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Full-Text Articles in Physical Sciences and Mathematics

Glitch Estimation And Removal Using Adaptive Spline Fitting And Wavelet Shrinkage On The Gravitational Wave Data, Mohammad Abu Thaher Chowdhury Dec 2022

Glitch Estimation And Removal Using Adaptive Spline Fitting And Wavelet Shrinkage On The Gravitational Wave Data, Mohammad Abu Thaher Chowdhury

Theses and Dissertations

The false alarm rate and reduced sensitivity of searches for astrophysical signals are caused by transient signals of earthly origin, or "glitches," in gravitational wave strain data from groundbased detectors. The greater number of observable astrophysical signals will increase the likelihood of glitch overlaps and exacerbate their negative impact for future detectors with higher sensitivities. The wide morphological diversity and unpredictable waveforms of glitches, and with the vast majority of cases lacking supplemental data present the main obstacles to their mitigation. Thus, nonparametric glitch mitigation techniques are required, which should operate for a wide range of glitches and, in the …


Search For Gravitational Waves From Core Collapse Supernovae In Ligo's Observation Runs Using A Network Of Detectors, Shahrear Khan Faisal Dec 2022

Search For Gravitational Waves From Core Collapse Supernovae In Ligo's Observation Runs Using A Network Of Detectors, Shahrear Khan Faisal

Theses and Dissertations

Core-Collapse Supernova (CCSN) is one of the most anticipated sources of Gravitational Waves (GW) in the fourth observation run (O4) of LIGO and other network of GW detectors. A very low rate of galactic CCSN, coupled with the fact that the CCSN waveforms are unmodeled, make detection of these signals extremely challenging. Mukherjee et. al. have developed a new burst search pipeline, the Multi-Layer Signal Enhancement with cWB and CNN or MuLaSEcC, that integrates a non-parametric signal estimation and Machine Learning. MuLaSEcC operates on GW data from a network of detectors and enhances the detection probability while reducing the false …


Unified Model Of Lightning & Electrostatic Discharges Across The Solar System, Annelisa Blackwell Esparza Dec 2022

Unified Model Of Lightning & Electrostatic Discharges Across The Solar System, Annelisa Blackwell Esparza

Theses and Dissertations

As we increase the number of probes on other objects within our solar system, it becomes all the timelier to understand the physics of electrostatic discharges (ESDs). Since these probes will have sensitive instruments on-board, we will need to apply our existing knowledge of ESDs to extraterrestrial environments to protect these investments from deterioration. On Earth, even small-scale ESDs can permanently destroy critical components within electronics, while large-scale ESDs (e.g., lightning strikes) are capable of debilitating entire power grids. The characteristic timescale of an ESD is small compared to the timescales of cloud charging and storm evolution. This lets us …


Search For Triple-Proton Decay Using Machine Learning With Cuore, Douglas Adams Oct 2022

Search For Triple-Proton Decay Using Machine Learning With Cuore, Douglas Adams

Theses and Dissertations

A framework to search for a triple-proton decay of 130Te in the CUORE detector against a background of muons is presented. We use machine learning to classify different kinds of energy depositing events. We use the classification information to improve our detection or non-detection limits of a triple-proton decay process. We derive and use a methodology of combining Poisson counting statistics with supervised classification machine learning tools. Additionally, a sensitivity calculation is provided which uses the classification counting likelihood. Using our analysis technique, we achieve an lower 2σ half-life bound of 7.43×1024yrs for triple-proton decay of …


Memristive Ising Circuits, Vincent James Dowling Oct 2022

Memristive Ising Circuits, Vincent James Dowling

Theses and Dissertations

Resistance random access memory (ReRAM) cells are emerging passive components showing great promise for applications in non-volatile storage, in-memory computing, and neuromorphic circuits, to name a few. Various experimental ReRAM cells have demonstrated excellent characteristics. This includes nanoscale size, short read and write times, and small energy requirements needed to manipulate the information. The main obstacles preventing the widespread adoption of ReRAM technology are significant device-to-device and cycle-to-cycle variability.

