Physical Sciences and Mathematics Commons^™

Me3al-Mediated Domino Nucleophilic Addition/Intramolecular Cyclisation Of 2-(2-Oxo-2-Phenylethyl)Benzonitriles With Amines; A Convenient Approach For The Synthesis Of Substituted 1-Aminoisoquinolines, Krishna M. S. Adusumalli, Lakshmi N.S. Konidena, Hima B. Gandham, Krishnaiah Kumari, Krishan R. Valluru, Satya K.R. Nidasanametla, Venkateswara R. Battula, Hari K. Namballa

Publications and Research

A simple and efficient protocol for the construction of 1-aminoisoquinolines was achieved by treating 2-(2-oxo-2- phenylethyl)benzonitriles with amines in the presence of Me 3 Al. The reaction proceeds via a domino nucleophilic addition with subsequent intramolecular cyclisation. This method provides a wide variety of substituted 1-aminoisoquinolines with good func- tional group tolerance. Furthermore, the synthetic utility of this protocol was demonstrated in the successful synthesis of the anti- tumor agent CWJ-a-5 in gram scale.

Advances In Rhizobial Research – Progress Priorities In Temperate Areas, Angela Sessitsch

IGC Proceedings (1993-2023)

Rhizobia are well known for their capacity to establish a symbiosis with legumes. During this symbiosis the bacteria inhabit root nodules where they reduce atmospheric nitrogen and make it available to the plant. Biological nitrogen fixation (BNF) is an important source of nitrogen and the various legume crops and pasture species often fix as much as 200-300 kg nitrogen per hectare (Peoples et al., 1995). Globally, symbiotic nitrogen fixation has been estimated to amount to at least 70 million metric tons of nitrogen per year (Brockwell et al., 1995). Furthermore, in many cases nitrogen fertilizers are not efficiently used by …

The Legume – Rhizobia Symbiosis. Does It Vary For The Tropics Relative To The Mediterranean Basin?, J. G. Howieson, A. Mcinnes

IGC Proceedings (1993-2023)

Symbiotic N fixation from legumes is one of the most important biological processes on the planet. It currently provides the majority of the N requirement in agriculture, yet will have to double if cereal crop production is to meet world demand by 2020 (Kennedy and Cocking 1997). To effectively harness the value of biological N fixation from legumes we need to more fully understand G² x E; where G refers to the genotypes of both the legume (G_l) and its microsymbiont (rhizobia; G_r), and E refers to the edaphic environment in which the symbiosis is …

Advances In Forage Legumes: Shrub Legumes, M. H. Shelton

IGC Proceedings (1993-2023)

Forage tree legumes benefit agriculture through their multi-purpose contributions to livestock feeding, to productivity of farming systems, and to protection of the environment.

Of the several hundred forage tree legume species regarded as having potential for forage only c. twenty are in common use. These are listed together with their agroecological range and tolerance of adverse environments including acid soils, cool temperatures, low rainfall, poor drainage and high salinity. The value of many species to ruminants is limited due to low nutritive value arising from low protein availability and low acceptability caused principally by high condensed tannin content. Only 10 …

Alfalfa, J. H. Bouton

IGC Proceedings (1993-2023)

Cultivated alfalfa or lucerne (Medicago sativa spp. sativa) is the most important forage legume in the world with approximately 32 million hectares cultivated mainly in the temperate regions of both the northern and southern hemispheres. Intensive research has been conducted on the management and physiology of the crop and a major seed industry has developed world wide. Since insect and disease pests are numerous in alfalfa, development of cultivars with the proper fall dormancy and a broad genetic base for pest resistance has been pursued in order to provide increased adaptation, persistence, and yield. There has been a …

Carbon And Nitrogen Isotopic Discrimination In Alfalfa For High Yield And Quality Forage, W. S. Oliveira, P. P. A. Oliveira, M. Corsi, S. M. Tsai

IGC Proceedings (1993-2023)

Biological nitrogen fixation and assimilation of CO₂ can be indirectly monitored in alfalfa (Medicago sativa L.) through the variation of the stable N and C isotopes in the plant (Δ values). Such measurements result in a simple, non-destructive and reliable method for identification of alfalfa cultivars of high yield and nutritional quality. A program for selection of 12 alfalfa cultivars under field and controlled conditions (lysimeters) included determination of biomass and N accumulation. Under controlled conditions yields ranged from 1.77 to 2.47 ton/ha/month (Pioneer 5312 and WL-605) and N2-fixed varied from 77.43 to 84.01% for total N (Brazilian …

