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Ordinary Differential Equations and Applied Dynamics Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Ordinary Differential Equations and Applied Dynamics
Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen
Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen
Theses and Dissertations (Comprehensive)
The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …
High-Order Relaxed Multirate Infinitesimal Step Methods For Multiphysics Applications, Jean Sexton
High-Order Relaxed Multirate Infinitesimal Step Methods For Multiphysics Applications, Jean Sexton
Mathematics Theses and Dissertations
In this work, we consider numerical methods for integrating multirate ordinary differential equations. We are interested in the development of new multirate methods with good stability properties and improved efficiency over existing methods. We discuss the development of multirate methods, particularly focusing on those that are based on Runge-Kutta theory. We introduce the theory of Generalized Additive Runge-Kutta methods proposed by Sandu and Günther. We also introduce the theory of Recursive Flux Splitting Multirate Methods with Sub-cycling described by Schlegel, as well as the Multirate Infinitesimal Step methods this work is based on. We propose a generic structure called Flexible …
Epistasis In Predator-Prey Relationships, Iuliia Inozemtseva
Epistasis In Predator-Prey Relationships, Iuliia Inozemtseva
Electronic Theses and Dissertations
Epistasis is the interaction between two or more genes to control a single phenotype. We model epistasis of the prey in a two-locus two-allele problem in a basic predator- prey relationship. The resulting model allows us to examine both population sizes as well as genotypic and phenotypic frequencies. In the context of several numerical examples, we show that if epistasis results in an undesirable or desirable phenotype in the prey by making the particular genotype more or less susceptible to the predator or dangerous to the predator, elimination of undesirable phenotypes and then genotypes occurs.