Dissertations (6)
- USF Tampa Graduate Theses and Dissertations (6)
-
- Dissertations, Theses, and Capstone Projects (5)
- FIU Electronic Theses and Dissertations (5)
- Honors Theses (5)
- Theses and Dissertations (5)
- Chemistry & Biochemistry Faculty Works (4)
- Chemistry Faculty Publications (4)
- Department of Chemistry: Dissertations, Theses, and Student Research (4)
- Dissertations (4)
- Masters Theses (4)
- Wayne State University Dissertations (4)
- Senior Honors Projects, 2010-2019 (3)
- Biology, Chemistry, and Environmental Sciences Faculty Articles and Research (2)
- Chemistry & Biochemistry Faculty Publications (2)
- Chemistry & Biochemistry Theses & Dissertations (2)
- Chemistry & Biochemistry Undergraduate Honors Theses (2)
- Chemistry Faculty Research (2)
- DePaul Discoveries (2)
- Georgia State Undergraduate Research Conference (2)
- Journal of the Arkansas Academy of Science (2)
- Legacy Theses & Dissertations (2009 - 2024) (2)
- Master's Theses (2)
- Masters Theses & Specialist Projects (2)
- Matthew F Rouhier (2)
- Natural Sciences Student Research Presentations (2)
- Open Access Theses & Dissertations (2)
Articles 151 - 155 of 155
Full-Text Articles in Chemistry
Probing Allosteric, Partial Inhibition Of Thrombin Using Novel Anticoagulants, Stephen S. Verespy Iii
Probing Allosteric, Partial Inhibition Of Thrombin Using Novel Anticoagulants, Stephen S. Verespy Iii
Theses and Dissertations
Thrombin is the key protease that regulates hemostasis; the delicate balance between procoagulation and anticoagulation of blood. In clotting disorders, like deep vein thrombosis or pulmonary embolism, procoagulation is up-regulated, but propagation of clotting can be inhibited with drugs targeting the proteases involved, like thrombin. Such drugs however, have serious side effects (e.g., excessive bleeding) and some require monitoring during the course of treatment. The reason for these side effects is the mechanism by which the drugs’ act. The two major mechanisms are direct orthosteric and indirect allosteric inhibition, which will completely abolish the protease’s activity. Herein we sought an …
The Development Of Colorimetric Assays To Determine The Identity And Frequency Of Specific Nucleobases In Dna Oligomers, Elizabeth Marie Thomas
The Development Of Colorimetric Assays To Determine The Identity And Frequency Of Specific Nucleobases In Dna Oligomers, Elizabeth Marie Thomas
Theses and Dissertations--Chemistry
Colorimetric methods combined with color-changing chemical probes are widely used as simple yet effective tools for identifying and quantifying a wide variety of molecules in solution. For nucleic acids (DNA and RNA), perhaps the most commonly used colorimetric probe is potassium permanganate, which can be used to identify single-stranded pyrimidines (thymine and cytosine) in polymers. Unfortunately, permanganate is not an effective probe for identifying purines (adenine and guanine), especially in the presence of the more reactive pyrimidines. Therefore, robust methods for discriminating between the purines remain elusive, thereby creating a barrier toward developing more complex colorimetric applications. In this dissertation, …
Organometallic Materials: Ferroceno[C]Thiophenes And 1,2-Bisthienylmetallocenes, Surya R. Banks
Organometallic Materials: Ferroceno[C]Thiophenes And 1,2-Bisthienylmetallocenes, Surya R. Banks
Theses and Dissertations--Chemistry
Development of synthetic routes toward two general organometallic frameworks was undertaken. The first project involved synthetic attempts of substituted and unsubstituted ferroceno[c]thiophene while the second one was the synthesis of 1,2-dithienylmetallocenes. The long-term goal of this work is to lay the foundations for study of electronic, electrochromic, redox, and optical properties of thiophene-based materials integrated with organometallic systems such as ferrocene, ruthenocene and cymantrene. The synthetic pathway for the target molecule in the first project involved converting 1,2-bis(hydroxymethyl)ferrocene to 1,2-bis(thiouroniummethyl)ferrocene with thiourea under acidic conditions. Refluxing the salt in base followed by acidification resulted in 1,2-bis(mercaptomethyl)ferrocene, which is …
Quantitative Model For Rationalizing Solvent Effect In Noncovalent Ch-Aryl Interactions, Bright C. Emenike, Sara N. Bey, Brianna C. Bigelow, Srinivas V.S. Chakravartula
Quantitative Model For Rationalizing Solvent Effect In Noncovalent Ch-Aryl Interactions, Bright C. Emenike, Sara N. Bey, Brianna C. Bigelow, Srinivas V.S. Chakravartula
Publications and Research
The strength of CH–aryl interactions (ΔG) in 14 solvents was determined via the conformational analysis of a molecular torsion balance. The molecular balance adopted folded and unfolded conformers in which the ratio of the conformers in solution provided a quantitative measure of ΔG as a function of solvation. While a single empirical solvent parameter based on solvent polarity failed to explain solvent effect in the molecular balance, it is shown that these ΔG values can be correlated through a multiparameter linear solvation energy relationship (LSER) using the equation introduced by Kamlet and Taft. The resulting LSER …
Interrogating Metabolism In Brain Cancer, Travis Salzillo, Jingzhe Hu, Linda Nguyen, Nicholas Whiting, Jaehyuk Lee, Joseph Weygand, Prasanta Dutta, Shivanand Pudakalakatti, Niki Zacharias Millward, Seth Gammon, Frederick F. Lang, Amy B. Heimberger, Pratip Bhattacharya