In essence, ReRAM cells are resistors with memory whose state (resistance) can be changed by an applied signal such as voltage. Many models were developed for describing their response. These range …


Magnetic Field Directed Self-Assembly Of Colloidal Nanoparticles Via Extreme Field Gradients Of Magnetic Recording Media, Abdul Rahman Mohtasebzadeh Oct 2022

Magnetic Field Directed Self-Assembly Of Colloidal Nanoparticles Via Extreme Field Gradients Of Magnetic Recording Media, Abdul Rahman Mohtasebzadeh

Theses and Dissertations

Magnetic nanoparticles have been extensively studied over the last half century and continue to sustain interest due to their potential use in different fields. This research explores Magnetic Field Directed Self-Assembly of magnetic nanoparticles using a magnetic disk drive. The magnetic fields generated by the bits in a magnetic disk drive have rapidly changing field gradients that can self-assemble magnetic nanoparticles into various shapes. We demonstrate the ability to record and read field gradients on a commercial disk drive medium and to use monodisperse iron oxide nanoparticles to achieve self-assembly. We use image analysis techniques to quantify parameters related to …


Investigation Of Adhesion, Deformation Mechanics, And Electrical Properties Of Ag/Sio2/Pdms Tri-Layers For Stretchable Electronic Applications, Rhandy Joe Paladines Sep 2022

Investigation Of Adhesion, Deformation Mechanics, And Electrical Properties Of Ag/Sio2/Pdms Tri-Layers For Stretchable Electronic Applications, Rhandy Joe Paladines

Theses and Dissertations

The motivation behind this research is to improve the interfacial layer bonding of metallic thin films to PDMS substrates with the aid of a buffer layer. The physical vapor deposition (PVD) technique of sputtering was used to deposit bilayer thin films of silver (Ag) and silicon dioxide (SiO2) on PDMS. Two chamber pressures were used in this work, 5 and 20 mTorr, to investigate the role of this parameter in determining the interfacial adhesion and the role in determining the resistance sensitivity. Studies of the surface energy and increased bonding strength for metallization are carried out. Surface characterization using atomic …


Quantum Error Detection Without Using Ancilla Qubits, Nicolas Guerrero Sep 2022

Quantum Error Detection Without Using Ancilla Qubits, Nicolas Guerrero

Theses and Dissertations

Quantum computers are beset by errors from a variety of sources. Although quantum error correction and detection codes have been developed since the 1990s, these codes require mid-circuit measurements in order to operate. In order to avoid these measurements we have developed a new error detection code that only requires state collapses at the end of the circuit, which we call no ancilla error detection (NAED). We investigate some of the mathematics behind NAED such as which codes can detect which errors. We then run NAED on three separate types of circuits: Greenberger–Horne–Zeilinger circuits, phase dependent circuits, and a quantum …


Optimizing Optical Switching Of Non-Linear Optimizing Optical Switching Of Non-Linear Hyperbolic Metamaterials, James A. Ethridge Sep 2022

Optimizing Optical Switching Of Non-Linear Optimizing Optical Switching Of Non-Linear Hyperbolic Metamaterials, James A. Ethridge

Theses and Dissertations

Modern optical materials are engineered to be used as optical devices in specific applications, such as optical computing. For optical computing, efficient forms of a particular device, the optical switch, still have not been successfully demonstrated. This problem is addressed in this research through the use of designed optical metamaterials, specifically, hyperbolic metamaterials, which offer the possibility of large non-linear properties with a low switching intensity. One-dimensional layered hyperbolic metamaterials composed of alternating layers of metal and dielectric were used here, with ITO as the metal and SiO2 as the dielectric. The non-linear behavior of the ITO/SiO2 layered …


Enabling Rapid Chemical Analysis Of Plutonium Alloys Via Machine Learning-Enhanced Atomic Spectroscopy Techniques, Ashwin P. Rao Sep 2022

Enabling Rapid Chemical Analysis Of Plutonium Alloys Via Machine Learning-Enhanced Atomic Spectroscopy Techniques, Ashwin P. Rao

Theses and Dissertations

Analytical atomic spectroscopy methods have the potential to provide solutions for rapid, high fidelity chemical analysis of plutonium alloys. Implementing these methods with advanced analytical techniques can help reduce the chemical analysis time needed for plutonium pit production, directly enabling the 80 pit-per-year by 2030 manufacturing goal outlined in the 2018 Nuclear Posture Review. Two commercial, handheld elemental analyzers were validated for potential in situ analysis of Pu. A handheld XRF device was able to detect gallium in a Pu surrogate matrix with a detection limit of 0.002 wt% and a mean error of 8%. A handheld LIBS device was …


Efficiency Quantification For Pulsed-Source Digital Holographic Wavefront Sensing, Steven A. Owens Sep 2022

