Physical Sciences and Mathematics Commons^™

Upper Bounds On The Splitting Of The Eigenvalues, Phuoc L. Ho

University of Kentucky Doctoral Dissertations

We establish the upper bounds for the difference between the first two eigenvalues of the relative and absolute eigenvalue problems. Relative and absolute boundary conditions are generalization of Dirichlet and Neumann boundary conditions on functions to differential forms respectively. The domains are taken to be a family of symmetric regions in Rⁿ consisting of two cavities joined by a straight thin tube. Our operators are Hodge Laplacian operators acting on k-forms given by the formula Δ^(k) = dδ+δd, where d and δ are the exterior derivatives and the codifferentials respectively. A result …

In Vivo Oxidative Stress In Alzheimer Disease Brain And A Mouse Model Thereof: Effects Of Lipid Asymmetry And The Single Methionine Residue Of Amyloid-Β Peptide, Miranda Lu Bader Lange

University of Kentucky Doctoral Dissertations

Studies presented in this dissertation were conducted to gain more insight into the role of phospholipid asymmetry and amyloid-β (Aβ)-induced oxidative stress in brain of subjects with amnestic mild cognitive impairment (aMCI) and Alzheimer disease (AD). AD is a largely sporadic, age-associated neurodegenerative disorder clinically characterized by the vast, progressive loss of memory and cognition commonly in populations over the age of ~65 years, with the exception of those with familial AD, which develop AD symptoms as early as ~30 years-old. Neuropathologically, both AD and FAD can be characterized by synapse and neuronal cell loss in conjunction with accumulation of …

The No. 5 Block In Eastern Kentucky: A Critical Re-Examination Of The Petrology With Special Attention To The Origin Of Inertinite Macerals In The Splint Lithotypes, Allison Ranae Richardson

University of Kentucky Master's Theses

Microbes, including fungi and bacteria, and insects are responsible for the consumption and subsequent degradation of plant materials into humus. These microbes directly and indirectly affect the physical and chemical characteristics of coal macerals. Efforts to understand and determine the origins of inertinite macerals are largely misrepresented in the literature, conforming to a single origin of fire. This study focuses on the variability of physical and inferred chemical differences observed petrographically between the different inertinite macerals and discusses the multiple pathways plant material may take to form and or degrade these macerals.

Petrographic results show that fungal activity plays a …

Latest Quaternary Paleoclimate Reconstruction Utilizing Stable Isotopic And Trace Element Proxies In A Stalagmite From Culverson Creek Cave, West Virginia, Ashley Nicole Gilbert

University of Kentucky Master's Theses

A reconstruction of regional climate variability in southern West Virginia that spans the last glacial/interglacial transition is presented. Paleoclimate interpretations obtained from the 50-cm long stalagmite provide key insights regarding the timing, magnitude, and forcing mechanisms responsible for past climate variability. Stable isotopic (δ¹⁸O and δ¹³C) and trace element (Ba, Sr, Mg) signatures from samples contiguously milled along the growth-axis of a ²³⁰Th-dated stalagmite which grew between approximately 20 and 5 thousand years before present (kyr BP) provide critical constraints for above-cave mean annual temperature, seasonality of moisture mean annual precipitation, and potential vegetation shifts. …

Summary Of Kentucky River Watershed Watch 2010 Water Sampling Results, Kentucky Water Resources Research Institute

Kentucky River Watershed Watch

No abstract provided.

Building Sustainable Societies: Exploring Sustainability Policy And Practice In The Age Of High Consumption, Cindy Isenhour

University of Kentucky Doctoral Dissertations

This dissertation is an attempt to examine how humans in wealthy, post-industrial urban contexts understand sustainability and respond to their concerns given their sphere of influence. I focus specifically on sustainable consumption policy and practice in Sweden, where concerns for sustainability and consumer-based responses are strong. This case raises interesting questions about the relative strength of sustainability movements in different cultural and geo-political contexts as well as the specific factors that have motivated the movement toward sustainable living in Sweden.

The data presented here supports the need for multigenic theories of sustainable consumerism. Rather than relying on dominant theories of …

Opioid-Cannabinoid Codrugs With Enhanced Analgesic And Pharmacokinetic Profile, Harpreet Kaur Dhooper

University of Kentucky Doctoral Dissertations

The central hypothesis of the dissertation is that “the design and synthesis of a codrug of an opiate and a cannabinoid can be achieved which is stable in the gastrointestinal tract and shows a superior pharmacological and pharmacokinetic profile when compared to a physical mixture of the two parent drugs.” To prove the hypothesis, a series of novel codrugs were prepared by conjugation of the opiate drug codeine with Δ⁹-tetrahydrocannabinol (Δ⁹-THC), cannabidiol, abn-cannabidiol and an opiate prodrug 3-O-acetylmorphine with Δ⁹-THC. Codeine-cannabinoid codrugs were evaluated for analgesic activity in the rat after oral administration. The …

Non-Portland Cement Activation Of Blast Furnace Slag, Anne Elizabeth Oberlink

University of Kentucky Master's Theses

The purpose of this project was to produce a “greener” cement from granulated ground blast furnace slag (GGBS) using non-Portland cement activation. By eventually developing “greener” cement, the ultimate goal of this research project would be to reduce the amount of Portland cement used in concrete, therefore reducing the amount of carbon dioxide emitted into the atmosphere during cement production.

This research studies the behavior of mineral binders that do not contain Portland cement but instead comprise GGBS activated by calcium compounds or fluidized bed combustion (FBC) bottom ash. The information described in this paper was collected from experiments including …

Hydraulic Geometry Relationships And Regional Curves For The Inner And Outer Bluegrass Regions Of Kentucky, Ruth Roseann Brockman

University of Kentucky Master's Theses

Hydraulic geometry relationships and regional curves are used in natural channel design to assist engineers, biologists, and fluvial geomorphologists in the efforts undertaken to ameliorate previous activities that have diminished, impaired or destroyed the structure and function of stream systems. Bankfull channel characteristics were assessed for 14 United States Geological Survey (USGS) gaged sites in the Inner Bluegrass and 15 USGS gaged sites in the Outer Bluegrass Regions of Kentucky. Hydraulic geometry relationships and regional curves were developed for the aforementioned regions.

Analysis of the regression relationships showed that bankfull discharge is a good explanatory variable for bankfull parameters such …

Kentucky Water Resources Research Institute Annual Technical Report Fy 2009, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The 2009 Annual Technical Report for Kentucky consolidates reporting requirements of the Section 104(b) base grant award into a single document that includes: 1) a synopsis of each research project conducted with grant funds during the period, 2) citations for related publications, reports, and presentations, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable awards and achievements during the year.

Characterization Of Soil Carbon Stabilization In Long-Term Row-Cropped Agro-Ecosystems, Soraya Patricia Alvarado-Ochoa

University of Kentucky Doctoral Dissertations

Soil organic matter (SOM) is a dynamic soil property, sensitive and responsive to many factors. The possibility of increasing soil carbon (C) sequestration by changing land use and management practices has been of great interest recently due to concerns with global changes in the atmospheric carbon dioxide (CO₂) balance. Nonetheless, as a result of the complex dynamics of SOM, there is still the need for SOM characterization procedures capable of monitoring SOM stabilization, taking into account all the factors involved.

This study characterized SOM stabilization as affected by management practices in three long-term field experiments, considering physical, chemical …