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Full-Text Articles in Physical Sciences and Mathematics

Social Media Marketing Audiences And Adaptive Behavior In Brunei: Sem Analysis Using Smartpls, Shahid Anjum, Asmah Ahmad, Jefri Basiuni, Najeeba Tazeen Jan 2024

Social Media Marketing Audiences And Adaptive Behavior In Brunei: Sem Analysis Using Smartpls, Shahid Anjum, Asmah Ahmad, Jefri Basiuni, Najeeba Tazeen

ASEAN Journal on Science and Technology for Development

The social media and Internet technology penetrations and usage are quite high in Brunei Darussalam. The use of social media marketing among micro, small, and relatively medium businesses to promote their products has also grown as businesses desire to engage and build relationships with customers through social media. This has generated an interest in studying the adaption of social media marketing campaigns among customers, which indirectly determines the effectiveness of social media marketing itself, as well as in studying the facilitation factors for such an adaption. Technology Acceptance Model (TAM) has been used extensively because of its simplicity and usefulness. …


Innovation Barriers Obstructing The Transfer Of Technology From University To Industry In Asean Developing Countries (Case Study On Brunei Darussalam), Rafiq Zaini, Kamariah Ismail Jan 2024

Innovation Barriers Obstructing The Transfer Of Technology From University To Industry In Asean Developing Countries (Case Study On Brunei Darussalam), Rafiq Zaini, Kamariah Ismail

ASEAN Journal on Science and Technology for Development

This study aims to explore the barriers of innovation in one of ASEAN developing countries particularly Brunei Darussalam. This research focuses on 3 sectors which are from 1) the government of Brunei to 2) the higher education institutions particularly Universiti Teknologi Brunei to 3) industry sectors in Brunei Darussalam - primarily in the processes of technology transfer. Using the Triple Helix theory model, barriers were identified between consecutive sectors. In this study, qualitative research methods have been utilized (case studies using interview methods) and a total of 9 main barriers have been identified between the sectors from the literature review …


Does The Foreign Direct Investment In Emerging Asian Countries Get ‘Greased’ Or ‘Sanded’ By Corruption? Evidence From Gets Model, Rainah Ginsad, Imbarine Bujang, Abdul Aziz Karia, Emelia Girau, Siti Rahayu Beli Jan 2024

Does The Foreign Direct Investment In Emerging Asian Countries Get ‘Greased’ Or ‘Sanded’ By Corruption? Evidence From Gets Model, Rainah Ginsad, Imbarine Bujang, Abdul Aziz Karia, Emelia Girau, Siti Rahayu Beli

ASEAN Journal on Science and Technology for Development

Inflows of foreign direct investment (FDI) considerably boost industrialization and economic growth in emerging economies. Corruption, human capital, and the economic environment are just a few factors mentioned in the literature as influencing FDI inflow. The impact of corruption on FDI, whether FDI is greased or sanded by corruption, has received greater interest in recent empirical study. This study analysed the impact of the Corruption Perception Index (CPI) on foreign direct investment (FDI) in selected Asian emerging economies. Utilising annual panel data covering 22 selected Asian emerging economies, this study uses the General-to-specific (GETS) model to analyse the impact. The …


Measurement Accuracy Of Inputs And Outputs For Financial Efficiency Of Islamic Banks, Irma Febriana Mimma Kebahyang, Imbarine Bujang, Norhayati Mohamed, Emi Maimunah Jan 2024

Measurement Accuracy Of Inputs And Outputs For Financial Efficiency Of Islamic Banks, Irma Febriana Mimma Kebahyang, Imbarine Bujang, Norhayati Mohamed, Emi Maimunah

ASEAN Journal on Science and Technology for Development

This paper aims to conduct a systematic literature review on the measurement accuracy of Inputs and Outputs for the financial efficiency of Islamic Banks. Generally, financial efficient literature has lengthy discussions of various input and output measurements, but the research findings are still arguably among scholars. Therefore, this paper highlighted the significance of input and output that reflects the accuracy of the financial efficiency measurement. The data of this study was derived from a review of empirical literature comprising 33 articles published between 2013 and 2023. The sample articles on the Islamic Banks' financial efficiency measurement were located through a …