Efficiency Quantification For Pulsed-Source Digital Holographic Wavefront Sensing, Steven A. Owens

Theses and Dissertations

The efficiencies of a digital holography (DH) system in the pulsed configuration and the off-axis image plane recording geometry are analyzed. First, the system efficiencies of an infrared-wavelength DH system in a homodyne-pulsed configuration are measured and compared to those of a visible-wavelength DH system in a homodyne-continuous-wave (CW) configuration. The total-system, excess-reference-noise, shot-noise-limit, and mixing efficiencies of the pulsed-source system were found to be consistent with those of the CW-source system. This indicated no new efficiencies were necessary to characterize pulsed-source systems when no temporal delay exists between the pulses. The consistency of efficiencies also showed infrared DH systems …


The Fermilab Spinquest Experiment: Commissioning And Plans Toward Production, Nuwan Chaminda Gunawardhana Waduge Aug 2022

The Fermilab Spinquest Experiment: Commissioning And Plans Toward Production, Nuwan Chaminda Gunawardhana Waduge

Theses and Dissertations

E1039/SpinQuest, a transversely-polarized Drell-Yan experiment at Fermilab, plans to use the 120 GeV proton beam and polarized NH3 and ND3 cryogenic targets to study azimuthal asymmetries in dimuon production to extract the magnitude as well as sign of the sea quarks Sivers functions. The SpinQuest spectrometer is optimized to detect oppositely-charged muons with a series of tracking chambers and hodoscope stations. The scope of this manuscript is to highlight the physics goals and the experimental setup with a focus on the ongoing debugging and training of one of the tracking systems, mainly drift chambers, as preparation for the upcoming commissioning …


Searching For Gravitational Wave Associations With High-Energy Astrophysical Transients, Brandon Joseph Piotrzkowski Aug 2022

Searching For Gravitational Wave Associations With High-Energy Astrophysical Transients, Brandon Joseph Piotrzkowski

Theses and Dissertations

Gravitational waves (GW) have become an invaluable tool in modern astronomy, especiallyin conjunction with other astronomical observations. GWs are created in highly dynamical systems such as compact binary coalescences (CBC) which are comprised of black holes and/or neutron stars. The Laser Interferometer Gravitational Wave Observatory (LIGO), Virgo Observatory, and KAGRA have now collectively identified almost a hundred of these events. GWs have also been predicted to come from core collapse supernovae. Both of these types of systems have been shown to produce other detectable transients, such as gamma- ray bursts (GRB) and neutrino bursts. Observations of the same astrophysical system …


Data-Driven Population Inference From Gravitational-Wave Sources And Electromagnetic Counterparts, Siddharth Mohite Aug 2022

Data-Driven Population Inference From Gravitational-Wave Sources And Electromagnetic Counterparts, Siddharth Mohite

Theses and Dissertations

Gravitational-wave (GW) astronomy has presented an unprecedented way to view the universe and study populations of astrophysical objects such as merging compact binaries containing black holes (BHs) and neutron stars (NSs). With the latest catalog of observations detected by the Advanced LIGO-Virgo detector network, recent analyses are placing interesting constraints on the population of BHs and NSs in these binaries. In particular, we are learning a great deal about how these binaries are distributed as a function of their masses. Another aspect of GW astronomy that has the potential to provide insights into fundamental physics is the multi-messenger follow up …


Study Of Radiative Corrections In The Muon Scattering Experiment, Lin Li Jul 2022

Study Of Radiative Corrections In The Muon Scattering Experiment, Lin Li

Theses and Dissertations

The root-mean-square (rms) radius of the proton charge is a fundamental quantity. In 2010, the studies of muonic hydrogen with high precision found a notably smaller value than the one from earlier non-muonic measurements. This discrepancy has led to theoretical and experimental investigations. A missing measurement in determining the proton radius is muon scattering, a measurement that the MUon Scattering Experiment (MUSE) collaboration proposed at Paul Scherrer Institute (PSI). MUSE will measure elastic electron-proton and muon-proton scattering data with positively and negatively charged beams in a four-momentum-transfer square range from Q2 = 0.002 to 0.08 GeV2 . Each of …


Shadows Of A Schwarzschild Black Hole Surrounded By A Spherically Symmetric Dark Matter, Ahmad Ibrahim Jun 2022