A Complete Characterisation Of Vertex-Multiplications Of Trees With Diameter 5, Willie Han Wah Wong, Eng Guan Tay

Theory and Applications of Graphs

For a connected graph G, let D(G) be the family of strong orientations of G; and for any D ∈ D(G), we denote by d(D) the diameter of D. The orientation number of G is defined as d(G)=min{d(D) | D ∈ D(G)}. In 2000, Koh and Tay introduced a new family of graphs, G vertex-multiplications, and extended the results on the orientation number of complete n-partite graphs. Suppose G has the vertex set V(G)={v₁,v₂,… v_n}. For any sequence of n positive integers (s …

Analysis Of Ritalin Addiction And Recovery From Both A Physical And Psychological Lens, Nicole Madrigal, Tyler Marshall

Fall Showcase for Research and Creative Inquiry

We will investigate the physical impacts, both short and long-term effects, of substance use. In doing so, we will frame an argument for the substance's addictive properties as it relates to both its physically addictive and sociological addictive properties. In doing so, a stronger understanding of how an individual can move through the stages of substance use, to abuse, and finally addiction will be reviewed. We will then address current treatment strategies for the substance and how they address or fail to address both the physical and sociological impacts of its use.

The Profound Photophysical Effects Of Organic Chromophore Connectivity And Coupling, David J. Walwark Jr

Nanoscience and Microsystems ETDs

Through-bond and through-space interactions between chromophores are shown to have wide-ranging effects on photophysical outcomes upon light absorption in organic molecules. In collapsed poly(3-hexylthiophene), through-space coupling creates hybrid chromophores that act as energy sinks for nearby excitons and favorable sites for molecular oxygen to dock. Upon excitation with visible light the highly-coupled chromophores react with the docked oxygen and subsequently do not quench nearby excitons as efficiently. In tetramer arrays of perylene diimide chromophores the central moiety through-bond connectivity is synthesized in two variants which exhibit vastly different single-molecule blinking behavior and theoretically-predicted electronic transition character. In the more-connected tetramer …

A Practical Solution: The Anthropocene Is A Geological Event, Not A Formal Epoch, Philip L. Gibbard, Andrew M. Bauer, Matthew Edgeworth, William F. Ruddiman, Jacquelyn L. Gill, Dorothy J. Merritts, Stanley C. Finney, Lucy E. Edwards, Michael J. C. Walker, Mark Maslin, Erle C. Ellis

Biology and Ecology Faculty Scholarship

The Anthropocene has yet to be defined in a way that is functional both to the international geological community and to the broader fields of environmental and social sciences. Formally defining the Anthropocene as a chronostratigraphical series and geochronological epoch with a precise global start date would drastically reduce the Anthropocene’s utility across disciplines. Instead, we propose the Anthropocene be defined as a geological event, thereby facilitating a robust geological definition linked with a scholarly framework more useful to and congruent with the many disciplines engaging with human-environment interactions. Unlike formal epochal definitions, geological events can recognize the spatial and …

A 6-Cpg Validated Methylation Risk Score Model For Metabolic Syndrome: The Hypergen And Goldn Studies, Bertha A. Hidalgo, Bre Minniefield, Amit Patki, Rikki Tanner, Minoo Bagheri, Hemant K. Tiwari, Donna K. Arnett, Marguerite Ryan Irvin

Epidemiology and Environmental Health Faculty Publications

There has been great interest in genetic risk prediction using risk scores in recent years, however, the utility of scores developed in European populations and later applied to non-European populations has not been successful. The goal of this study was to create a methylation risk score (MRS) for metabolic syndrome (MetS), demonstrating the utility of MRS across race groups using cross-sectional data from the Hypertension Genetic Epidemiology Network (HyperGEN, N = 614 African Americans (AA)) and the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN, N = 995 European Americans (EA)). To demonstrate this, we first selected cytosine-guanine dinucleotides …

Analysis Of Fluoxetine (Prozac) Addiction And Recovery From Both A Physical And Psychological Lens, Kristen Dobek, Hannah Couch

Fall Showcase for Research and Creative Inquiry

We will investigate the physical impacts both short and long term effects of of substance use. In doing so we will frame an argument for the substance's addictive properties as it relates to both its physically addictive and sociological addictive properties. In doing, so a stronger understanding of how an individual can move through the stages of substance use, to abuse, and finally addiction will be reviewed. We will then address current treatment strategies for the substance and how they address or fail to address both the physical and sociological impacts of its use.