A Beacon Of Climate Change And Green Financing Toward Bank Stability Among Tiger Cub Economics, Mohd Razuan Abd Hishamuddin, Imbarine Bujang, Flicia Rimin, Irma Febriana Mimma Kebahyang Jan 2024

A Beacon Of Climate Change And Green Financing Toward Bank Stability Among Tiger Cub Economics, Mohd Razuan Abd Hishamuddin, Imbarine Bujang, Flicia Rimin, Irma Febriana Mimma Kebahyang

ASEAN Journal on Science and Technology for Development

Economic growth strongly depends on financial stability, given that the financial sector conducts most transactions in the real economy. Financial instability causes banking institutions to be wary about backing profitable businesses, resulting in a reluctance to fund such activities. Green financing is one of the measures to minimize banking instability. In general, the role of green financing would be to mitigate climate change risk and control the environment. Numerous studies have been conducted on an empirical model of the relationship between climate change and the financial stability of banking institutions. However, little emphasis is placed on the context of adopting …


The Interaction Of Maqasid Al-Shariah In The Relationship Between Esg And Firm Financial Performance, Dayang Nuradzlina Radin, Norhasimah Shaharuddin, Imbarine Bujang, Igo Febrianto Rijanto Jan 2024

The Interaction Of Maqasid Al-Shariah In The Relationship Between Esg And Firm Financial Performance, Dayang Nuradzlina Radin, Norhasimah Shaharuddin, Imbarine Bujang, Igo Febrianto Rijanto

ASEAN Journal on Science and Technology for Development

This paper aims to analyse the role of Maqasid Al-Shariah as a value-added factor in the implementation of ESG for firms' financial performance. Most publicly listed firms are encouraged to get involved in sustainability reporting; however, the adoption rate of ESG among non-financial firms seems unattractive. Therefore, this paper will evaluate the literature review using the systematic literature review approach to justify the role of Maqasid Al-Shariah in implementing ESG. The general conclusion suggested that ESG plays an essential role in financial performance despite the implementation focusing more on cost. The inclusion of Maqasid Al-Shariah in ESG believes that the …


Molecular Identification To Verify The Existence Of Helicotylenchus Dihystera In Coffee Plants At East Java, Indonesia, Ankardiansyah Pandu Pradana, Toyoshi Yoshiga Jan 2024

Molecular Identification To Verify The Existence Of Helicotylenchus Dihystera In Coffee Plants At East Java, Indonesia, Ankardiansyah Pandu Pradana, Toyoshi Yoshiga

ASEAN Journal on Science and Technology for Development

Spiral nematodes Helicotylenchus sp. are known to infect a variety of plants, including coffee. This is in line with the studies and surveys of nematodes in Indonesia. However, to date, there has been no study reporting the nematode with molecular analysis. In this study, we surveyed the nematodes in Arabica coffee plantations in Bondowoso regency – Indonesia. These spiral nematodes were collected in DESS solution for morphological, morphometric and molecular analysis. The morphometric analysis was carried out under an Olympus BH-2 compound microscope with an attached calibrated Toupcam M20 camera. The molecular analysis was performed on the total DNA from …


On-Site Estimation Of Total Sugars In Flavored Milk Using A Glucometer, Erwin Oliver V. Fundador, Karyn Thea E. Rivera, Kriza Faye A. Calumba, Noreen Grace V. Fundador Jan 2024

On-Site Estimation Of Total Sugars In Flavored Milk Using A Glucometer, Erwin Oliver V. Fundador, Karyn Thea E. Rivera, Kriza Faye A. Calumba, Noreen Grace V. Fundador

ASEAN Journal on Science and Technology for Development

Sugar has been linked to obesity and chronic diseases. Unfortunately some "healthy products," such as flavored milk, contain high sugar. In the Philippines, such an issue is made worse by local brands not putting nutritional labels on their products. Thus, a cheap, home-based method to measure total sugars should be beneficial. In this paper, we have shown that after incubation with invertase and lactase, a glucometer can be used to measure total sugars in flavored milk on-site. All experiments except the weighing of invertase and lactose were done in a home setting for actual proof of concept. The total sugar …


A Tale Of Two Working Landscapes, Sage C. Sutcliffe Jan 2024

A Tale Of Two Working Landscapes, Sage C. Sutcliffe

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.