Shadows Of A Schwarzschild Black Hole Surrounded By A Spherically Symmetric Dark Matter, Ahmad Ibrahim

Theses and Dissertations

In this thesis, using general relativity, the null geodesics and black hole shadow of a spherically symmetric configuration of a black hole (surrounded by a dark matter shell) are studied. First, the standard

results of the photon sphere of Schwarzschild de-Sitter black hole is revisited and analyzed more carefully. Secondly, using an ansatz (piecewise metric function) commonly used in the literature to describe the mass distribution of the spherically symmetric black hole - dark matter configuration, the null geodesics through vacuum and dark matter are analyzed. Assuming an observer located at a finite distance from the black hole outside the …


Full Pattern Analysis And Comparison Of The Center Fed And Offset Fed Cassegrain Antennas With Large Focal Length To Diameter Ratios For High Power Microwave Transmission, Derek W. Mantzke Jun 2022

Full Pattern Analysis And Comparison Of The Center Fed And Offset Fed Cassegrain Antennas With Large Focal Length To Diameter Ratios For High Power Microwave Transmission, Derek W. Mantzke

Theses and Dissertations

High power microwaves (HPM) have been a topic of research since the Cold War era. This paper will present a comparison between two Cassegrain-type antennas: the axially, or center fed, and the offset fed. Specifically, the 10 GHz operating frequency will be investigated with large focal length to diameter () ratios. Beam patterns which encompass the entire radiation pattern will be included for data validation and optimization. The simulations will follow a design of experiments factorial model to ensure all possible combinations of prescribed parameters are included, including an analysis of variance (ANOVA) study to find parameter influence on the …


Methods For Focal Plane Array Resolution Estimation Using Random Laser Speckle In Non-Paraxial Geometries, Phillip J. Plummer Jun 2022

Methods For Focal Plane Array Resolution Estimation Using Random Laser Speckle In Non-Paraxial Geometries, Phillip J. Plummer

Theses and Dissertations

The infrared (IR) imaging community has a need for direct IR detector evaluation due to the continued demand for small pixel pitch detectors, the emergence of strained-layer-super-lattice devices, and the associated lateral carrier diffusion issues. Conventional laser speckle-based modulation transfer function (MTF) estimation is dependent on Fresnel propagation and a wide-sense-stationary input random process, limiting the use of this approach for lambda (wavelength)-scale IR devices. This dissertation develops two alternative methodologies for speckle-based resolution evaluation of IR focal plane arrays (FPAs). Both techniques are formulated using Rayleigh-Sommerfield electric field propagation, making them valid in the non-paraxial geometries dictated for resolution …


Direct Simulation And Reduced-Order Modeling Of Premixed Flame Response To Acoustic Modulation, Zheng Qiao May 2022

Direct Simulation And Reduced-Order Modeling Of Premixed Flame Response To Acoustic Modulation, Zheng Qiao

Theses and Dissertations

This dissertation introduces a general, predictive and cost-efficient reduced-order modeling (ROM) technique for characterization of flame response under acoustic modulation. The model is built upon the kinematic flame model–G-equation to describe the flame topology and dynamics, and the novelties of the ROM lie in i) a procedure to create the compatible base flow that can reproduce the correct flame geometry and ii) the use of a physically-consistent acoustic modulation field for the characterization of flame response. This ROM addresses the significant limitations of the classical kinematic model, which is only applicable to simple flame configurations and relies on ad-hoc models …


Construction And Testing Of Large-Area Gem Detectors For The Forward Muon Endcap Upgrade Of The Cms Experiment And Vector-Portal Search For Dark Matter Particles With Dimuon Pairs At √S = 13 Tev, Mehdi Rahmani May 2022

Construction And Testing Of Large-Area Gem Detectors For The Forward Muon Endcap Upgrade Of The Cms Experiment And Vector-Portal Search For Dark Matter Particles With Dimuon Pairs At √S = 13 Tev, Mehdi Rahmani

Theses and Dissertations

In this thesis, I present my contributions to the second major upgrade of the Compact Muon Solenoid at the Large Hadron Collider and the analysis that I performed on the data collected by the Compact Muon Solenoid during the 2018 and 2017 era. Alongside my team, I assembled and tested ten Gaseous Electron Multipliers to upgrade the forward region at the Compact Muon Solenoid, all of which are now installed at the dedicated stations. The campaign for producing these detectors succeeded in a twoyear-long prototyping endeavor, where I examined the procedural steps for production to optimize the production and testing …