Non-Local Approximation Properties, Kira Pierce

Fall Showcase for Research and Creative Inquiry

This project concerns the approximation properties of a given set where X is a scattered sequence and Ï•(x) = 1/x* ln(1 + x^2 ). Similar approximation sets are commonly used in interpolation problems and are especially helpful due to their Fourier representation. For our work, we will work to prove the following theorem.

Geographic Distribution And History Of Plant Specimens At Longwood University Harvill-Stevens Herbarium, Ross Bechtle

Fall Showcase for Research and Creative Inquiry

Herbaria are plant museums comprising collections of dried mounted plant specimens crucial for education, research, and conservation purposes. They provide a permanent record of plant diversity found in a particular area over time. An understanding of geographic coverage and history of collection of specimens in a herbarium is important for future planning and growth of a herbarium. The purpose of this study was to understand the county-level distribution and chronology of collection of plant specimens housed in Harvill-Stevens Herbarium at Longwood. Harvill-Stevens Herbarium is the largest collection of Virginia native plants the second largest herbarium in the state consisting of …

Peruvian Fur Seals As Archivists Of El Niño Southern Oscillation Effects, Mickie Rae Edwards, Susana Cardenas-Alayza, Michael Adkesson, Mya Daniels-Abdulahad, Amy Hirons

Marine & Environmental Sciences Faculty Articles

Peru’s coastal waters are characterized by significant environmental fluctuation due to periodic El Niño- La Niña- Southern Oscillation (ENSO) events. This variability results in ecosystem-wide food web changes which are reflected in the tissues of the Peruvian fur seal (Arctocephalus australis). Stable isotope ratios (δ¹³C and δ¹⁵N) in Peruvian fur seal vibrissae (whiskers) are used to infer temporal primary production and dietary variations in individuals. Sea surface temperature anomaly (SSTA) recordings from the Niño 1+2 Index region captured corresponding ENSO conditions. Fluctuations in δ¹⁵N values were correlated to SSTA records, indicating that …

Mgrre_Pureoilscouttickets_Kyncl, Jos & Marie_1_21127118890000, Mgrre

Legacy Scout Tickets from Pure Oil Company

No abstract provided.

Cognizant Composites: Seamless Integration Of Circuitry And Sensors Into Structural Composites, Reuben Fresquez

Computer Science ETDs

This thesis describes a set of novel techniques for embedding sensors, circuitry, and electronics into structural composites. I leverage recent developments in human computer interaction to create sensors and circuitry that are seamlessly incorporated into structural composites. I fabricate bend and compression sensors, along with circuitry, from textiles, which enables me to add electronic capabilities without impacting the composite’s structural integrity. I describe the construction of these “cognizant composites” and demonstrate their functionality. I also explore techniques for embedding standard electronic components, including microcontrollers, into structural composites. Potential applications of this technology include buildings that can warn occupants if load-bearing …

The Birth And Incision History Of The San Juan River In The Past 5 Ma, Micael T. Albonico

Earth and Planetary Sciences ETDs

This study addresses the evolution of the San Juan River system and its confluence with the Colorado River, ~ 100 km above the regionally important Lees Ferry knickzone. The San Juan River is a 600-km-long continental-scale tributary of the Colorado River. From its headwaters in the San Juan Mountains in Colorado, the San Juan River flows across the Colorado Plateau, and into the Colorado River upstream of Grand Canyon. Published apatite fission track and apatite (U-Th)/He thermochronologic data show that rocks in Marble Canyon, as well as in middle and upper reaches of the San Juan River, were >75 °C …

Covering By Homothets And Illuminating Convex Bodies, Alexey Glazyrin

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

The paper is devoted to coverings by translative homothets and illuminations of convex bodies. For a given positive number α and a convex body B, gα⁡(B) is the infimum of α-powers of finitely many homothety coefficients less than 1 such that there is a covering of B by translative homothets with these coefficients. hα⁡(B) is the minimal number of directions such that the boundary of B can be illuminated by this number of directions except for a subset whose Hausdorff dimension is less than α. In this paper, we prove that gα⁡(B)≤hα⁡(B), find upper and lower bounds for both numbers, …