Exploring The Consistency Of Flow Regimes Within And Among Ecoregions Of The Southeastern United States, Frank Paul Braun Iv Jan 2024

Exploring The Consistency Of Flow Regimes Within And Among Ecoregions Of The Southeastern United States, Frank Paul Braun Iv

Electronic Theses and Dissertations

Human manipulation of river systems has long been a known contributor to the loss of freshwater biodiversity. By accounting for environmental causes of hydrologic variation among rivers, we can better understand how ecoregion mediates flow regimes and forecast species that may be at risk. Presumably, natural variation associated with ecoregion boundaries exerts strong influence on flow regimes, and may mediate relationships between other features (e.g., land use, dam operations) and hydrology. However, such between-ecoregion variation is poorly investigated, particularly at fine spatial and temporal scales. I characterized 10 hydrologic metrics, representing the five key dimensions of the flow regime (magnitude, …


Herbicide Management Alters Fungal Biomass And Community Composition In Great Lakes Coastal Wetlands, Erica Danae Lathers Jan 2024

Herbicide Management Alters Fungal Biomass And Community Composition In Great Lakes Coastal Wetlands, Erica Danae Lathers

Master's Theses and Doctoral Dissertations

Wetlands provide many ecosystem services, and invasive species and their management can alter these services. Plant responses to wetland management actions are typically monitored, but less is known about how soils respond. Phragmites australis, an invasive wetland plant, can alter soil conditions, potentially impacting soil microbial structure and function. We sampled soil communities in Great Lakes coastal wetlands in southeastern Michigan dominated by Phragmites and sites that had been previously invaded by Phragmites then treated with herbicide from 2011-2017, to understand how herbicide management alters soil fungal communities. We assessed microbial and fungal biomass, fungal community composition, greenhouse gas emissions, …


A Gis Tool For Optimal Forage Species Selection, David B. Hannaway, Christopher Daly, Michael D. Halbleib, Linda Brewer, Sophie Baur, Chelsea Clark, Emilie Krecklow, Scott Bassett Jan 2024

A Gis Tool For Optimal Forage Species Selection, David B. Hannaway, Christopher Daly, Michael D. Halbleib, Linda Brewer, Sophie Baur, Chelsea Clark, Emilie Krecklow, Scott Bassett

IGC Proceedings (1997-2023)

To determine appropriate forage species for US ecoregions, geographic information technologies (GIS) are being used to create climatic and soil factor maps. Excel spreadsheets and RStudio are used to create response functions of forage species to minimum and maximum temperature, annual precipitation, soil pH, soil salinity, and salinity. National forage data and expert opinion will evaluate quantitative tolerances, seasonal yield profiles, and pollinator suitability. These maps and agronomic and livestock use information will be shared with forage specialists and farmers to provide alternatives for improved perenniality, increased diversity, and system circularity. Future work will include development and evaluation of climate …


A Soil-Plant-Atmosphere Continuum Model To Simulate Seedling Response To Water Stress, Michael Kurt Kendree Jr. Jan 2024

A Soil-Plant-Atmosphere Continuum Model To Simulate Seedling Response To Water Stress, Michael Kurt Kendree Jr.