Application Of The Test For Memristor To Experimental Memory Devices, Jinsun Kim Apr 2022

Application Of The Test For Memristor To Experimental Memory Devices, Jinsun Kim

Theses and Dissertations

In early seventies, the memristor was introduced as the fourth fundamental nonlinear two-terminal circuit element coupling the charge and flux by Dr. L. Chua. In 2008, the experimental discovery of the memristor was announced triggering significant interest in the development of resistance switching memory devices and their applications. According to Chua, the pinched hysteresis loop in the current-voltage characteristic of experimental memory devices is the fingerprint of memristors (“if it’s pinched it’s a memristor”). However, such loops are not an exclusive feature of memristors as they are also found in the response of other devices with memory that are not …


Formulation And Characterization Of Fast-Curing Plastic Scintillators With High-Z Loading, Theodore W. Stephens Mar 2022

Formulation And Characterization Of Fast-Curing Plastic Scintillators With High-Z Loading, Theodore W. Stephens

Theses and Dissertations

Development of novel fast-curing plastic scintillators is highly advantageous due to their potential to be manufactured via 3D printing. Several formulations were developed that exhibit enhanced photon sensitivity, producing modest but discernible photopeaks at an incident gamma energy of 122 keV. The photon sensitivity is achieved via bismuth high-Z loading; however, this practice typically results in diminished light yields. Subsequent formulations, which varied the photoinitiator concentration and curing time, demonstrated successful curing with sufficient plastic hardness, reduced purple discoloration, reduced heat buildup during curing, and resulted in less cracking during the curing process, all of which were correlated with lower …


Directionally Sensitive Gamma Imaging Using Rotating Scatter Masks And Inexpensive, Scintillation Detectors, Christopher S. Charles Mar 2022

Directionally Sensitive Gamma Imaging Using Rotating Scatter Masks And Inexpensive, Scintillation Detectors, Christopher S. Charles

Theses and Dissertations

This work demonstrates the first instantiation of the FitzGerald Rotating Scatter Mask (RSM) as a proof-of-concept for two-dimensional source direction determination using a single, inexpensive, non-cooled scintillator, as well as an alternate mask design for comparison. A large RSM was additively manufactured from low-Z, acrylic like material, and rotated around the ubiquitous standard 3" x 3" NaI(Tl) or NaI(Tl)/CsI(Tl) phoswich detector, set internally to the mask. Smaller versions of the FitzGerald and alternate RSM designs were 3D printed for testing and used in conjunction with a LaBr detector to characterize the RSM system with a size and weight reduction applied. …


Determination Of Vortex Locations In A 2x2 Array Of Josephson Junctions For Topological Quantum Computation, Casey L. Kowalski Mar 2022

Determination Of Vortex Locations In A 2x2 Array Of Josephson Junctions For Topological Quantum Computation, Casey L. Kowalski

Theses and Dissertations

A large barrier to practical quantum computation exists in the form of qubit decoherence, which leads to high noise and error when implementing quantum algorithms. A potential solution to this problem is the use of topologically-protected Majorana-based qubits, as their nonlocal nature and unique non-abelian exchange statistics render them virtually immune to decoherence while still allowing the state to be easily manipulated. For such a qubit to be constructed, it is essential to know the locations of the Majorana-hosting vortices in the system. This work presents a solution for the formation locations of vortices in a 2x2 superconducting island array, …


Characterization Of Environmental Conditioning Of Lithium Hydride Using Spectroscopy And Machine Learning, Ryan E. Pinson Mar 2022

Characterization Of Environmental Conditioning Of Lithium Hydride Using Spectroscopy And Machine Learning, Ryan E. Pinson

Theses and Dissertations

Lithium compounds such as lithium hydride (LiH) and anhydrous lithium hydroxide (LiOH) have various applications in industry but are highly reactive when exposed to moisture and CO2. These reactions create new molecular forms, including compounds such as lithium oxide (Li2O), lithium hydroxide monohydrate (LiOH ·H2O), and lithium carbonate (Li2CO3). These new compounds degrade the effectiveness in applications using these compounds. The negative effects induced by new lithium compounds creates a need for the ability to characterize the in-growth of such compounds. To study these in-growths, this work will present environmental …


Atomistic Simulation Of Na+ And Cl- Ions Binding Mechanisms To Tobermorite 14Å As A Model For Alkali Activated Cements, Ahmed Abdelkawy Jan 2022