Pseudo-Peakons And Cauchy Analysis For An Integrable Fifth-Order Equation Of Camassa-Holm Type, Enrique G. Reyes, Mingxuan Zhu, Zhijun Qiao

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

In this paper we introduce a hierarchy of integrable higher order equations of Camassa-Holm (CH) type, that is, we present infinitely many nonlinear equations depending on inertia operators which generalize the standard momentum operator A2=∂xx−1 appearing in the Camassa-Holm equation mt=−mxu−2mux, m=A2(u). Our higher order CH-type equations are integrable in the sense that they possess an infinite number of local conservation laws, quadratic pseudo-potentials, and zero curvature formulations. We focus mainly on the fifth order CH-type equation and we show that it admits {\em pseudo-peakons}, this is, bounded solutions with differentiable first derivative and continuous and bounded second derivative, but …

Exploring The Geometric And Electronic Properties Of Palladium Doped Silicon Clusters, Madison Winkeler, Ciara N. Richardson

Scholars Week

Transition metal-doped silicon clusters have unique properties and have been studied as building blocks for nanomaterials and microelectronics. Here, the structure and properties of candidate palladium doped silicon clusters (SinPd2: n=1-17) were determined using global optimization techniques on a high performance computing cluster at the San Diego Supercomputing Center. Then geometric structures were further optimized utilizing the B3LYP method with 6-311+G(d) basis sets for silicon and lanl2dz pseudopotential for palladium, followed by the larger DSDPBEP86 method with 6-311+G(2d) basis sets for silicon and SDD pseudopotential for palladium, as implemented in the Gaussian 16 program package. The energetics for each cluster …

An Efficient High-Order Meshless Method For Advection-Diffusion Equations On Time-Varying Irregular Domains, Varun Shankar, Grady B. Wright, Aaron L. Fogelson

Mathematics Faculty Publications and Presentations

We present a high-order radial basis function finite difference (RBF-FD) framework for the solution of advection-diffusion equations on time-varying domains. Our framework is based on a generalization of the recently developed Overlapped RBF-FD method that utilizes a novel automatic procedure for computing RBF-FD weights on stencils in variable-sized regions around stencil centers. This procedure eliminates the overlap parameter δ, thereby enabling tuning-free assembly of RBF-FD differentiation matrices on moving domains. In addition, our framework utilizes a simple and efficient procedure for updating differentiation matrices on moving domains tiled by node sets of time-varying cardinality. Finally, advection-diffusion in time-varying domains …

Molecular Design Of Polymer Coatings Capable Of Photo-Triggered Stress Relaxation Via Dynamic Covalent Bond Exchange, Autumn M. Mineo, Maren E. Buck, Reika Katsumata

Chemistry: Faculty Publications

Polymer coatings are frequently used to modify surface properties of inorganic substrates. However, the disparity in physical properties between polymer film and substrate often leads to residual stress development, which can be deleterious to the overall performance of coated materials. This work reports the molecular design of polymer films that dissipate stress upon irradiation with ultraviolet (UV) light. These polymers are synthesized by post-polymerization modification of the reactive polymer, poly(2-vinyl-4,4-dimethyl azlactone), to introduce dynamic crosslinks capable of light-initiated addition transfer fragmentation chemistry. Using a custom-built optical cantilever, contrasting film stress responses are observed between films containing dynamic bonds and analogous …

Lignin, Sugar, And Furan Production Of Industrial Hemp Biomass Via An Integrated Process, Jikai Zhao, Jason Griffin, Kraig Roozeboom, Juhee Lee, Donghai Wang

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Traditional pretreatment of lignocellulosic biomass is often accompanied by washing and disposal of wastewater, which leads to overuse of water and loss of by-products. The objectives of this study were to validate the potential of an acid-base integrated process for simultaneous sugars, furans, and lignin production without washing and wastewater discarding. The difference in conversion performance among different biomass resources was also demonstrated. Parallel acetic acid (HOAc, pH = 2.25) and sodium hydroxide (NaOH, pH = 13.46) pretreatments followed by solid and liquid integration were applied to four genotypes of industrial hemp (Cannabis sativa L.) biomass that were harvested …

All-Sky Search For Long-Duration Gravitational-Wave Bursts In The Third Advanced Ligo And Advanced Virgo Run, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Tiffany Z. Summerscales