Graduate Student Theses, Dissertations, & Professional Papers

Most current ecohydrologic models simplify the hydraulics that are at play in plant-water relationships by assuming that the water content within the plant is static. In reality, plants have a relative water content that varies with time in response to environmental stresses. To some extent, variations in plant relative water content are regulated by changes in the osmotic potential of water within plant cells, which contributes to the resilience of plants during periods of water shortage. We present a model that simulates plant water transport and storage within the soil-plant-atmosphere continuum. The model incorporates the role of osmotic regulation in …


Better Understanding The Barred Owl, Adam Lee Potts Jan 2024

Better Understanding The Barred Owl, Adam Lee Potts

Graduate Student Theses, Dissertations, & Professional Papers

This thesis research presents an analysis of barred owl nest site selection in an understudied region of their expanded range. The barred owl has dramatically expanded its range westwards over the last 150 years, prompting multiple conflicting reinterpretations of their species account. Hypotheses of range expansion are reviewed to provide context for this study’s research. This study gathers empirical data on nest site selection in the mixed conifer forests of Montana’s Seeley-Swan and Mission Valleys. Eight barred owl nests were located following extensive territory surveys. Field measurements of tree height and diameter using USFS Forest Inventory and Analysis (FIA) plot …


Model-Based Deep Autoencoders For Clustering Single-Cell Rna Sequencing Data With Side Information, Xiang Lin Dec 2023

Model-Based Deep Autoencoders For Clustering Single-Cell Rna Sequencing Data With Side Information, Xiang Lin

Dissertations

Clustering analysis has been conducted extensively in single-cell RNA sequencing (scRNA-seq) studies. scRNA-seq can profile tens of thousands of genes' activities within a single cell. Thousands or tens of thousands of cells can be captured simultaneously in a typical scRNA-seq experiment. Biologists would like to cluster these cells for exploring and elucidating cell types or subtypes. Numerous methods have been designed for clustering scRNA-seq data. Yet, single-cell technologies develop so fast in the past few years that those existing methods do not catch up with these rapid changes and fail to fully fulfil their potential. For instance, besides profiling transcription …


Covalent Inhibition Of Enzyme Sortase A As A New Pathway Against Bacterial Resistance Of Staphylococcus Aureus, Umyeena Bashir Dec 2023

Covalent Inhibition Of Enzyme Sortase A As A New Pathway Against Bacterial Resistance Of Staphylococcus Aureus, Umyeena Bashir

Master's Theses

The continued rise of antibiotic-resistant bacteria, such as MRSA (methicillin-resistant Staphylococcus aureus), has made the discovery of novel antibiotics critical. While bacteriostatic and bactericidal antibiotics inevitably exert evolutionary pressure on bacteria to develop resistance, small molecules that target mechanisms of bacterial virulence present a promising alternative for treatment. Sortase A (Srt A), a cysteine protease of S. aureus, promotes bacterial virulence by covalently attaching proteins such as pilin to the bacterial surface, enabling bacterial adhesion to mammalian cells. Inhibitory studies of this enzyme have gained prominent interest as a new pathway for drug development since blocking this enzyme's ability to …


Conversion Of Cellulose To 5-Hydroxymethylfurfural As Sustainable Energy: A Bibliometric Analysis By Vosviewer, Royyan Faradis, Ardiansyah Bagus Suryanto, Irmina Kris Murwani Dec 2023

Conversion Of Cellulose To 5-Hydroxymethylfurfural As Sustainable Energy: A Bibliometric Analysis By Vosviewer, Royyan Faradis, Ardiansyah Bagus Suryanto, Irmina Kris Murwani

Journal of Environmental Science and Sustainable Development

The developments of the global economy and society impact resources and the environment. This condition requires an alternative to find new, safe, and sustainable energy types. The conversion of cellulose to 5-hydroxymethylfurfural (5-HMF) has become a significant area of research interest. It has triggered the development of research directions related to biomass and energy because it can be an intermediary source for making polymers, solvents, pharmaceuticals, and biofuels. The primary objective of this study is to give a bibliometric analysis of 1753 reports on the development of research on cellulose conversion to 5-HMF from 1965 to 2021. The data were …


