Chemistry Commons^™

Study Of Solvent-Free, Microwave-Assisted Ring-Opening Reactions Of Phenyl Glycidyl Ether With Azoles, Marygrace Mcafee, Joshua Pack, Brian Walker

Arkansas Women in STEM Conference

Literature precedent supports that microwave-assisted organic synthesis can afford fast, high-yield, and efficient synthetic pathways, often comparable to or better than traditional heating methods. Building on this, our work utilizes microwave-assisted synthesis for the epoxide ring opening of phenyl glycidyl ether through nucleophilic addition, aiming to create both pyrazole and imidazole derivatives. These heterocyclic azole compounds have been shown to be important due to their presence in many natural products, as well as their anti-fungal and other pharmacological activities. We are exploring the use of microwave irradiation under neat (solvent-free) conditions, focused on a streamlined approach to minimize time, energy …

Physiochemical Properties Of Urethane-Containing Ionic Liquids And Ionenes From A Non-Isocyanate Synthetic Approach, George Timmermann

Scholars Week

Ionic polymers that are designed to contain ionic liquids (ILs) in their backbones have been shown to exhibit a high degree of variability through changing the type of ionic character and the location of the ionic region within the molecule. This large amount of variability in both the structure and characteristics of ILs allows researchers to design task-specific ionic polymers and ILs for a variety of applications including gas separation membranes and solid polymer electrolytes. The synthesis of a specific class of ILs and ionenes through the incorporation of urethane groups with imidazolium rings by reacting carbonyl diimidazole with various …

Raising Global Awareness And Internationality In The Undergraduate Organic Chemistry Laboratory, Marissa Scilley, Michael R. Korn

Liberty University Research Week

Undergraduate

Applied

Synthesis Of Phosphindolizine, Tyler Bell

Campus Research Day

Synthesis of Phosphindolizine which hasn't been done before.

Greening Of Ferrocene Column Chromatography, Marissa Scilley, Anderson Hill, Michael R. Korn

Liberty University Research Week

Undergraduate

Basic

Incorporating The Origin Of Life Theme In Organic Chemistry Laboratories: Analyses Of Amino Acids, Emmalyn Sarver, Michael R. Korn

Liberty University Research Week

Undergraduate

Basic

Synthesis Of Dibenzophosphole Derivatives, Allan Roy Sison

Campus Research Day

This presentation will demonstrate how dibenzophosphole derivatives are synthesized. There will also be studies on the properties of this complex compound. Our experiment is based on previous studies on dibenzophospholes. We will be using the methods from the previous studies and we will synthesize the derivatives of the dibenzophosphole compound using other compounds such as dibromophenol.

"What Lights Up Your "Tech"? - Subtitle: Synthesis Of Polycyclic Aromatic Hydrocarbons (Pah) Using To 2,2-Dibromo-1,1-Binapthalene, Jefferd Daniel

Campus Research Day

The application of this molecule can be used eventually to add several elements like (Bromine, Chlorine, etc.) Previous done research that was conducted was in shortening the process to synthesize PAH. Since then, there has been research conducted to stabilize the compound by closing/linking two of the un-linked benzene rings.

Synthesize phosphyl-paralene, functionalize, and analyze the properties of those molecules and attach its derivatives

Synthesis Of Dibenzophospholes From Biphenyl, Claudia Velasquez

Campus Research Day

The aim is a direct synthesis of various diphenzylphospholes using biphenyl, phosphonic acid, and Tf2O. Successful addition of the phosphonic acid in a one step reaction would result in a more efficient production of the diphenylphospholes.

Opening Of An Epoxide Ring Using Azide To Form A Triazole, Emily Hufnagel, Jeffrey A. Hansen

Annual Student Research Poster Session

No abstract provided.

Synthesis Of Ether Alcohols With Varying Catalysts, Hannah Grady, Frida Li, Jeffrey A. Hansen

Annual Student Research Poster Session

No abstract provided.

Synthesis Of Cyclopropyl Analogs Of Acetylcholine, Douglas Armstrong, Zachary Emptage

Scholar Week 2016 - present

The Ph.D. research by Douglas Armstrong was highly successful for the synthesis of the trans cyclopropyl analog of acetylcholine, but only marginally successful for the cis isomer. In recent years he has developed novel ideas as to how the synthesis of the cis isomer may be improved upon, in ways using more current methods. He has done experiments using some of those methods, and the results, although preliminary, look good.

Synthesis Of A Sulfur Variant For Treatment Of Trypanosomiasis, Carlos Vera-Esquivel

UNO Student Research and Creative Activity Fair

Previous work in our lab has found diphenyl ether benzylamines showed a successful response with a micromolar concentration of our lead compound to treat the deadly Trypanosamiosis rhodesience. Furthermore, mammalian cell lines saw promising resistance towards damages. The goal of this study was to synthesize a diphenyl thio benzylamine variant. This variant was more active toward T. b. rhodesience but showed more toxicity to both rat 10 (IC₅₀ mM) and human cell lines (HFF, HC-₀₄, U-₂ OS, and HEK₂₉₃). The selectivity index (ratio of toxicity to activity in the same concentration units (SI)) …

An In Vitro Study On Skin Protection Across The Uv Spectra, Cheyenne Boone

Posters-at-the-Capitol

Skin cancer is the number one cancer in the United States. Lack of awareness of how harmful UV radiation is could be the cause of the over two million cases reported since 2012. It appears that there is not a lot information on the active ingredients used in sunscreens. Some of the compounds have been linked to birth defects, hormone disruptions, and the bleaching of coral reefs. Samples of commonly used sunscreens (both sprays and creams), cosmetic foundation, essential oils, lotions, and three pure organic actives were tested at specific concentrations and ran through a UV spectrometer. The results have …

New Reactions Of Strained Allyl Silacycles, Elizabeth Cummins

Graduate Student Symposium

Ring-strained allylsilanes exhibit both electrophilic and nucleophilic characteristics, allowing for simultaneous activation and allylation of carbonyl compounds. Results are presented describing an optimized synthesis of certain allylsilacyclobutanes and their use in several selective carbon-carbon bond forming reactions.

Tunable Copper Complexes For Sustainable Photocatalysis, David Kline

Posters-at-the-Capitol

Photoredox catalysis has direct applications in sustainable chemistry and thus an immense impact on our environment. With the ability to harness energy directly from the sun to catalyze useful chemical reactions, photocatalysts can help to eliminate the need for harsh reaction conditions and reduce generation of hazardous chemical waste. Photocatalysts based on Earth-abundant metals such as copper have recently emerged as sustainable alternatives to rare-earth metals including iridium and ruthenium, which are no longer required for many photocatalyzed chemical transformations.

Optimizing Synthesis Of Substituted Oxadiazole Based Liquid Crystal Compounds.Pptx, Blake Bordokas

Blake Bordokas

Spectrofluorometric Analysis Of Bisphenol-A In Drinking Water Bottles, Jeff Brochetti

Student Scholar Showcase

Spectrofluorometric Analysis of Bisphenol-A in Drinking Water Bottles

Bisphenol-A (BPA) is of environmental concern due to its ability to act as an endocrine disruptor in humans and many other animals. In the food industry, BPA is widely used in the production of plastic bottles and plastic liners in aluminum cans. Over time, trace amounts of BPA can leach from the container and into the contents inside. A new method of testing for trace amount of BPA involved the formation of an inclusion complex with ß-Cyclodextrin. With the formation of the inclusion complex, it becomes much easier to analyze low concentrations …