Faculty Publications

After the detection of gravitational waves from compact binary coalescences, the search for transient gravitational-wave signals with less well-defined waveforms for which matched filtering is not well suited is one of the frontiers for gravitational-wave astronomy. Broadly classified into “short” ≲1  s and “long” ≳1  s duration signals, these signals are expected from a variety of astrophysical processes, including non-axisymmetric deformations in magnetars or eccentric binary black hole coalescences. In this work, we present a search for long-duration gravitational-wave transients from Advanced LIGO and Advanced Virgo’s third observing run from April 2019 to March 2020. For this search, we use …

Reducing Kidney Discard With Artificial Intelligence Decision Support: The Need For A Transdisciplinary Systems Approach, Richard Threlkeld, Lirim Ashiku, Casey I. Canfield, Daniel Burton Shank, Mark A. Schnitzler, Krista L. Lentine, David A. Axelrod, Anil Choudary Reddy Battineni, Henry Randall, Cihan H. Dagli

Engineering Management and Systems Engineering Faculty Research & Creative Works

Purpose of Review: A transdisciplinary systems approach to the design of an artificial intelligence (AI) decision support system can more effectively address the limitations of AI systems. By incorporating stakeholder input early in the process, the final product is more likely to improve decision-making and effectively reduce kidney discard.

Recent Findings: Kidney discard is a complex problem that will require increased coordination between transplant stakeholders. An AI decision support system has significant potential, but there are challenges associated with overfitting, poor explainability, and inadequate trust. A transdisciplinary approach provides a holistic perspective that incorporates expertise from engineering, social science, and …

Stolon Growth And Its Morphological Components In White Clover (Trifolium Repens L.) Cultivars, Omar Scheneiter, E. M. Pagano

IGC Proceedings (1993-2023)

A trial was performed to study the seasonal changes in stolon growth and its morphological components in four white clover cultivars, in the north of Buenos Aires Province, in Argentina. Stolons were tagged in four seasonal measurements periods per year, during two consecutive years. Leaf, stolon and flowerheads weights were recorded at regular intervals in each measurement period and total stolon growth was calculated. Differences among cultivars were found in stolon growth and its morphological components in most of the measurement periods. In spring and summer, differences among cultivars in stolon growth were related to flowering quantity and earliness, and …

Yellow-Flowered Lucerne (Medicago Falcata L.) - A Potential Forage Legume For The North, T. Mela, H. Ihamäki, M. Matilainen

IGC Proceedings (1993-2023)

The suitability of yellow-flowered lucerne (Medicago falcata L.) for forage production under the northern conditions was studied in a mixture sward with timothy (Phleum pratense L.) in field trials in South Finland for four years from 1995 to 1998. Through the first three winters lucerne stayed unharmed. In June and July lucerne grew vigorously, but in August little. The total seasonal yields were highest in the second and the third year of harvesting, up to 10 t DM ha^-1. In the winter 1997-1998 , winter damages killed 21 to 38 % of lucerne plants, and resulted …

Dry Matter Production Of Shoots And Root Density Of Two Cultivars Of Lablab Purpureus (L.) Sweet, L. R. De A. Rodrigues, T. J. D. Rodrigues, A. K. B. Ramos, D. G. De Quadros

IGC Proceedings (1993-2023)

This experiment was conducted in green house conditions to evaluate the DM accumulation in the shoots and in the roots of two cultivars of Lablab purpureus (L.) Sweet. A 2x3 factorial (two cultivars and three evaluation dates) was conducted according to a randomized complete block design with four replications, being the cultivars Highworth and Rongai evaluated at 42, 56, and 70 days after seedling emergence (DASE). The results indicated that the cvs. Highworth and Rongai have the same pattern of DM accumulation in the shoots. In the upper layer of the soil (0-0.20 m) it was found 38.83% and 43.64% …

Role Of White Clover In The Improvement Of Economical Efficiency Of Feeds From Grasslands, P. Goliñski

IGC Proceedings (1993-2023)

The aim of the research was to analyse the role played by white clover in the improvement of economical efficiency of feeds obtained from permanent grasslands. The influence of the proportion of white clover in the pasture sward on unit production costs of yield, energy and crude protein and the profit threshold in milk production was analysed taking into account three white clover cultivars, nitrogen fertilisation, irrigation and overdrilling. The investigation procedures employed the author’s own calculation models elaborated in optimisation programs based on production conditions found in dairy farms in the region of Wielkopolska. It was proved that the …