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Full-Text Articles in Large or Food Animal and Equine Medicine

Local Anesthetics As Pain Therapy In Horses, Reza Seddighi Dvm, Ms, Phd, Dip Acva Nov 2010

Local Anesthetics As Pain Therapy In Horses, Reza Seddighi Dvm, Ms, Phd, Dip Acva

Faculty Publications and Other Works -- Large Animal Clinical Sciences

Local Anesthetics as Pain Therapy in Horses Thomas J. Doherty MVB, MSc, and M. Reza Seddighi DVM, PhD

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, The University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA

This article describes the rationale behind the use of systemically administered lidocaine as an analgesic. The analgesic efficacy of intravenously administered lidocaine is well documented by studies in human patients and laboratory animals. The mechanism by which systemically administered lidocaine produces analgesia is uncertain but is thought to include action at sodium, calcium, and potassium channels and the N-methyl-D-aspartate acid receptor. …


Local Anesthetics As Pain Therapy In Horses, Reza Seddighi Dvm, Ms, Phd, Dip Acva Nov 2010

Local Anesthetics As Pain Therapy In Horses, Reza Seddighi Dvm, Ms, Phd, Dip Acva

Reza Seddighi

Local Anesthetics as Pain Therapy in Horses Thomas J. Doherty MVB, MSc, and M. Reza Seddighi DVM, PhD

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, The University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA

This article describes the rationale behind the use of systemically administered lidocaine as an analgesic. The analgesic efficacy of intravenously administered lidocaine is well documented by studies in human patients and laboratory animals. The mechanism by which systemically administered lidocaine produces analgesia is uncertain but is thought to include action at sodium, calcium, and potassium channels and the N-methyl-D-aspartate acid receptor. …