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Veterinary Infectious Diseases Commons™
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Full-Text Articles in Veterinary Infectious Diseases
The Human/Animal Interface: Emergence And Resurgence Of Zoonotic Infectious Diseases, Michael Greger
The Human/Animal Interface: Emergence And Resurgence Of Zoonotic Infectious Diseases, Michael Greger
Michael Greger, MD, FACLM
Emerging infectious diseases, most of which are considered zoonotic in origin, continue to exact a significant toll on society. The origins of major human infectious diseases are reviewed and the factors underlying disease emergence explored. Anthropogenic changes, largely in land use and agriculture, are implicated in the apparent increased frequency of emergence and reemergence of zoonoses in recent decades. Special emphasis is placed on the pathogen with likely the greatest zoonotic potential, influenzavirus A.
House Finch Populations Differ In Early Inflammatory Signaling And Pathogen Tolerance At The Peak Of Mycoplasma Gallisepticum Infection, James S. Adelman, Laila Kirkpatrick, Jessica L. Grodio, Dana M. Hawley
House Finch Populations Differ In Early Inflammatory Signaling And Pathogen Tolerance At The Peak Of Mycoplasma Gallisepticum Infection, James S. Adelman, Laila Kirkpatrick, Jessica L. Grodio, Dana M. Hawley
James S. Adelman
Host individuals and populations often vary in their responses to infection, with direct consequences for pathogen spread and evolution. While considerable work has focused on the mechanisms underlying differences in resistance—the ability to kill pathogens— we know little about the mechanisms underlying tolerance— the ability to minimize fitness losses per unit pathogen. Here, we examine patterns and mechanisms of tolerance between two populations of house finches (Haemorhous [formerly Carpodacus] mexicanus) with different histories with the bacterial pathogen Mycoplasma gallisepticum (MG). After infection in a common environment, we assessed two metrics of pathology, mass loss and eye lesion severity, as proxies …