Role Of Urban Parks In Carbon Sequestration– A Case Study Of Safari Park, Karachi, Pakistan, Amna Bano, Minzah Shehzad, Hasnain Kazmi, Jamshaid Iqbal Dec 2023

Role Of Urban Parks In Carbon Sequestration– A Case Study Of Safari Park, Karachi, Pakistan, Amna Bano, Minzah Shehzad, Hasnain Kazmi, Jamshaid Iqbal

Journal of Bioresource Management

Urban parks besides their recreational use can be the potential source of climate mitigation through carbon sequestration. Present study aims to identify the carbon sequestration potential of Safari Park which is by far the largest public park of Karachi established in 1970 covering an area of 0.72 km2. A total of 153 individual trees belonging to 25 species and 14 families were included in the study. Five dominant species with highest Important Value Index (IVI) were Cocos nucifera (14.62 %), Azadirachta indica (14.21 %), Guaiacum officinale (9.93 %), Washington robusta (9.31 %) and Delonix regia (7.11 %). The …


The Effect Of Walnut Shell Ash On The Properties Of Cement Paste And Mortar: A Study On Partial Replacement Of Cement, Ali Shebli, Jamal Khatib, Adel Elkordi Dec 2023

The Effect Of Walnut Shell Ash On The Properties Of Cement Paste And Mortar: A Study On Partial Replacement Of Cement, Ali Shebli, Jamal Khatib, Adel Elkordi

BAU Journal - Science and Technology

In the pursuit of a more sustainable future, the utilization of agricultural waste in cementitious products has emerged as a popular and effective solution. The current study explores the feasibility of incorporating ash derived from walnut nutshells, considered agro residues, into eco-friendly blended cement paste and mortars to examine its impact on their properties. A range of blended cement mixtures was formulated by incorporating walnut shell ash (WSA) in three varying proportions of 5%, 10%, and 15% relative to the weight of the cement. Tests were conducted to investigate the properties of the blended cement paste and mortar incorporating WSA, …


Optimization Of The Bio-Synthesis Of Magnesium Nanoparticles From Staphylococcus Haemolyticus: A Pilot Study, Mariam Bassam, Malak Mezher, Mahmoud Khalil Dec 2023

Optimization Of The Bio-Synthesis Of Magnesium Nanoparticles From Staphylococcus Haemolyticus: A Pilot Study, Mariam Bassam, Malak Mezher, Mahmoud Khalil

BAU Journal - Science and Technology

Nanotechnology is developing rapidly. This field has many influences in humans’ life. Nanoparticles (NPs) have many unique properties including the size, shape, morphology, and surface area. The synthesis of NPs could be achieved by three ways: physical, chemical, and biological. However, the biological synthesis of NPs has a priority on the other domains due to its safety and environmental friendship. In this regard, the main objective of this study was to synthesize magnesium (Mg) NPs from the bacterium S. haemolyticus which was isolated from the Lebanese wastewater. Different parameters were applied to detect the best conditions to produce the highest …


Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia Dec 2023

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …


Variables Affecting The Extraction Of Antioxidants In Cold And Hot Brew Coffee: A Review, Brian Yust, Frank Wilkinson, Niny Rao Dec 2023

Variables Affecting The Extraction Of Antioxidants In Cold And Hot Brew Coffee: A Review, Brian Yust, Frank Wilkinson, Niny Rao

College of Life Sciences Faculty Papers

Coffee beans are a readily available, abundant source of antioxidants used worldwide. With the increasing interest in and consumption of coffee beverages globally, research into the production, preparation, and chemical profile of coffee has also increased in recent years. A wide range of variables such as roasting temperature, coffee grind size, brewing temperature, and brewing duration can have a significant impact on the extractable antioxidant content of coffee products. While there is no single standard method for measuring all of the antioxidants found in coffee, multiple methods which introduce the coffee product to a target molecule or reagent can be …


