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Full-Text Articles in Veterinary Microbiology and Immunobiology
Pharmacokinetics Of Tulathromycin In Pregnant Ewes (Ovis Aries) Challenged With Campylobacter Jejuni, Michael Yaeger, Jonathan P. Mochel, Zuowei Wu, Paul Plummer, Orhan Sahin, Joseph Smith, Melda Ocal, Ashenafi Beyi, Changyun Xu, Qijing Zhang, Ronald W. Griffith
Pharmacokinetics Of Tulathromycin In Pregnant Ewes (Ovis Aries) Challenged With Campylobacter Jejuni, Michael Yaeger, Jonathan P. Mochel, Zuowei Wu, Paul Plummer, Orhan Sahin, Joseph Smith, Melda Ocal, Ashenafi Beyi, Changyun Xu, Qijing Zhang, Ronald W. Griffith
Faculty Publications and Other Works -- Large Animal Clinical Sciences
The purpose of this study was to evaluate the pharmacokinetics of tulathromycin in the plasma and maternal and fetal tissues of pregnant ewes when administered within 24 hours of a single, IV Campylobacter jejuni (C. jejuni) challenge. Twelve, pregnant ewes between 72–92 days of gestation were challenged IV with C. jejuni IA3902 and then treated with 1.1 ml/45.36 kg of tulathromycin subcutaneously 18 hours post-challenge. Ewes were bled at predetermined time points and euthanized either at a predetermined time point or following the observation of vaginal bleeding or abortion. Following euthanasia, tissues were collected for bacterial …
Clinical Presentations And Antimicrobial Susceptibilities Of Corynebacterium Cystitidis Associated With Renal Disease In Four Beef Cattle, Joseph Smith, Adam C. Krull, Jennifer A. Schleining, Rachel J. Derscheid, Amanda J. Kreuder
Clinical Presentations And Antimicrobial Susceptibilities Of Corynebacterium Cystitidis Associated With Renal Disease In Four Beef Cattle, Joseph Smith, Adam C. Krull, Jennifer A. Schleining, Rachel J. Derscheid, Amanda J. Kreuder
Faculty Publications and Other Works -- Large Animal Clinical Sciences
Background
Renal disease caused by Corynebacterium cystitidis in beef cattle may be misclassified as Corynebacterium renale, and limited information about C. cystitidis infections in beef cattle currently is available.
Objective
To describe clinical presentation, diagnosis, minimum inhibitory concentrations (MICs), and outcome of renal disease caused by C. cystitidis in beef cattle.
Methods
Retrospective case series.
Animals
Four client-owned beef cattle.
Results
All affected cattle had anorexia as a primary complaint. Of the 3 that had ante-mortem diagnostic tests performed, all had pyelonephritis based on azotemia in combination with urinalysis and ultrasonographic findings. Cultures yielded C. cystitidis which was identified …