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Tracing The Origin Of The Recent Rise In Neuropathogenic Ehv-1, Kathryn Laura Smith
Tracing The Origin Of The Recent Rise In Neuropathogenic Ehv-1, Kathryn Laura Smith
University of Kentucky Master's Theses
Equine herpesvirus type-1(EHV-1) is a complex virus known for inducing various forms of disease in horses. In recent years, the number of cases of neurological disease caused by this virus has increased. While there are a number of possible sources for this recent surge, this project set out to determine if a genotypic shift in the latent population of the virus in favor of the neuropathogenic form of EHV-1 is the basis for the recent increase in frequency of EHV-1 neurologic disease. To ascertain if such a shift has in fact occurred, 450 EHV-1 isolates were obtained from fetal tissues …