Long Oligodeoxynucleotides: Chemical Synthesis, Isolation Via Catching-By-Polymerization, Verification Via Sequencing, And Gene Expression Demonstration, Yipeng Yin, Reed Arneson, Alexander Apostle, Adikari M.D.N. Eriyagama, Komal Chillar, Emily Burke, Martina Jahfetson, Yinan Yuan, Shiyue Fang Dec 2023

Long Oligodeoxynucleotides: Chemical Synthesis, Isolation Via Catching-By-Polymerization, Verification Via Sequencing, And Gene Expression Demonstration, Yipeng Yin, Reed Arneson, Alexander Apostle, Adikari M.D.N. Eriyagama, Komal Chillar, Emily Burke, Martina Jahfetson, Yinan Yuan, Shiyue Fang

Michigan Tech Publications, Part 2

Long oligodeoxynucleotides (ODNs) are segments of DNAs having over one hundred nucleotides (nt). They are typically assembled using enzymatic methods such as PCR and ligation from shorter 20 to 60 nt ODNs produced by automated de novo chemical synthesis. While these methods have made many projects in areas such as synthetic biology and protein engineering possible, they have various drawbacks. For example, they cannot produce genes and genomes with long repeats and have difficulty to produce sequences containing stable secondary structures. Here, we report a direct de novo chemical synthesis of 400 nt ODNs, and their isolation from the complex …


Developing Characteristic Resource Plants To Build A Beautiful China, Lei Shi, Zheng'an Liu, Lijun Wang, Qingyan Shu, Meiyu Sun, Wei Duan, Hui Li Dec 2023

Developing Characteristic Resource Plants To Build A Beautiful China, Lei Shi, Zheng'an Liu, Lijun Wang, Qingyan Shu, Meiyu Sun, Wei Duan, Hui Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

It is an important way to solve the contradiction among ecology, production and life in natural protected areas and ecologically fragile region by constructing the three-production integration mode of characteristic resource plants. In order to fully tap and make use of the outstanding characteristics of oil tree peony, wine grape and aromatic plants, this study carried out technology integration of variety screening, planting, harvesting, processing, product research and development, and industrialization demonstration in and around natural protected areas and ecologically fragile region. Through the economic benefits generated, the life of the people in the natural protected areas and ecologically fragile …


An Innovative Restoration Mode “Macrophytes–Fishes–Benthons–Birds” Implemented In Aesthetic Plateau Wetlands, Junxing Yang, Xiaoai Wang, Xiaofu Pan, Yuanwe Zhang, Heqi Wu, Anli Wu Dec 2023

An Innovative Restoration Mode “Macrophytes–Fishes–Benthons–Birds” Implemented In Aesthetic Plateau Wetlands, Junxing Yang, Xiaoai Wang, Xiaofu Pan, Yuanwe Zhang, Heqi Wu, Anli Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Affected by both increasing human activities and climate change, Yunnan Plateau lakes were faced with threats such as water level decreasing, water-body reducing, and severe pollution. Many indigenous species were endangered or even disappeared. The ecological restorations implemented since 1980s almost all used alien species. As an inevitable result, severe negative impacts from alien species were observed on the Plateau wetland ecosystem and indigenous species. To solve these problems, with the support of relevant projects, an innovative restoration mode mainly with indigenous flag-species “macrophytes – fishes – benthons – birds” was proposed. This innovative mode was implemented respectively in Dianchi …


Innovation And Practice On Biodiversity Conservation In Sanjiangyuan National Park, Xinquan Zhao, Shixiao Xu, Liang Zhao, Tongzuo Zhang, Linyong Hu, Qi Li, Tongqing Guo Dec 2023

Innovation And Practice On Biodiversity Conservation In Sanjiangyuan National Park, Xinquan Zhao, Shixiao Xu, Liang Zhao, Tongzuo Zhang, Linyong Hu, Qi Li, Tongqing Guo

Bulletin of Chinese Academy of Sciences (Chinese Version)