Atomistic Simulation Of Na+ And Cl- Ions Binding Mechanisms To Tobermorite 14Å As A Model For Alkali Activated Cements, Ahmed Abdelkawy

Theses and Dissertations

The production of ordinary Portland cement (OPC) is responsible for ~8% of all man-made CO2 emissions. Unfortunately, due to the continuous increase in the number of construction projects, and since virtually all projects depend on hardened cement from the hydration of OPC as the main binding material, the production of OPC is not expected to decrease. Alkali-activated cement produced from the alkaline activation of byproducts of industries, such as iron and coal industries, or processed clays represents a potential substitute for OPC. However, the interaction of the reaction products of AAC with corrosive ions from the environment, such as Cl-, …


Quantum Capacitance Investigation Of Different Tas2 Polymorphs For Energy Storage Applications – First Principles Study, Mahmoud Elattar Jan 2022

Quantum Capacitance Investigation Of Different Tas2 Polymorphs For Energy Storage Applications – First Principles Study, Mahmoud Elattar

Theses and Dissertations

Energy is an essential requirement, which has a growing demand due to the growth of population and the world transformation into electronic. More than 70% of energy resources are fossil-fuel based which has an environmental impact due to the CO2 emissions. Energy hubs for Fossil-fuel to electric energy conversion, controlled CO2 emissions processing units, and energy storage system are key factors for a smooth transition to green energy without lack of energy supplies, where electrical energy storage systems (ESS) are key enablers to achieve that. One of the effective components which determines the ESS efficiency is the electrode …


Direction Modulated Brachytherapy For The Treatment Of Cervical Cancer, Dylan Richeson Jan 2022

Direction Modulated Brachytherapy For The Treatment Of Cervical Cancer, Dylan Richeson

Theses and Dissertations

Purpose: To evaluate and compare the performance of 9 experimental DMBT tandem models of varying physical dimensions in relation to 24 previously planned HDR cervical cancer treatment plans from multiple institutions that used conventional tandem and rings or ovoid applicators.

Methods and Materials: The DMBT tandem is designed to be used concurrently with IGABT and is made from an MRI-compatible tungsten-alloy rod with 6 channels grooved out of its periphery. 9 experimental DMBT tandem prototypes were provided. Each of the models was of equal lengths but varied in thickness, channel diameter size, and circle channel diameter size. Replanning …


Periodic Trends In The Infrared And Optical Absorption Spectra Of Metal Chalcogenide Clusters, Alain Ward Jan 2022

Periodic Trends In The Infrared And Optical Absorption Spectra Of Metal Chalcogenide Clusters, Alain Ward

Theses and Dissertations

We have investigated the Optical absorption, Infrared spectra, Binding Energies, and various other cluster properties to determine the existence of periodic trend for Transition Metal Chalcogenide Clusters ligated with CO ligands. We were motivated to answer the question of whether periodic behavior can be observed in properties of octahedral metal-chalcogenide clusters. We have used the Amsterdam Density Functional code to calculate the electronic structure of Transition Metal Chalcogenide Clusters using gradient-corrected density functional theory. We determined the existence of several periodic trends in properties of octahedral Transition Metal Chalcogenide Clusters TM6Se8(CO)6. To investigate these …


Development Of Novel Intracavitary Intensity Modulated Brachytherapy Applicators For Optimizing The Target Coverage In Gynecologic Malignancies, Monte Carlo Simulation Dosimetry, Moeen Meftahi Jan 2022

Development Of Novel Intracavitary Intensity Modulated Brachytherapy Applicators For Optimizing The Target Coverage In Gynecologic Malignancies, Monte Carlo Simulation Dosimetry, Moeen Meftahi

Theses and Dissertations

Gynecologic brachytherapy (GYN-BT) is essential for treating cervical and endometrial cancers, the most prevalent female reproductive cancers. This technique enables high radiation doses to a target with rapid dose fall-off to protect adjacent healthy organs. This dissertation aims to address some of the limitations of intracavitary GYN-BT using an intensity modulated brachytherapy (IMBT) technique and Monte Carlo (MC) simulations.

First, a novel non-invasive shielded vaginal cylinder (VC) applicator was designed to provide optimized radiation coverage for the target volume at vaginal apex, site of most recurrences without BT, for endometrial cancer BT. Physical limitations of current applicators and their resulting …