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Veterinary Infectious Diseases Commons™
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Full-Text Articles in Veterinary Infectious Diseases
The Effects Of Bovine Viral Diarrhea Virus And Bovine Herpesvirus Type 1 On Monocyte-Derived Dendritic Cells, Jacob Sobraske
The Effects Of Bovine Viral Diarrhea Virus And Bovine Herpesvirus Type 1 On Monocyte-Derived Dendritic Cells, Jacob Sobraske
Electronic Theses and Dissertations
Bovine viral diarrhea virus (BVDV) and bovine herpesvirus type 1 (BHV-1) are important pathogens that affect cattle. In this in vitro study, the main goal was determining the direct effects of BVDV and BHV-1 infections of monocyte-derived dendritic cells (MDDC) on cytokine mRNA expression. For the BVDV infected MDDC experiments, Holstein Friesian and Brown Swiss calves were included with a breed comparison with cytokine expression. Surface marker expression was also measured in BHV-1-infected MDDCs. For both viruses, a high virulent strain (1373 for BVDV and Cooper for BHV-1) and lower virulent strains (20508 for BVDV and Los Angeles for BHV-1) …
Understanding The Effect Of Bvdv On Innate Immune Response Of Neutrophils, Neelu Singh Thakur
Understanding The Effect Of Bvdv On Innate Immune Response Of Neutrophils, Neelu Singh Thakur
Electronic Theses and Dissertations
Bovine viral diarrhea virus (BVDV) is one of the highly prevalent and economically important diseases of cattle industry worldwide. The two major consequences of this disease are persistent infection and immunosuppression. Several studies have been done to determine the underline mechanisms of BVDV-induced immunosuppression targeting antigen presenting cells, adaptive immune system cells and cytokine gene expression. However, very little research has been done to determine the effect of BVDV on neutrophils. Neutrophils are one of the most abundant while blood cells (WBC) in the peripheral blood, which play a critical role in the innate as well as adaptive immune response. …