Sanjiangyuan National Park, is one of the first batch of national parks in China, and serves as the largest national park in China. As an important ecological security barrier and a alpine biological germplasm resource base, it has significant conservation value in China and even in the world. Lots of protocols have been taken aiming at ecological tacking protection issues including loss of biodiversity and wildlife habitats, degradation of alpine grassland and overgrazing in Sanjiangyuan National Park. It promotes the implementation of major ecological restoration projects, and has formed the Sanjiangyuan National Park Biodiversity Conservation and Ecological Protection Program with …


Conception On Asian Elephant Ecological Corridor Planning With Implications For Conservation, Xueyou Li, Qiupeng Yu, Zhechang Hu, Xuelong Jiang Dec 2023

Conception On Asian Elephant Ecological Corridor Planning With Implications For Conservation, Xueyou Li, Qiupeng Yu, Zhechang Hu, Xuelong Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

In order to practice the concept of coordinated development of “Lucid Waters and Lush Mountains are Invaluable Assets” and “mountains, rivers, forests, farmlands, lakes, grasslands and deserts are part of the community of life”, this study takes “pursuing green development and promoting harmony between humanity and nature” proposed in the report of the 20th National Congress of the Communist Party of China as the theoretical guidance. With the goal of enhancing ecosystem integrity and connectivity, enhancing population communication, enhancing population viability, and providing a model for the construction of ecological corridors for flagship species, based on the current distribution and …


Lipid Membrane Self-Assembly And Synthesis In The Lab By Rapid, Low-Cost Microfluidics Approaches, Kathleen Hardwick, Shane O'Reilly Dec 2023

Lipid Membrane Self-Assembly And Synthesis In The Lab By Rapid, Low-Cost Microfluidics Approaches, Kathleen Hardwick, Shane O'Reilly

SURE Journal: Science Undergraduate Research Experience Journal

Lipid membranes, which self-assemble in nature and under laboratory conditions, can form vesicles called liposomes. The main uses for liposomes are in drug delivery systems and as animal cell models. From the initial research into lipid membrane science, to the systematic literature review using Web of Science, to refining the project scope, to the description of the method, this project follows the process of developing a method for lipid membrane self-assembly and synthesis in the lab. The result was a rapid prototyping method for fabricating microfluidic devices to test different designs for channels, for use with a liposome synthesis protocol. …


Regulation Of Mirnas In Obesity And Diabetes, Eva Maher, Ava O'Meara, Cathy Brougham Dec 2023

Regulation Of Mirnas In Obesity And Diabetes, Eva Maher, Ava O'Meara, Cathy Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Introduction: The prevalence of obesity and obesity-related secondary disorders has increased dramatically in recent years. Dysregulated microRNA (miRNA) expression has been linked to the development of obesity and its associated disorders. Adipose derived stem cells (ADSCs) are promising cell models of obesity, obesity-related inflammation and diabetes. Furthermore, miRNA expression profiles have emerged as promising targets for the novel treatment of diseases such as obesity. In order to enhance miRNA-based therapies, the miRNA expression profile of obesity and its related disorders must be monitored to further understand the underlying mechanisms of obesity and to identify novel targets.

Aim: The aim of …


The Potential Of Stem Cell Therapy In Multiple Sclerosis Treatment: A Review, Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham Dec 2023

The Potential Of Stem Cell Therapy In Multiple Sclerosis Treatment: A Review, Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Multiple Sclerosis is an autoimmune and neurodegenerative disease of the central nervous system. There are currently 2.8 million people living with Multiple Sclerosis worldwide, including 9000 people in Ireland, with a prevalence of 193 per 100,000 people. Symptoms of Multiple Sclerosis include sensory loss, fatigue, cognitive dysfunction, spasticity, depression, optic neuritis, gait ataxia, diplopia, and loss of bladder control. Currently, there is no standardised treatment or cure for Multiple Sclerosis with many strategies focusing on symptoms. Stem cells have emerged as promising approaches for Multiple Sclerosis therapeutics. Clinical trials primarily focus on mesenchymal stem cell-based therapies for Multiple Sclerosis. Furthermore, …