Ordinary Differential Equations and Applied Dynamics Commons^™

On Evolution Dynamics And Strategies In Some Host-Parasite Models, Liman Dai

Electronic Thesis and Dissertation Repository

In this thesis, we use mathematical models to study the problems about the evolution of hosts and parasites. Firstly, we study a within-host age-structured model with mutation and back mutation which is in the form of partial differential equations with double-infections by two strains of viruses. For the case when the production rates of viruses are gamma distributions, the PDE model can be transferred into an ODE one. Then, we analyze our model in two cases: one is without mutation, and the other is with mutation. In the first case, we prove that the two strains of viruses without mutation …

Modeling Leafhopper Populations And Their Role In Transmitting Plant Diseases., Ji Ruan

Electronic Thesis and Dissertation Repository

This M.Sc. thesis focuses on the interactions between crops and leafhoppers.

Firstly, a general delay differential equations system is proposed, based on the infection age structure, to investigate disease dynamics when disease latencies are considered. To further the understanding on the subject, a specific model is then introduced. The basic reproduction numbers $\cR_0$ and $\cR_1$ are identified and their threshold properties are discussed. When $\cR_0 < 1$, the insect-free equilibrium is globally asymptotically stable. When $\cR_0 > 1$ and $\cR_1 < 1$, the disease-free equilibrium exists and is locally asymptotically stable. When $\cR_1>1$, the disease will persist.

Secondly, we derive another general delay differential equations system to examine how different life stages of leafhoppers affect crops. The basic reproduction numbers $\cR_0$ is determined: when …

Eradicating Malaria: Improving A Multiple-Timestep Optimization Model Of Malarial Intervention Policy, Taryn M. Ohashi

Scripps Senior Theses

Malaria is a preventable and treatable blood-borne disease whose complications can be fatal. Although many interventions exist in order to reduce the impacts of malaria, the optimal method of distributing these interventions in a geographical area with limited resources must be determined. This thesis refines a model that uses an integer linear program and a compartmental model of epidemiology called an SIR model of ordinary differential equations. The objective of the model is to find an intervention strategy over multiple time steps and multiple geographic regions that minimizes the number of days people spend infected with malaria. In this paper, …

A Comparison And Catalog Of Intrinsic Tumor Growth Models, Elizabeth A. Sarapata

HMC Senior Theses

Determining the dynamics and parameter values that drive tumor growth is of great interest to mathematical modelers, experimentalists and practitioners alike. We provide a basis on which to estimate the growth dynamics of ten different tumors by fitting growth parameters to at least five sets of published experimental data per type of tumor. These timescale tumor growth data are also used to determine which of the most common tumor growth models (exponential, power law, logistic, Gompertz, or von Bertalanffy) provides the best fit for each type of tumor. In order to compute the best-fit parameters, we implemented a hybrid local-global …

Modeling The Genetic Consequences Of Mutualism On Communities, Carrie E. Eaton

Doctoral Dissertations

Three models of coevolutionary dynamics between mutualistically interacting species are developed. The first is a three loci, haploid model describing a general plant-pollinator system, such as Greya moth and its host plant. In this case, the system will always collapse to a single plant type and pollinator type. In a community with an mutant plant type, it is possible for a host-switch to occur, governed by the initial relative abundance plant type and the pollinator choosiness. In addition, genetic diversity can be maintained if the pollinator has no differential host preference, only adaptation to a host. Next, this model is …

A Study Of Nonlinear Dynamics In Mathematical Biology, Joseph Ferrara

UNF Graduate Theses and Dissertations

We first discuss some fundamental results such as equilibria, linearization, and stability of nonlinear dynamical systems arising in mathematical modeling. Next we study the dynamics in planar systems such as limit cycles, the Poincaré-Bendixson theorem, and some of its useful consequences. We then study the interaction between two and three different cell populations, and perform stability and bifurcation analysis on the systems. We also analyze the impact of immunotherapy on the tumor cell population numerically.